Clinical trials: sponsored by Montefiore Medical Center
Corona Virus Infection
Feasibility of a Self-guided Exercise Program Among Hospitalized COVID-19 Patients
The investigators' aim is to conduct a study looking into safety and feasibility study of Covid patients participating in a self-guided exercises program while admitted to the hospital.
- Trial name
- NCT04821531
- Testing
- PT Pal, Exercise Manual
- Where
- United States
- Sponsor
- Montefiore Medical Center
Stress, Anesthesia
LEGO MRI: Decreasing the Need for Sedation, and Improving Patient Anxiety.
The objective of the LEGO®Bricks MRI project is to study a new play-based tool for use in children preparing to undergo MRI and evaluate its ability to reduce the need for anesthesia.
- Conditions
- Stress, Anesthesia, Children, Only, Anxiety
- Trial name
- LEGO MRI (NCT04172909)
- Testing
- LEGO Bricks MRI, Mock MRI tube
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
COVID-19, Cardiopulmonary Disease
Comparing Inpatient COVID-19 Outcomes in 2 Different PT Dosing Groups
The objective of this study is to compare the effects of twice-a-day 15-minute sessions of inpatient physical therapy (PT) to the standard daily 30 minute sessions.
- Conditions
- COVID-19, Cardiopulmonary Disease, Weakness, Muscle, Hypoxia
- Trial name
- CCPT (NCT04844307)
- Testing
- Shorter duration higher frequency PT, Standard PT
- Sponsor
- Montefiore Medical Center
Acute Pain
Montefiore Opioid and Pain Study
This study will determine pain and opioid outcomes 3 \& 6 months after an emergency department visit for acute pain. This is an observational study.
- Trial name
- MOPS (NCT03375645)
- Testing
- Any oral opioid
- Where
- United States
- Volunteers
- 462 people
- Sponsor
- Montefiore Medical Center
COVID
Use of Remote Monitoring for COVID-19 Patient
The central hypothesis motivating this study is that remote patient monitoring (RPM) of infectious disease patients can efficiently facilitate self-isolation.
- Trial name
- RPM (NCT04425720)
- Testing
- LifeSignals Biosensor 1AX*, Standard of Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Montefiore Medical Center
Anesthesia, Local
Effective Use of Pecs and Transversus Thoracics Plane Blocks for Subcutaneous Cardiac Pacemaker Insertion: A Case Series
Participants that undergo permanent cardiac pacemaker implantation can often present with challenging anesthetic management plans for the anesthesia provider.
- Trial name
- NCT03899701
- Testing
- PEC I and PEC II blocks
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Parenting, Family Relationships
Montefiore Medical Center Healthy Marriage and Relationship Education Program
The proposed program will flexibly provide an array of relationship promotion activities incorporating case management and job placement/career advancement activities: marriage and relationship education; pre-marital education…
- Trial name
- NCT03697421
- Testing
- Relationship Education, Employment Services
- Where
- United States
- Volunteers
- 1,029 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Drug Hypersensitivity, Penicillin Allergy
Drug Challenges Without Prior Skin Testing
The investigators are conducting a prospective study to determine the safety and outcomes of placebo-controlled graded drug challenges without prior skin testing in patients with a low-risk history of antibiotic hypersensitivity…
- Conditions
- Drug Hypersensitivity, Penicillin Allergy, Antibiotic Allergy
- Trial name
- NCT03158831
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Post-Traumatic Headache
Metoclopramide for Post Traumatic Headache
Nearly 1.5 million patients present to US emergency departments annually following head trauma. Headache is a frequent symptom of victims of head trauma.
- Trial name
- NCT03220958
- Testing
- Metoclopramide, Diphenhydramine, Normal saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
Hidradenitis Suppurativa, Hidradenitis
Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa
To establish the safety of radiotherapy in the treatment of advanced hidradenitis suppurativa. Patients will receive radiotherapy treatment over one week and then they will be followed for the next three months.
- Trial name
- RTHS (NCT03040804)
- Testing
- Low dose Radiotherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Montefiore Medical Center
Prader-Willi Syndrome, Hyperphagia
Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
The investigators propose a randomized double-blind 8 week treatment trial of intranasal oxytocin (IN-OXT) vs. placebo in 24 subjects aged 5 to 18 years with PWS in order to assess IN-OXT's affect on (1) Eating behaviors (2)…
- Trial name
- OXT-PWS (NCT02629991)
- Testing
- Intranasal Oxytocin (IN-OXT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Myelodysplastic Syndromes
Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS)
This is a phase I study designed to assess the maximum tolerated dose (MTD) of pyrimethamine and provide the recommended Phase 2 dose (RP2D) for the treatment of intermediate/high-risk MDS that is refractory to or relapsed after…
- Trial name
- NCT03057990
- Testing
- Pyrimethamine
- Where
- United States
- Sponsor
- Montefiore Medical Center
Migraine
Greater Occipital Nerve Block Versus Metoclopramide
We are comparing a type of nerve block called greater occipital nerve block versus standard therapy among patients who present to an emergency department for acute migraine. This is a randomized, double-blind, double dummy study.
- Trial name
- NCT03269435
- Testing
- Greater occipital nerve block with bupivacaine, Metoclopramide
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Montefiore Medical Center
Surgery
Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Currently there is a nationwide epidemic in opioid abuse and overdose deaths. While the opioid epidemic is multi-factorial one major source of excess opioids may be over-prescribing in the post-operative period.
- Trial name
- NCT03588910
- Testing
- Acetaminophen, Ibuprofen 600 mg, Oxycodone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Androgenetic Alopecia
Thulium Laser and KeraFactor for the Treatment of Androgenetic Alopecia
The objective of this clinical study is to assess the safety and efficacy of using a laser and hair growth factors in the treatment of male-pattern hair loss.
- Trial name
- NCT04882969
- Testing
- Fractionated Thulium laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pregnancy, Premature Rupture of Membranes
Cervical Ripening in Premature Rupture of Membranes
Premature rupture of membranes (PROM) is diagnosed by demonstrating amniotic fluid in the vaginal canal before the onset of labor.
- Conditions
- Pregnancy, Premature Rupture of Membranes, Preterm Premature Rupture of Membranes, Unfavorable Cervix
- Trial name
- NCT02314728
- Testing
- Misoprostol, Oxytocin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Medical Training
Virtual Reality on Efficacy of Donning and Doffing PPE
All front-line healthcare workers in the United States must receive PPE training but there is no gold standard for doing so(1). Training methods vary, with the conventional approaches being in-person or video presentations (2).
- Trial name
- NCT04937257
- Testing
- Virtual Reality, E-module
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Nerve Pain
The Feasibility of Performing Erector Spinae (ESP) Nerve Block in Bariatric Patients; a Case Series Study
This study is a pilot study to assess the effectiveness of erector spinae (ESP) nerve blocks for postoperative pain control following bariatric surgery.
- Trial name
- NCT04477525
- Testing
- Ultrasound Guided Erector Spinae Plane (ESP) Nerve Block, Bupivacaine Injection
- Sponsor
- Montefiore Medical Center
Congenital Hyperinsulinism, Insulinoma
Pasireotide in Hyperinsulinemic Hypoglycemia
This is a small controlled pilot study to assess the effect of subcutaneous pasireotide on preventing hypoglycemia due to hyperinsulinism, including congenital hyperinsulinism and insulinoma.
- Conditions
- Congenital Hyperinsulinism, Insulinoma, Hyperinsulinism
- Trial name
- NCT03053284
- Testing
- Pasireotide 0.6Mg Solution for Injection, Saline Solution
- Sponsor
- Montefiore Medical Center
Hypophosphatemia, Renal Transplant
Using Cinacalcet to Treat the Hypophosphatemia of Early Kidney Transplant
The purpose of the study is to determine whether cinacalcet, used in patients with secondary hyperparathyroidism to control excessive parathyroid hormone, can normalize low blood phosphorus that is commonly seen in patients who…
- Trial name
- NCT01011114
- Testing
- Cinacalcet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Montefiore Medical Center