Clinical trials: sponsored by Montefiore Medical Center
Adherence, Patient, HIV/AIDS
Group Clinical Visit Adherence Intervention for HIV+ Women of Color
The investigators will conduct a pilot randomized controlled trial (RCT) of Sisters-GPS with HIV-positive women of color with suboptimal ARV adherence and detectable HIV viral loads (VL).
- Conditions
- Adherence, Patient, HIV/AIDS, Group Meetings
- Trial name
- NCT03109743
- Testing
- Sisters-GPS: Group Clinical Visits, Control: One-on-one Adherence Counseling
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acute Migraine
Valproate Versus Ketorolac Versus Metoclopramide
This randomized study is testing 3 different intravenous medications to see which one is best for acute migraine. The three medications are metoclopramide, valproate, and ketorolac.
- Trial name
- NCT01267864
- Testing
- Metoclopramide, Ketorolac, Valproate
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Montefiore Medical Center
Childhood Obesity
Feeding Young Children Study: Bottle Weaning Intervention
This Integrated Project (Research + Extension) aims to reduce the risk of early childhood overweight through changing bottle-feeding behavior.
- Trial name
- FYCS (NCT00756626)
- Testing
- Bottle Weaning Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Montefiore Medical Center
Complications; Cesarean Section, Surgical Wound Infection
Subcuticular Suture for Cesarean Skin Incision Closure
A comparison of the type of suture used for cesarean skin incision approximation and the subsequent rate of wound complications has not been widely studied.
- Trial name
- NCT02459093
- Testing
- poliglecaprone 25 suture, polyglactin 910 suture
- Where
- 2 sites in United States
- Volunteers
- 550 people
- Sponsor
- Montefiore Medical Center
Migraine, Tension-type Headache
Comparing Naproxen to Sumatriptan for Emergency Headache Patients
2/3 of patients discharged from an emergency department after treatment for an acute headache will still be bothered by headache within 24 hours of emergency department (ED) treatment.
- Conditions
- Migraine, Tension-type Headache, Primary Headache Disorder
- Trial name
- HEDNet2 (NCT00449787)
- Testing
- Sumatriptan 100 mg, Naproxen
- Where
- 2 sites in United States
- Volunteers
- 401 people
- Sponsor
- Montefiore Medical Center
Migraine
Metoclopramide for Migraine: A Dose Finding Study
Metoclopramide is an effective intravenous treatment for acute migraine attacks, but we do not know the best dose to administer. This study compares three different doses of metoclorpamide.
- Trial name
- MDFS (NCT00682734)
- Testing
- metoclopramide, Diphenhydramine 25mg
- Where
- United States
- Volunteers
- 349 people
- Sponsor
- Montefiore Medical Center
Autism
Divalproex Sodium ER in Adult Autism
12-week open label treatment trial of divalproex sodium extended release (Depakote ER) in 10 patients with a diagnosis of autism.
- Trial name
- NCT00211796
- Testing
- Divalproex Sodium ER
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Montefiore Medical Center
Obsessive-compulsive Disorder
Topiramate Augmentation in the Treatment of Obsessive-Compulsive Disorder
A 12-week program to examine the effectiveness of topiramate in adjunctive treatment for adults with obsessive-compulsive disorder and who are currently on serotonin reuptake inhibitor medications (ages 18-65).
- Trial name
- NCT00211744
- Testing
- topiramate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Montefiore Medical Center
Pain
Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain
The hydromorphone protocol is more effective than usual care in Emergency Department (ED) patients age 65 years and older in terms of proportion who choose to forgo additional pain medication within 60 minutes post-baseline in…
- Trial name
- NCT01429285
- Testing
- Hydromorphone, Usual care
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acute Pain
Clinical Trial Comparing Two Protocols Using Intravenous (IV) Hydromorphone
The purpose of this study is to compare two opioid protocols ("H2O" and "1+1") for the treatment of acute severe pain in the emergency department.
- Trial name
- NCT01311895
- Testing
- H2O, 1+1
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Montefiore Medical Center
Pain
Comparing Intravenous Hydromorphone to Usual Care
In this randomized controlled trial, 2 mg intravenous (IV) hydromorphone will be more efficacious than usual care (usual care is analgesic management according to the judgment of the attending physician caring for that patient)…
- Trial name
- NCT01429298
- Testing
- Hydromorphone, Usual care
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Headache
Prospective ED Headache Cohort Study
The purpose of this study is to determine how often headaches recur and to learn how to predict continued suffering from headache after emergency department discharge.
- Trial name
- NCT00313703
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- Montefiore Medical Center
Headache
Metoclopramide Versus Ketorolac for Tension-type Headache
Occasionally, episodic tension-type headache may be severe enough to require an emergency department (ED) visit. The purpose of this study is to compare two commonly used medications to see which is better for tension type…
- Trial name
- NCT01011673
- Testing
- Metoclopramide, Ketorolac
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Montefiore Medical Center
Analgesia After ED Discharge for Extremity Injuries
Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
There will be 3 randomized, double-blinded clinical trials to help determine which of commonly prescribed oral opioid combination is most effective in managing acute extremity pain after discharge from the adult emergency…
- Trial name
- NCT01402375
- Testing
- Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Montefiore Medical Center
HIV Infections
A Comparison of Adherence Rates to Ritonavir and Its Accompanying Protease Inhibitor
Pharmacologic boosting of protease inhibitors with ritonavir has become standard practice in antiretroviral therapy. Patients are instructed to take ritonavir at the same time as its accompanying protease inhibitor.
- Trial name
- NCT00432783
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Montefiore Medical Center
Body Dysmorphic Disorder
Fluoxetine in Pediatric Body Dysmorphic Disorder
This trial will study the effectiveness of the medication fluoxetine for children and adolescents ages 16 and younger with BDD who qualify.
- Trial name
- FDA BDD (NCT00245635)
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Montefiore Medical Center
HIV Infection
A Trial to Determine the Long-term Durability of Virologic Suppression in Kaletra Recipients With Imperfect Adherence
This study will enroll completers of a prior 24 week MEMS cap study of Kaletra adherence, conducted in 2005 - 2006, and repeat the MEMS monitoring for an additional 24 weeks in 2008/2009 on the current antiretroviral anchor drug.
- Trial name
- NCT00785616
- Testing
- MEMS cap monitoring
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Montefiore Medical Center
Smoking, HIV Infections
A Trial to Test the Efficacy of a Tailored Intensive Smoking Cessation Intervention in Persons With HIV (PWHs)
The purpose of this study is to determine whether an intensive, eight session behavioral intervention is superior to standard care in achieving abstinence from cigarettes in smokers living with HIV/AIDS.
- Conditions
- Smoking, HIV Infections, AIDS
- Trial name
- NCT01106638
- Testing
- Positively Smoke Free, Standard care
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Montefiore Medical Center
IBD
Anal Dysplasia in Patients With Inflammatory Bowel Disease
The rationale for this study is that the risk of anal dysplasia in patients with inflammatory bowel disease (IBD) as compared to the general population has yet to be investigated prospectively.
- Trial name
- HPVIBD (NCT01653054)
- Testing
- Anal Pap Smear, HPV DNA Testing
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Montefiore Medical Center
Intubated ICU Patients
Shortened Preoperative Fasts in ICU
Randomized controlled trial assessing the safety and benefits of shortening preoperative fasts on intubated ICU patients undergoing tracheotomy.
- Trial name
- NCT03031379
- Testing
- shortened fast
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Montefiore Medical Center