Clinical trials: sponsored by Montefiore Medical Center
Vasculopathy
Statin InTensity to Prevent Coronary Artery Vasculopathy After Heart Transplantation
The investigator's propose to conduct an open-label randomized controlled trial to determine if higher intensity statin (HS) can reduce CAV in comparison to lower intensity statin (LS) after HT.
- Trial name
- SToP-CAV (NCT05251129)
- Testing
- Atorvastatin 80 Mg Oral Tablet, Pravastatin 40 Mg Oral Tablet
- Sponsor
- Montefiore Medical Center
Aneurysm Cerebral (Unruptured)
Dual Antiplatelet Therapy Adherence With Reminder App Usage
The purpose of this study is to evaluate Dual Antiplatelet Therapy adherence in patients undergoing stent-based endovascular treatment for unruptured cervical and intradural, intracranial aneurysms.
- Trial name
- NCT05071027
- Testing
- Endovascular Neurosurgery
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Montefiore Medical Center
Cardiac Arrest
Discover In-Hospital Cardiac Arrest
The Discover In-Hospital Cardiac Arrest (IHCA) study is a multicenter, prospective observational study aimed at better understanding variations in practice for the post-in-hospital cardiac arrest patient.
- Trial name
- Discover IHCA (NCT06207201)
- Where
- United States
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Autism
Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism
The study is designed to assess the efficacy of treatment with divalproex sodium (DS) vs. placebo in childhood/adolescent autism fulfilling DSM-IV and Autism Diagnostic Interview (ADI) criteria.
- Trial name
- NCT00211757
- Testing
- Divalproex sodium
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Montefiore Medical Center
Sphenopalatine Ganglion Nerve Block
Sphenopalatine Ganglion Block Study
The goal of this clinical trial is to compare the administration and dosage of bupivacaine for sphenopalatine ganglion (SPG) nerve block.
- Trial name
- NCT05707754
- Testing
- Bupivacaine, angiocatheter
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Hiv
Testing Two Models of PrEP Delivery in OBGYN Clinics
The HIV Center for Clinical and Behavioral Studies, the Albert Einstein College of Medicine and the Alliance for Positive Change will test two healthcare models that integrate PrEP into OBGYN services.
- Trial name
- NCT05015855
- Testing
- NP-PC PrEP, OBGYN-PrEP
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acute Kidney Injury, Chronic Kidney Disease
Outcomes of Neonatal Acute Kidney Injury In Premature Infants
The objective of this protocol is to investigate the impact of prematurity, with or without associated acute kidney injury (AKI), on the future risk of chronic kidney disease (CKD) by establishing a patient registry and…
- Trial name
- NCT02375854
- Testing
- Observation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Crohn Disease, Ulcerative Colitis
Digital Behavioral Interventions in Inflammatory Bowel Disease
Given the bidirectionality between psychological distress and disease activity in inflammatory bowel disease (IBD), whereby increased psychological distress exacerbates disease activity and vice versa, psychosocial aspects of IBD…
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases, Stress, Psychological
- Trial name
- NCT04861597
- Testing
- Internet based cognitive behavioral therapy, Digital mood tracking
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Montefiore Medical Center
Prone Positioning, Bronchopulmonary Dysplasia
Prone Versus Supine Positioning and the Impact on Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.
In this pilot study, the investigator team aims to evaluate whether standardized prone positioning compared to usual positioning improves moderate to severe bronchopulmonary dysplasia (BPD) rates as assessed at 36 weeks post…
- Trial name
- NCT04890158
- Testing
- Prone positioning for a total of 6 hours daily
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Montefiore Medical Center
Opioid Use, Opioid Use Disorder
Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance and Commitment Therapy for Opioid Treatment Programs
The overarching goal of this study was to provide patient-centered treatment for chronic pain in opioid treatment programs (OTPs).
- Conditions
- Opioid Use, Opioid Use Disorder, Chronic Pain
- Trial name
- OTP-ACT (NCT06581276)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Montefiore Medical Center
Laryngeal Mask Airways, Airway Management
Study Comparing Intubation Via Video Laryngeal Mask Airways (VLMAs) Versus Video Laryngoscopy
The goal of this clinical trial is to compare the overall performance and patient outcomes of two video-assisted laryngeal mask airways (VLMAs) devices called Safe and Comfortable (SaCo) VLM and SafeLM® (Safe VLM) versus video…
- Conditions
- Laryngeal Mask Airways, Airway Management, Supraglottic Airways, Video-assisted
- Trial name
- NCT06396234
- Testing
- Safe VLM and airway management, Endotracheal intubation using video laryngoscope, SaCo VLM and airway management
- Where
- United States
- Sponsor
- Montefiore Medical Center
Cancer
Booster Dose Trial
The goal of this study is to assess the safety and effectiveness of COVID vaccine booster doses in patients with cancer who have not developed an antibody after the U.S.
- Trial name
- NCT05016622
- Testing
- BNT162b2 vaccine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Montefiore Medical Center
Thrombosis, Hemolysis
Sildenafil To Prevent Clot
The advent of continuous flow (CF) pumps for patients with severe heart failure has led to marked improvements in survival; however, pump operation remains fraught with adverse thrombotic events.
- Trial name
- SToPClot (NCT03199612)
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Montefiore Medical Center
Asthma
Use of a Probiotic Supplement to Prevent Asthma in Infants
The goal of the study is to understand the mechanisms of how antigen presentation affects the developing immune system and subsequently affects susceptibility to, or protects against, asthma development.
- Trial name
- NCT00113659
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Nocturnal Enuresis, Anemia, Sickle Cell
Desmopressin for Bedwetting in Children With SCD
This study assesses if using the medication desmopressin will decrease nightime bedwetting in children with sickle cell disease.
- Trial name
- NCT04420585
- Testing
- Desmopressin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Montefiore Medical Center
Low Back Pain
The Effect of AposTherapy on Pain and Function in a Non Specific Low Back Pain
AposTherapy is a home based exercise program utilizing footwear that causes exercise with normal activity that may significantly improve function in patients with back pain since patients with back pain have altered mechanics of…
- Trial name
- AposBack (NCT03167671)
- Testing
- AposTherapy, Traditional Physical Therapy
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Montefiore Medical Center
Anxiety, Intraoperative Hypertension
The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery
This study investigates whether television viewing or music listening can reduce pre-operative anxiety and improve surgical outcomes for patients undergoing cataract surgery.
- Conditions
- Anxiety, Intraoperative Hypertension, Cataract
- Trial name
- NCT06356324
- Testing
- Music Intervention, Television Intervention
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Migraine
Dexamethasone for Migraine - Dose Comparison
Dexamethasone is an evidence-based treatment of acute migraine. This is a randomized comparison of two different doses of dexamethasone for acute migraine. All patients will also be treated with metoclopramide.
- Trial name
- NCT04112823
- Testing
- Dexamethasone 4mg, Dexamethasone 16mg
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Montefiore Medical Center
Overweight and Obesity
The B'N Fit POWER Initiative: A School-Based Wellness Initiative for Bronx Youth
The findings of this study will establish the feasibility and efficacy of B'N Fit POWER and given the wide presence of MSHP, MMCC and other afterschool programs, there is significant potential for dissemination of B'N Fit POWER…
- Trial name
- BNFit (NCT03565744)
- Testing
- B'N Fit POWER
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Contraction
Noninvasive Monitoring of Uterine Electrical Activity and Fetal Heart Rate: A New External Monitoring Device
The EUM (electrical uterine myography) (OB Tools, Israel) was tested and found to be reliable as a non-invasive method for evaluating uterine contractions and the fetal heart rate.
- Trial name
- EUM (NCT02993354)
- Testing
- The EUM300 (electrical uterine myography)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center