Clinical trials: sponsored by Montefiore Medical Center
Analgesia After ED Discharge for Extremity Injuries
Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
There will be 3 randomized, double-blinded clinical trials to help determine which of commonly prescribed oral opioid combination is most effective in managing acute extremity pain after discharge from the adult emergency…
- Trial name
- NCT01402375
- Testing
- Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Montefiore Medical Center
Body Dysmorphic Disorder
Fluoxetine in Pediatric Body Dysmorphic Disorder
This trial will study the effectiveness of the medication fluoxetine for children and adolescents ages 16 and younger with BDD who qualify.
- Trial name
- FDA BDD (NCT00245635)
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Montefiore Medical Center
Acute Pain
Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain
Patients treated with protocolized pain management (1 mg of IV hydromorphone followed by an additional 1 mg IV hydromorphone if the patient wants more) will have better pain relief and no more adverse events than patients…
- Trial name
- NCT00627367
- Testing
- Hydromorphone, Nonprotocolized
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Cough Reflex Sensitivity
Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo
The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa flavoring, and, dextromethorphan syrup…
- Trial name
- NCT02062710
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Montefiore Medical Center
Pain
Comparative Efficacy of 4 Oral Analgesics
The purpose of this study is to perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED.
- Trial name
- NCT02455518
- Testing
- Oxycodone/acetaminophen, Hydrocodone/acetaminophen, Codeine/acetaminophen
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Montefiore Medical Center
Surgical Site Infection Following Cesarean Delivery
Comparison of Surgical Skin Preps During Cesarean Deliveries
In women that undergo non-emergency cesarean delivery, we are comparing the skin preparation solutions for best outcome of surgical site infection.
- Trial name
- NCT01870583
- Testing
- Iodine povidone, Chlorhexidine, Combination iodine and chlorhexidine
- Where
- 2 sites in United States
- Volunteers
- 1,404 people
- Sponsor
- Montefiore Medical Center
Molluscum Contagiosum
Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum
The purpose of this study is to determine if cantharidin is a safe and effective treatment for molluscum contagiosum in kids
- Trial name
- NCT02665260
- Testing
- Cantharidin, Gauze occlusion bandage
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Bronchiolitis
A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis
The purpose of this study is to determine if nebulized hypertonic saline (or extra salty water mist) helps infants less than 12 months old hospitalized with bronchiolitis (or bad chest colds) get better enough to be discharged…
- Trial name
- NCT01488448
- Testing
- 3% sodium chloride, 0.9% sodium chloride
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Anemia, Sickle Cell, Pain
Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis
The purpose of this study is to determine if intranasal fentanyl can decrease the pain of patients with sickle cell disease who present to the pediatric emergency department with a vaso-occlusive crisis.
- Trial name
- NCT01482091
- Testing
- Fentanyl Citrate, Normal Saline
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Montefiore Medical Center
Juvenile Idiopathic Arthritis
Safety and Effectiveness of Rilonacept for Treating Systemic Juvenile Idiopathic Arthritis in Children and Young Adults
Systemic juvenile idiopathic arthritis (SJIA) is a type of arthritis that typically occurs before 16 years of age. SJIA usually involves heat, pain, swelling, and stiffness in the body's joints.
- Trial name
- NCT00534495
- Testing
- Rilonacept
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Montefiore Medical Center
Nausea, Extrapyramidal Symptoms
The Montefiore Metoclopramide Study
Metoclopramide is a dopamine antagonist frequently used for the treatment of nausea, vomiting, and migraine headaches in Emergency Departments.
- Trial name
- NCT00475306
- Testing
- metoclopramide 10 mg, Diphenhydramine 25 mg, Metoclopramide 20 mg
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Montefiore Medical Center