Clinical trials: sponsored by Montefiore Medical Center
Low Back Pain
Ibuprofen With or Without Acetaminophen for Low Back Pain
This is a randomized clinical trial comparing two interventions for acute low back pain: 1. Ibuprofen + acetaminophen 2. Ibuprofen + placebo Participants will include patients who present to an emergency room for management of…
- Trial name
- NCT03554018
- Testing
- Acetaminophen, Ibuprofen 600 mg, Educational intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Montefiore Medical Center
Musculoskeletal Pain
Acetaminophen (APAP) +/- Oxycodone
This is an emergency department based randomized study of oxycodone/ acetaminophen versus acetaminophen alone for patients with acute musculoskeletal pain refractory to ibuprofen
- Trial name
- NCT04122443
- Testing
- Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Montefiore Medical Center
Arthroplasty Complications, Arthroplasty, Replacement, Knee
Kinesiotape for Edema After Bilateral Total Knee Arthroplasty
The purpose of this study is to determine if kinesiotaping for edema management will decrease post-operative edema in patients with bilateral total knee arthroplasty.
- Trial name
- NCT05013879
- Testing
- Kinesio(R)Tape for edema control
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Montefiore Medical Center
Aromatherapy, Anxiety
Aromatherapy With Lavender as Anxiolysis Prior to Cataracts Surgery
The purpose of this study is to assess the validity of lavender aromatherapy as a method of anxiolysis prior to a cataract surgery, and to see if this effect will extend intraoperatively to minimize patients' intraoperative…
- Trial name
- NCT05708066
- Testing
- Lavender Aromatherapy, Non-scented Tab
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
GERD, Morbid Obesity
Management of Reflux After Sleeve Using Stretta
Gastroesophageal reflux disease (GERD) is a frequently seen entity after sleeve gastrectomy. Management of GERD after sleeve is difficult given limited treatment modalities.
- Trial name
- MaRSS (NCT02637713)
- Testing
- Stretta, Radiofrequency (RF) Energy to the LES (Stretta Procedure)
- Where
- 13 sites in United States
- Volunteers
- 5 people
- Sponsor
- Montefiore Medical Center
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control
To evaluate the efficacy of virtual reality analgesia (VRA) for pediatric patients undergoing Botulinum toxin injections (BTI) for spasticity management.
- Trial name
- PEDSPAINVR (NCT03480724)
- Testing
- Google Cardboard VRA, Oculus Rift VRA
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Montefiore Medical Center
Radiation Dermatitis
Topical Steroids & Bacterial Decolonization for Radiation Dermatitis
The purpose of this study is to determine whether bacterial decolonization of the nares and skin, topical steroid therapy, or a combination of the two regimens prior to treatment with radiotherapy (RT) for breast and head and…
- Trial name
- NCT05505214
- Testing
- Bacterial decolonization, Mometasone furoate 0.1% cream, Bacterial decolonization and Mometasone furoate 0.1% cream
- Where
- United States
- Sponsor
- Montefiore Medical Center
Nephrolithiasis
Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.
There are two options for postoperative pain management: opioid and non-opioid analgesia. Pain outcomes will be compared in patients undergoing ureteroscopy and percutaneous nephrolithotomy by randomly administering opioid and…
- Trial name
- PO-NOA (NCT03584373)
- Testing
- Ketorolac Oral Tablet [Toradol], Acetaminophen, Oxycodone Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- Montefiore Medical Center
Substance Use
Regional Partnership for Pregnant Women at Risk of Substance Misuse and Their Newborns
This study recruits pregnant women and new mothers who are at risk of substance use concerns during pregnancy or delivery. These women are followed for 6 months and randomized into two groups; they may receive services as usual…
- Trial name
- NCT03735212
- Testing
- Enhanced Services
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Lung; Node
Investigating Incidental Pulmonary Nodules in Underserved Communities
The study team hypothesizes that incidentally discovered pulmonary nodules are often under captured and/or not surveilled in accordance with published guidelines in the Montefiore Health System, which cares for a large proportion…
- Trial name
- NCT05738031
- Where
- United States
- Sponsor
- Montefiore Medical Center
Radiation Dermatitis
Bacterial Decolonization to Prevent Radiation Dermatitis
The purpose of this study is to determine whether bacterial decolonization of the nares and skin prior to treatment with radiotherapy (RT) for patients with cancers of the head and neck or breast, can prevent high-grade radiation…
- Trial name
- NCT03883828
- Testing
- Chlorhexidine gluconate solution, Mupirocin Ointment
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Montefiore Medical Center
Hidradenitis Suppurativa
Optimizing Intralesional Triamcinolone Dosing for Hidradenitis Suppurativa
Currently, there is limited evidence showing increased resolution of HS flares with higher doses of intralesional triamcinolone (ILTAC) as well as a difference in side effect profile between the doses.
- Trial name
- NCT04582669
- Testing
- Intralesional Triamcinolone 10 mg/mL, Intralesional Triamcinolone 20 mg/mL, Intralesional Triamcinolone 40 mg/mL
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Breast Discharge Infected, Intraductal Papilloma of Breast
Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients With Pathologic Nipple Discharge
In this prospective clinical trial, patients who sign an approved informed consent for ductoscopy to assess etiology of Pathologic nipple discharge (PND) will be enrolled in the study.
- Trial name
- NCT01901562
- Testing
- Ductoscopic papillectomy
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Montefiore Medical Center
Breast Cancer, Ductal Carcinoma in Situ
Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer
The purpose of this study is to examine the genetic material called microRNA of three types of specimens from women with breast cancer.
- Trial name
- NCT02127073
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Montefiore Medical Center
Hiv, Aids
Reducing Time to Spaced-out Appointments for Newly-diagnosed People Living With HIV
The objectives of this study are to pilot test the effect of reducing time to spaced-out appointments from 18 to 6 months for newly-diagnosed people living with HIV (PLWH) in Rwanda who have initiated antiretroviral therapy…
- Trial name
- NCT04567693
- Testing
- Early spaced-out appointments
- Where
- Rwanda
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Bariatric Surgery Candidate
Intraoperative Methadone for Postoperative Pain Control
To compare patient pain perception and satisfaction as well as opioid-related side effects during inpatient and outpatient care when undergoing bariatric enhanced recovery after surgery protocols with and without methadone.
- Trial name
- NCT05845359
- Testing
- Methadone
- Sponsor
- Montefiore Medical Center
Mobile Health, Asthma
Implementing, a Mobile Health Application for HIV Infected and Uninfected Women With Co-morbidities in the Outpatient Setting
This is a pilot study conducted at the Bronx MWCCS Clinical Research Site in the Bronx, NY. We will recruit 60 individuals with coexisting asthma and/or Type 2 DM from this cohort.
- Conditions
- Mobile Health, Asthma, Diabetes Mellitus
- Trial name
- NCT04810260
- Testing
- Use mobile health app (WellXcel) to increase knowledge
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Montefiore Medical Center
Ventricular Tachycardia
Comparison of Ventricular Tachycardia Ablation Strategies in Patients With Ischemic Cardiomyopathy
This is a prospective multicenter randomized open-label study aiming to assess whether endocardial or endocardial-epicardial ablation is superior to the standard approach (i.e., Antiarrhythmic drugs) in achievement of long-term…
- Trial name
- EPI-VT (NCT04512911)
- Testing
- Endocardial ablation, Endocardial- Epicardial ablation, Antiarrhythmic medications
- Where
- United States
- Sponsor
- Montefiore Medical Center
Distension, Gas Bloat Syndrome
Misoprostol for Bloating and Distension
Symptoms of bloating, abdominal distension, and constipation are common in patients with cirrhosis. These symptoms may be explained by disease-associated effects in gastrointestinal physiology, as well as medication side-effects.
- Conditions
- Distension, Gas Bloat Syndrome, Constipation
- Trial name
- NCT04768010
- Testing
- Misoprostol
- Sponsor
- Montefiore Medical Center
Asthma, Asthma Attack
ASTHMAXcel Emergency Department Study
This protocol focuses on Phase 1 of a planned two-phase research project. Phase 1 aims to test and adapt a prototype ASTHMAXcelED application for the ED.
- Trial name
- ASTHMAXcel (NCT05013073)
- Testing
- ASTHMAXcel ED Application
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center