Clinical trials: sponsored by NYU Langone Health
Coronary Artery Disease, Cognitive Impairment
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial
The ISCHEMIA-HF trial will randomize participants with multivessel coronary artery disease (CAD) with ejection fraction (EF) ≤40% in a 1:2:2 fashion to guideline-directed medical therapy (GDMT):coronary artery bypass grafting…
- Conditions
- Coronary Artery Disease, Cognitive Impairment, Heart Failure
- Trial name
- ISCHEMIA-LVD (NCT06566183)
- Testing
- Guideline-directed medical therapy (GDMT), Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI).
- Where
- 6 sites in United States, Brazil and 4 more
- Volunteers
- 1,200 people
- Sponsor
- NYU Langone Health
Chronic Back Pain
The Effect of Yoga Practice on Chronic Back Pain
Chronic low back pain is notoriously difficult to treat and is a primary contributor to lost work days and excessive health expenditures, and whose treatment has, in part, contributed to the opioid crisis.
- Trial name
- NCT04270617
- Testing
- Yoga program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Carcinoma Breast
Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy
The purpose of the study is to evaluate whether a caffeine-based cream can reduce the rates of reconstructive complications in patients with tissue expander based reconstruction requiring post-mastectomy radiation therapy when…
- Trial name
- ReDCoAT (NCT03768492)
- Testing
- Caffeine anhydrous 5% added to Lipoderm Cream Base., Lipoderm Cream Base
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
SUDEP
Risk Factors for Sudden Unexplained Death in Epilepsy
The main purpose of this study is to develop a North American registry for SUDEP cases; requesting family members of epilepsy patients who died suddenly of unclear causes (SUDEP) to contact the study team.
- Trial name
- SUDEP (NCT01662453)
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hirschsprung Disease
Hirschsprung Disease Genetic Study
Hirschsprung disease is a genetic condition caused by lack of nerve cells in varying lengths of the intestines. This study will investigate the complex genetic basis of the disease, which involves multiple interacting genetic…
- Trial name
- NCT00478712
- Testing
- Identification of genetic causes of Hirschsprung Disease
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pre-Frail Older Adults
Pharyngeal Exercise (Plus Protein)
The swallowing muscles are prone to decreased strength and function as part of the natural aging process which can lead to difficulty swallowing, malnutrition, and frailty.
- Trial name
- PE(PP) (NCT05963113)
- Testing
- Pharyngeal Swallowing Exercises, Protein Supplementation, MRI
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Apraxia of Speech
Using tDCS in Speech-based Stroke Rehabilitation
The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation.
- Trial name
- NCT03452202
- Testing
- Soterix 1x1 line tDCS low-intensity stimulator
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Lung Cancer Diagnosis, Colorectal Cancer (Diagnosis)
Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs
The objective of the pragmatic trial to test the effectiveness of an existing, ongoing clinical service, the VA National TeleOncology program (NTO), a multilevel telehealth population health management program.
- Conditions
- Lung Cancer Diagnosis, Colorectal Cancer (Diagnosis), Prostate Cancer Diagnosis, Breast Cancer Diagnosis
- Trial name
- NCT06559059
- Testing
- National TeleOncology
- Where
- 5 sites in United States
- Volunteers
- 1,800 people
- Sponsor
- NYU Langone Health
Hypertension (HTN)
Actions to Decrease Disparities in Risk and Engage in Shared Support for Blood Pressure Control (ADDRESS-BP) in Blacks
To use practice facilitation (PF) + community health worker (CHW) facilitation as a practical and sustainable implementation strategy to support the implementation and evaluation of three multi-level evidence-based interventions…
- Trial name
- NCT05208450
- Testing
- Practice support And Community Engagement (PACE)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- NYU Langone Health
Maternal Care
Holistic Care Partner Program Feasibility and Acceptability
The study aims to build on the knowledge of the United States' ongoing maternal health crisis for Black birthing people. The study team will take a holistic focused approach to build on the experiences of Black women perinatal…
- Trial name
- NCT06520566
- Testing
- Holistic care partner perinatal nurse navigation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Food Protein-Induced Enterocolitis Syndrome
Immunologic Basis of Food Protein-Induced Enterocolitis Syndrome
This is a phase I multicenter clinical trial that aims to find the optimal dose for conducting a novel low-dose, multi-day oral food challenge (OFC) protocol for diagnosing food protein-induced enterocolitis syndrome (FPIES).
- Trial name
- INFINITY (NCT06683521)
- Testing
- Supervised Low-Dose Oral Food Challenge (OFC), At-Home Low-Dose Oral Food Challenge (OFC), Supervised High-Dose Oral Food Challenge (OFC)
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- NYU Langone Health
Caregiver-Child Interaction, Child Learning
PlayReadVIP in Family Child Care
This study uses a mixed-methods, single-group pretest-posttest design to evaluate (1) implementation outcomes (acceptability, adoption, fidelity) and (2) preliminary changes associated with delivery of the adapted PlayReadVIP…
- Trial name
- NCT07489079
- Testing
- PlayReadVIP
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Total Knee Arthroplasty
Persona MC vs PS RCT With ROSA
A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system.
- Trial name
- NCT05391828
- Testing
- Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design, Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
HIV Prevention, Wellbeing
Initiative for Chinese Sex Workers to Promote Wellbeing and Improve HIV Prevention by Reducing intersEctional Stigma
During the development phase (Aim 1), investigators will use a community-driven process to further refine a preliminary intervention design that was developed based on previous research.
- Trial name
- INSPIRE (NCT07103525)
- Testing
- INSPIRE Initiative, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Early Psychosis
R33: Levetiracetam in Early Psychosis
This is a 12-week study of levetiracetam added to a second generation antipsychotic in early psychosis patients who have been ill for less than 5 years and continue to experience psychotic symptoms despite at least 8 weeks of…
- Trial name
- NCT04317807
- Testing
- Levetiracetam Pill
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- NYU Langone Health
Cardiometabolic Disease
Building Access to Food Through Systems and Solidarity (BASIS): A Subsidized and Culturally-adapted Produce Box Program for Immigrant Communities of Brooklyn, NY
The goal of this study is to improve diet and social cohesion among Chinese American families living in New York City (NYC) through a program that provides whole grains and legumes, builds ethnic identity, and fosters family…
- Trial name
- NCT07076251
- Testing
- Family Box program
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Epilepsy
NYU Epilepsy Self-Management Study
The investigators will conduct two-arm randomized controlled trials (RCTs) comparing effects of UPLIFT vs. enhanced usual care and PACES vs.
- Trial name
- NCT07087821
- Testing
- UPLIFT, PACES, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- NYU Langone Health
Exposure to World Trade Center Dust
NYU/Bellevue WTC Health Impacts Research Registry
The American Red Cross has funded a multidisciplinary, comprehensive evaluation and treatment program for target individuals with suspected World Trade Center (WTC)-related health problems.
- Trial name
- NCT00404898
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Trauma-related PTSD
Considering Racial and Acculturation Stress in Addressing Trauma
Investigators plan to offer two evidence based interventions - Trauma Focused Cognitive Behavioral Therapy (CBT) (TF-CBT) and Trauma Systems therapy (TST) to traumatized children and their families.
- Trial name
- NCT05974176
- Testing
- Trauma Focused CBT (TF-CBT), Trauma Systems therapy (TST)
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis
Noninvasive Vagal Nerve Stimulation
Growing evidence suggests that vagal nerve stimulation (VNS) may be novel and effective in the management of the symptom burden of multiple sclerosis (MS) potentially by reducing inflammation and emotional distress, therefore…
- Trial name
- VANISH-MS (NCT06816004)
- Testing
- Remotely Supervised Transcranial Direct Current Stimulation (RS - tDCS), Remotely Supervised Transcutaneous Auricular Vagus Nerve Stimulation (RS - taVNS), Remotely Supervised Transcutaneous Cervical Vagus Nerve Stimulation (RS - tcVNS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.