Clinical trials: sponsored by NYU Langone Health
Acute Decompensated Heart Failure
Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure
This is a prospective cohort study for 50 patients admitted to the cardiac care unit requiring clinically-indicated diuretic therapy for congestive heart failure.
- Trial name
- NCT05240651
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Renal Cancer
Advanced Diffusion Imaging in Renal Cancer Patients
The objective of this study is to apply advanced diffusion imaging in a two-pronged assessment of renal mass patients: (1) characterization of lesion malignancy and subtype, and (2) prediction of renal function stability or…
- Trial name
- NCT06116253
- Testing
- Magnetic Resonance Imaging (MRI) Scan, Tc-99m Pentetate
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- NYU Langone Health
Neurofibromatosis Type 1
Gait in Young Children With NF1
The objective of this study is to develop office-based tools to quantify gait in young children with NF1 that reflect overall gross motor impairment and predict future gross motor difficulties.
- Trial name
- NCT07564622
- Volunteers
- 56 people
- Sponsor
- NYU Langone Health
Child Mental Health
Families, Children and Teachers Thriving Together
The current study examines the impact of ParentCorps in high-poverty district schools in New York City (NYC). The study is conducted within the context of the NYC Department of Education (DOE) Pre-K Thrive initiative.
- Trial name
- NCT04276363
- Testing
- Thrive Professional Learning plus ParentCorps, Thrive Professional Learning only, Inspire Professional Learning
- Where
- United States
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Enteric Hyperoxaluria
Gut Kidney Axis in Enteric Hyperoxaluria
40 subjects with a confirmed diagnosis of IBD or >6 months post-RYGB with a diagnosed USD event or kidney stone on imaging within the past three years and 40 healthy controls will be administered a high oxalate diet on Days 0-3…
- Trial name
- NCT05124886
- Testing
- Moderately High Oxalate (MOx) Diet
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Substance Use
Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)
The purpose of this trial is to test the efficacy of a collaborative care intervention to address opioid- and/or stimulant-involved polysubstance use in adult primary care patients with moderate to severe substance use disorders…
- Trial name
- NCT06116266
- Testing
- Education and support for primary care providers (PCPS), Nurse Care Manager (NCM) visits, Addiction specialist consultant
- Where
- 8 sites in United States
- Volunteers
- 301 people
- Sponsor
- NYU Langone Health
Alzheimer Disease, Major Depressive Disorder
Aβ Dynamics in LLMD
This study will examine the biological factors that may modulate the relationship between depression and the development of Alzheimer's disease (AD).
- Trial name
- NCT05004987
- Testing
- Escitalopram Oxalate
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Overdose, Substance Use
Permanent Supportive Housing Overdose Prevention+ Study
This community-partnered study examines a technical assistance intervention designed to help permanent supportive housing agencies implement evidence-based practices to prevent tenant overdose and improve tenant health.
- Trial name
- POP+ (NCT07214519)
- Testing
- TA Intervention
- Where
- United States
- Volunteers
- 2,940 people
- Sponsor
- NYU Langone Health
Multiple Myeloma, Large B-cell Lymphoma (LBCL)
Emapalumab Prophylaxis of Bispecific T-Cell Engagers (BiTEs) Associated CRS and ICANS
The purpose of this study is to evaluate emapalumab as a prophylactic therapy in preventing cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) in patients with hematologic…
- Trial name
- NCT07567014
- Testing
- Emapalumab
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Altius Peripheral Nerve Stimulation in Amputees After TMR/RPNI
This is a single-center, prospective, within-subject study. This study seeks to enroll a total of 32 prospective subjects who will undergo surgical implantation of the FDA-approved Altius® system.
- Trial name
- NCT07571239
- Testing
- Surgical Implantation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Overdose
Permanent Supportive Housing Overdose Prevention
Permanent supportive housing (PSH), the gold standard intervention for ending chronic homelessness, has expanded rapidly across the U.S. in recent years.
- Trial name
- POP (NCT05786222)
- Testing
- CSH-Delivered Overdose Prevention Support
- Where
- United States
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hematologic Malignancy
A Phase II Single-arm Study of Total Body Irradiation With Linac Based VMAT and IGRT
Single institution study of safety of linac based VMAT TBI for myeloablative treatment in hematologic malignancies.
- Trial name
- NCT04509765
- Testing
- Linac Based VMAT TBI
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Smoking
Integrating Financial Coaching and Smoking Cessation Coaching
This study conduct a two-arm, parallel-group randomized controlled trial. The study will recruit and randomize 900 smokers (n=450 per arm) to either: (1) Control: Standard Smoking Cessation Counseling or (2) Intervention…
- Trial name
- NCT05154669
- Testing
- Financial counseling, Nicotine Replacement Therapy Agent - Patches, Nicotine Replacement Therapy Agent - Lozenges
- Where
- United States
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Families With Infants
HealthySteps + PlayReadVIP
This study aims to investigate the effectiveness and implementation outcomes for the integration of two evidence-based practices and interventions (EBPIs) within pediatric primary care settings: HealthySteps (HS), which provides…
- Trial name
- NCT06941337
- Testing
- HealthySteps (HS), PlayReadVIP
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Lumbar Stenosis
The Prevalence of Directional Preference in the Lumbar Stenosis Population
This will be a prospective cohort observational study observing patients with low back pain with leg pain who present for outpatient physical therapy care at Rusk Rehabilitation at NYU Langone Ambulatory Care Lake Success.
- Trial name
- NCT07007663
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- NYU Langone Health
Genitourinary Syndrome of Menopause (GSM)
Via, a Hyaluronic Acid (HLA) Based Vaginal Moisturizer Study
This study aims to evaluate whether the administration of vaginal estrogen along with Via, a hyaluronic acid-based vaginal moisturizer, offers superior relief from symptoms of genitourinary syndrome of menopause (GSM) in the…
- Trial name
- NCT07038070
- Testing
- Vaginal estrogen tablet, Via Solv Wellness (Hyaluronic Acid Therapy)
- Where
- United States
- Sponsor
- NYU Langone Health
Healthy
Gut Microbiome Pill
The purpose of this study is to evaluate the safety and efficacy of a 3D-printed ingestible pill designed to sample microbiota from the GI tract, focusing on the ability to collect data also from the small intestine.
- Trial name
- NCT07243756
- Testing
- 3D-printed ingestible pill
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Traumatic Brain Injury
Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.
This project will examine if computerized cognitive remediation will improve working memory and attention in 25 adults with a mild, moderate, or severe brain injury and compare their cognitive performance to the control group of…
- Trial name
- NCT04349852
- Testing
- BrainHQ Cognitive Training Modules, BrainHQ People Skills Modules
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Airway Disease, Barrett Esophagus
Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)
A majority of Fire Department of New York (FDNY) World Trade Center (WTC) exposed rescue and recovery workers developed gastroesophageal reflux disease (GERD), a risk factor for Barrett's Esophagus (BE) and subsequent esophageal…
- Conditions
- Airway Disease, Barrett Esophagus, Gastroesophageal Reflux Disease
- Trial name
- NCT05216133
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Craniofacial Surgery
Effect of Novel High Dissolving Transitional Foods
This is a prospective comparative study, where patients who meet inclusion criteria undergoing a craniofacial procedure will either be provided with novel high dissolving transitional foods for use in the post-operative period…
- Trial name
- NCT06522958
- Testing
- High Dissolving Transitional Food
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- NYU Langone Health