Clinical trials: sponsored by NYU Langone Health
Diet Habit
Building Access to Food Through Systems and Solidarity
BASIS aims to implement a whole-of-community intervention in Brooklyn for improving diet and the social and /built environments for English-, Chinese-, Spanish-, and Bangla-speaking communities.
- Trial name
- BASIS (NCT05381766)
- Testing
- CSA Model
- Where
- United States
- Volunteers
- 3,200 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Optimizing Timing of rhPSMA-7.3 (18F) for Assessing Site(s) of Recurrent Disease Following Radical Prostatectomy
All men following Radical Prostatectomy (RP) at NYU Langone Health undergo routine prostate specific antigen (PSA) testing in order to identify disease recurrence.
- Trial name
- NCT05678322
- Testing
- 18F-Labeled Positron Emission Tomography (PET) Diagnostic Agent, PET MRI Imaging
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- NYU Langone Health
Sedative During Endoscopy
Implementing Virtual Reality (VR) to Reduce Sedation
The study is a prospective pilot patients aged 21 to 65 undergoing screening colonoscopy or diagnostic upper endoscopy. Patients are administered minimal sedation (2 mg of Versed and 25 mg of Fentanyl) and are given Virtual…
- Trial name
- NCT06349564
- Testing
- Pico 4 Enterprise headset with noise cancelling headphones
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Myocardial Infarction
Heart Attack Research Program- Imaging Study
The HARP study is a multi-center, diagnostic observational study employing standardized imaging protocols in patients with MINOCA (MI with Non Obstructive Coronary Arteries) to determine the underlying diagnosis in each…
- Trial name
- HARP (NCT02905357)
- Testing
- OCT, CMR
- Where
- 20 sites in United States, Canada and 1 more
- Volunteers
- 450 people
- Sponsor
- NYU Langone Health
Obesity
Comparison of Obesity Alleles Among Diverse Demographic Patients
This proposal is designed to (1) establish the feasibility of a research strategy for discovering ethnic differences in the frequency of genotypes in patients after bariatric surgery and (2) perform a preliminary evaluation of…
- Trial name
- NCT01396096
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- NYU Langone Health
Multiple System Atrophy, Parkinson Disease
UB-312 in Patients With Synucleinopathies
This is a Phase 1b study to determine the safety, tolerability, and immunogenicity of UB-312 in participants with multiple system atrophy (MSA), and in participants with Parkinson's disease (PD).
- Trial name
- NCT05634876
- Testing
- UB-312 Injection
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Polysubstance Abuse, Posttraumatic Stress Disorder
Adaption of the STAIR-NT Trauma Intervention for Polysubstance Populations
During this 36-month R34 trial, eight study phases are proposed to adapt an evidence-based post traumatic stress disorder (PTSD) intervention (STAIR-NT) and layer it into a methadone maintenance treatment (MMT) program (START…
- Trial name
- NCT06307340
- Testing
- Skills Training in Affective and Interpersonal Regulation with Narrative Therapy (STAIR-NT), Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- NYU Langone Health
End Stage Kidney Disease
Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease
16 individuals with hemodialysis-dependent end stage kidney disease will receive 16 days of a potassium-containing salt-substitute and 16 days of standard table salt in random order.
- Trial name
- NCT05558267
- Testing
- Standard Table Salt, Salt Substitute
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Evaluation of Tumor Control Based on Serial Multiparametric MRI and Post-Treatment Biopsies For Patients Treated With Dose Intensification to the Dominant Intra-Prostatic Lesion (DIL) Using Ultra-Hypofractionated, MR-Guided Radiotherapy
The purpose of this study is to assess the impact of this MR-guided radiotherapy on tumor control of the dominant intraprostatic lesion among patients with intermediate risk prostate cancer.
- Trial name
- NCT06542757
- Testing
- 1.5 T Elekta Unity MR-Linac system, Hydrogel rectal spacer (SpaceOAR)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- NYU Langone Health
Opioid Use Disorder, Cigarette Smoking
E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
The purpose of this an open-label, randomized controlled trial study is to compare the effectiveness of electronic cigarettes (e-cigarettes/e-cigs) versus telehealth motivational counseling with combination nicotine replacement…
- Trial name
- NCT05722561
- Testing
- Telehealth Motivational Counseling, Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).
- Where
- 2 sites in United States
- Volunteers
- 302 people
- Sponsor
- NYU Langone Health
Self-Control
Stress & Self-Control Costs
Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms…
- Trial name
- NCT05795179
- Testing
- Cold-Pressor Task (CPT), Trier Social Stress Test (TSST), Modified Non-Stress CPT
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Non-small Cell Lung Cancer With STK11/LKB1 Mutation
Daratumumab in STK11 Mutated NSCLC
This is a single-arm study of daratumumab in metastatic non-small cell lung cancer (NSCLC) patients with an STK11/LKB1 mutation.
- Trial name
- NCT05807048
- Testing
- Daratumumab and Hyaluronidase-fihj, Pre-Intervention Medication, Post-Intervention Medication
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Type 2 Diabetes
Implementing an Effective Diabetes Intervention Among Low-Income Immigrants
The goal of this IDEAL project is to examine the effectiveness and implementation process of the video-based Diabetes Self-Management Education and Support (DSMES) + community health worker (CHW) (hereafter: "IDEAL") intervention…
- Trial name
- IDEAL (NCT06319703)
- Testing
- Diabetes Self-Management Education and Support (DSMES) Videos, Community Health Worker Support (CHW)
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- NYU Langone Health
Melanoma
A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma
This is a Phase II, open-label, single arm study. The study will consist of an assessment of the safety and tolerability of tocilizumab administered concurrently at 4 mg/kg every 6 weeks for 5 doses in combination with ipilimumab…
- Trial name
- NCT03999749
- Testing
- Ipilimumab, Nivolumab, Tocilizumab
- Where
- 4 sites in United States
- Volunteers
- 71 people
- Sponsor
- NYU Langone Health
High-grade Glioma
Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac
This is a phase 1 study to examine the safety and tolerability of biology-guided dose intensified hypofractionated radiation therapy (RT) using MR-Linac for patients with high grade glioma (HGG).
- Trial name
- INSIGHT MRL (NCT07457307)
- Testing
- MR-Linac System, Radiation Therapy, Temozolomide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Deafness With a Cochlear Implant
Stimulating the Cochlear Apex Without Longer Electrodes
The most common cochlear implant intervention provides an electrode array that stimulates less than half of the length of the cochlea, leaving the regions which represent lower frequencies in the normally functioning ear…
- Trial name
- NCT06901674
- Testing
- Modified surgical approach, Cochlear Nucleus CI632 cochlear implant
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Colon Cancer, Peripheral Neuropathy
Cryotherapy & Oxaliplatin
The primary objective of this study is to determine if cryotherapy is beneficial to patients with colon cancer who are receiving oxaliplatin in the prevention of developing chemotherapy induced peripheral neuropathy.
- Trial name
- NCT06281925
- Testing
- Cryotherapy Gloves
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Prostatectomy
Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery
The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain.
- Trial name
- NCT06477133
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- NYU Langone Health
Cardiovascular Diseases
A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)
This study will investigate the acceptability and efficacy of 12 weeks of: Smart-device app-based (MyZone) Asynchronous Virtual, Synchronous Virtual, and in-person aerobic training in individuals at risk for Cardiovascular…
- Trial name
- NCT06931470
- Testing
- In-person supervised exercise sessions, Virtual classes (live-streamed sessions), Self-directed aerobic exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Calorie Consumption
Dietary and Cognitive Effects of Food Ads Posted by TikTok Influencers
Randomized and controlled experimental study to evaluate how influencer food ads on TikTok affect calorie purchases among youth (ages 10-13).
- Trial name
- NCT05777486
- Testing
- TikTok Ads - With Food, TikTok Ads - Without Food
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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