Clinical trials: sponsored by NYU Langone Health
Inflammatory Bowel Diseases
Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease
This study aims to determine if improved risk stratification tools and interventions to mitigate malnutrition reduce postoperative risk in patients undergoing elective or emergent resection surgery for inflammatory bowel disease…
- Trial name
- NCT06309017
- Testing
- Nutrition specialist, Ensure Surgery Immunonutrition shakes
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
IBS - Irritable Bowel Syndrome
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
This study will serve as a pilot randomized controlled trial to assess the feasibility of Psilocybin-Assisted Psychotherapy (PAP) in Treating Irritable Bowel Syndrome (IBS).
- Trial name
- NCT06760533
- Testing
- Psilocybin 25 mg, Psychotherapy Treatment Session, Niacin 100 mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Mental Disorder in Adolescence
Adolescent Digital Mental Health-Kenya Effectiveness
This study seeks to respond to the growing burden of adolescent mental health disorders and urgent preventive service needs in Kenya by studying the effectiveness of a digital health intervention- mobile health (mHealth) Toolkit…
- Trial name
- NCT06403813
- Testing
- mHealth Toolkit for Screening & Empowering Lives of Youth (mSELY-A) for Adolescents, mHealth Toolkit for Screening & Empowering Lives of Youth (mSELY-P) for Parents, Control Tooklit
- Where
- Kenya
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Takotsubo Syndrome
Autonomic Modulation in Takotsubo Syndrome
This is a minimal risk case-controlled single arm intervention study, including 10 patients with a prior history of takotsubo and 10-age and sex matched healthy controls.
- Trial name
- NCT03324529
- Testing
- Tako Breath
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
ACL Reconstruction
Effect of Internal Brace on Outcomes Following ACL Reconstruction With BTB Autograft
The purpose of this study is to assess Anterior Cruciate Ligament (ACL) healing through analyzing clinical, radiographic, functional and patient-reported outcomes following ACL reconstruction with bone-tendon-bone autograft with…
- Trial name
- NCT06542705
- Testing
- Arthrex Internal Brace, ACL Reconstruction
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
Prosthetic-joint Infection
The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee
The purpose of this study is to determine whether probiotics in addition to standard of care (SOC) can improve immunological markers following treatment for prosthetic joint infection (PJI).
- Trial name
- NCT06919913
- Testing
- Culturelle Digestive Daily Probiotic Capsule
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- NYU Langone Health
Deafness
Novel Coding Strategies for Children With Cochlear Implants
The purpose of this study is to understand performance with a cochlear implant. The long-term goals of this research are to improve sound perception with cochlear implants and to better understand the functioning of the auditory…
- Trial name
- NCT05203302
- Testing
- Single-Electrode Pulse Train, Modulation Detection Threshold (MDT) and Gap Detection Tasks, Sound coding strategy.
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Presbyphonia
Creatine Supplementation for Improved Voice Performance in the Elderly
The primary objective of this study is to determine if creatine supplementation improves acoustic, auditory perceptual, physiologic, and patient-reported outcome measures in patients over 65 years of age.
- Trial name
- NCT05856916
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Total Knee Arthroplasty
Utilization of a 3D Printed Mechanical Balancer During Total Knee Arthroplasty (TKA)
The aim of this study is to test a 3D-printed mechanical balancer in a clinical setting during surgery to further evaluate the utility of the device.
- Trial name
- NCT06654661
- Testing
- 3D-Printed Mechanical Balancer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Familial Dysautonomia
Pilot Study of Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia
This is a pilot open-label study to evaluate the feasibility of conducting a clinical trial using sublingual dexmedetomidine sublingual film to treat hyperadrenergic autonomic crises in patients with Familial Dysautonomia at…
- Trial name
- NCT06128356
- Testing
- Dexmedetomidine Sublingual
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- NYU Langone Health
Hip Arthropathy
Optimized MRI of Patients With Hip Arthroplasty
This is a single-center single-arm clinical trial with a paired design which compares the effectiveness of 3T MRI with (modified) and without (standard) radiofrequency pulse polarization optimization in reducing metal-related…
- Trial name
- NCT04875884
- Testing
- Modified MRI
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Cardiovascular Disease, Alcohol Use Disorder
Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk
The purpose of this research study is to investigate if a personalized intervention including parts such as navigation (focus on patient outreach efforts, missed and completed encounters), personalization (individual health…
- Conditions
- Cardiovascular Disease, Alcohol Use Disorder, HIV Risk, Substance Use Disorders
- Trial name
- NCT05828849
- Testing
- Navigation, compensation, and personalization
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Geriatric Hip Fracture
Nutritional Supplementation in Geriatric Hip Fractures
This study is a randomized controlled trial comparing outcomes between geriatric hip fractures who received a commercially available (XR RecoveryTM, Salt Lake City Utah) peri-operative nutritional supplement for three weeks…
- Trial name
- NCT06773000
- Testing
- XR™ Recovery Supplement, XR Carbohydrate Loading Supplement
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- NYU Langone Health
Pre Diabetes
Evaluation of an Automated Physician-Directed Messaging on Patient Engagement in the Digital Diabetes Prevention Program
This study aims to understand the effects of automated physician directed messaging on patient engagement in the digital diabetes prevention program (dDPP).
- Trial name
- NCT04773834
- Testing
- Digital diabetes prevention program (dDPP), Adapted dDPP-EHR tool
- Where
- United States
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Genetic Testing
Universal Genetic Testing for Cancer Risk Reduction
The purpose of this research study is to see if offering genetic testing for cancer-related genes is feasible and acceptable for patients presenting for gynecology clinic visits, instead of needing to see specialized providers or…
- Trial name
- NCT06926816
- Testing
- Natera® Empower™ hereditary cancer panel test, Specialist Referral
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alzheimer's Disease Related Dementia, Alzheimer Disease
ED-LEAD: Emergency Departments Leading the Transformation of Alzheimer's and Dementia Care
The purpose of this study is to improve the care of persons living with dementia (PLWD) and their informal care partners by addressing emergency and post-emergency care through different combinations of three PLWD-care partner…
- Trial name
- NCT06079203
- Testing
- Emergency Care Redesign (ECR), Nurse-led Telephonic Care (NLTC), Community Paramedic-led Transitions Intervention (CPTI)
- Where
- United States
- Volunteers
- 19,200 people
- Sponsor
- NYU Langone Health
Overdose
Overdose Prevention Centers and Behavioral Health
The aims of this study are: (Aim 1) Identify sources of heterogeneous impacts of opioid prevention center (OPC) use on non-fatal and fatal overdose risk among individuals with histories of polysubstance use (PSU); (Aim 2)…
- Trial name
- NCT06236087
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- NYU Langone Health
Visual Impairment
Virtual Assistance for Daily Living: Neurophysiological and Functional Effects in Low Vision
This study aims to investigate how visual impairment affects neurophysiological and biomechanical responses during real-world navigation and daily activities, with a focus on the rehabilitative feasibility and impact of assistive…
- Trial name
- NCT07442461
- Testing
- VIS4ION Platform
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Generalized Anxiety Disorder, Social Anxiety Disorder
Level of Physical Activity and Fear Learning
The proposed experimental study will be the first to investigate whether exercise vs. sitting enhances consolidation of extinction learning in adults with high AS and anxiety disorders, and the mechanistic pathways of expectancy…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT05203731
- Testing
- Exercise, Sitting
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- NYU Langone Health
Cardiovascular Disease, Hypertension
Peers and Technology for Adherence, Access, Accountability, and Analytics (PT4A)
Peer-based medication delivery decreases the cost of transportation and the opportunity cost of travel while HIT can support peer activities by facilitating targeted adherence counseling, teleconsultation, synchronization of…
- Trial name
- PT4A (NCT06485700)
- Testing
- Peer Delivery of Medications, Health Information Technology (HIT) Platform
- Where
- 3 sites in Kenya
- Volunteers
- 1,140 people
- Sponsor
- NYU Langone Health
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