Clinical trials: sponsored by NYU Langone Health
Physical Therapy
Efficacy of STABL Virtual Rehabilitation
The purpose of the proposed study is to evaluate the efficacy of STABL rehabilitation vs in-person rehabilitation following meniscectomy or synovectomy.
- Trial name
- NCT05556850
- Testing
- STABL Virtual Rehabilitation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Oropharyngeal Squamous Cell Carcinoma
Lattice-Based Radiotherapy and Chemoimmunotherapy for Oropharyngeal Squamous Cell Carcinoma
This single-arm Phase I/II trial evaluates induction chemoimmunotherapy combined with lattice radiotherapy (LRT) in patients with non-low risk oropharyngeal squamous cell carcinoma and primary tumor ≥3 cm or primary tumor and…
- Trial name
- NCT07428148
- Testing
- Induction Chemo-Immunotherapy, Lattice Radiotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Acute Bronchiolitis
Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis
This study will examine the efficacy of combined nebulized hypertonic saline with chest percussion therapy in patients age 0 to 24 months admitted to the general inpatient pediatrics unit with acute bronchiolitis.
- Trial name
- NCT06441162
- Testing
- Nebulized 3% sodium chloride solution, Chest percussion cups
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- NYU Langone Health
Spinal Deformity
Intraoperative Alignment in Adult Spinal Deformity Surgery
The purpose of this study is to conduct a prospective study which assesses the utility of the ATEC Intraoperative Alignment (IOA) Imaging Platform tool in intraoperative imaging for patients undergoing adult spinal deformity…
- Trial name
- NCT07416565
- Testing
- ATEC IntraOperative Alignment (IOA) Imaging Platform, Standard 36" cassette imaging, EOS radiographs
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Osteoarthritis
Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty
This is a prospective, randomized, controlled, open label, parallel four-arm design, multi-center study to compare different intraoperative interventions in the prevention of acute PJI development.
- Trial name
- NCT04075526
- Testing
- Povidone iodine, Vancomycin powder, Conventional
- Where
- 14 sites in United States
- Volunteers
- 2,129 people
- Sponsor
- NYU Langone Health
Post Traumatic Stress Disorder, Traumatic Brain Injury
Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI
This will be a randomized placebo controlled study to test the efficacy of cannabidiol (CBD) as a treatment for symptoms of post-traumatic stress disorder (PTSD).
- Trial name
- NCT04550377
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Epilepsy
Telephone-Based Support Programs for People With Epilepsy
This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST).
- Trial name
- NCT05082181
- Testing
- UPLIFT (Using Practice and Learning to Increase Favorable Thoughts), BOOST (Bringing Out Our Strength Together)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Breast Cancer
Gradient-Echo Spectroscopic Imaging Study of Saturated Fat and Breast Cancer
The role of fat in breast cancer development and growth has been studied extensively using body mass index, a measure of whole body fatness, and dietary fat intake in a number of epidemiological studies.
- Trial name
- NCT03400215
- Testing
- Diagnostic Breast Cancer Scan, Research Scan for Gradient-echo Spectroscopic Imaging (GSI)
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Substance Use, HIV Prevention
A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs
This study includes finalization of the LINKED social network intervention to improve PrEP and MOUD uptake among people who inject drugs (PWID) in collaboration with an Expert Advisory Board and staff (N=16) at The Sidewalk…
- Trial name
- NCT07409350
- Testing
- LINKED, Group Intervention
- Where
- 3 sites in United States
- Volunteers
- 398 people
- Sponsor
- NYU Langone Health
Delirium Superimposed on Dementia
Study of the Aliviado DSD Caregiving Mastery Program
Delirium superimposed on dementia (DSD) is an acute and serious condition that is common in persons living with dementia (PLWD). Involvement of family caregivers may aid prevention, early detection, and management of DSD.
- Trial name
- NCT05630014
- Testing
- Aliviado DSD Caregiving Mastery Program
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Implant; Complications
Split Chest Breast Neurotization
Several members of the scientific community have suggested that breast neurotization can help return nipple sensation to patients undergoing implant-based breast reconstruction.
- Trial name
- NCT05757778
- Testing
- Sensory Nerve Coaptation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Rotator Cuff Injuries
Telerehabilitation for Shoulder Surgery Recovery
This study aims to evaluate the effectiveness of a telerehabilitation protocol utilizing the Band Connect platform in patient recovery following rotator cuff repair surgery.
- Trial name
- NCT07392502
- Testing
- Band Connect, Physical Therapy
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- NYU Langone Health
Major Depressive Disorder
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33
The purpose of this research study is to determine if application of near infrared energy to the forehead can change blood flow in the brains of people with depression.
- Trial name
- TRIADE-R33 (NCT05573074)
- Testing
- Transcranial Photobiomodulator
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Cardiorespiratory and Vascular Dysfunction, Obstructive Airway Disease
World Trade Center Particulate Matter Induced Cardiorespiratory and Vascular Dysfunction: a MultiOmic Approach (CaRVD)
Particulate matter (PM) associated cardiorespiratory and vascular dysfunction (CaRVD) poses a significant global health burden. The World Trade Center (WTC) destruction on September 11, 2001 led to an intense deposition of…
- Trial name
- NCT05215171
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Cardiovascular Diseases, Coronary Disease
ISCHEMIA-EXTEND (Extended Follow-up)
The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) Extended Follow-up (ISCHEMIA-EXTEND) is the long-term follow-up of randomized, surviving participants in ISCHEMIA.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Coronary Artery Disease, Heart Diseases
- Trial name
- NCT04894877
- Testing
- cardiac catheterization, coronary artery bypass graft surgery, percutaneous coronary intervention
- Volunteers
- 5,391 people
- Sponsor
- NYU Langone Health
Heart Failure
The PURI-HF (Air Purifiers on Heart Failure) Trial
Indoor air pollution and fine mode particulate matter with an aerodynamic diameter smaller than 2.5 micrometers (PM2.5) is a major contributor to global morbidity and mortality, particularly due to cardiovascular disease.
- Trial name
- NCT05230784
- Testing
- AirOk Air Purifier
- Where
- 3 sites in India
- Volunteers
- 255 people
- Sponsor
- NYU Langone Health
Graft Vs Host Disease
Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD
This is a single arm, open label, phase II clinical trial. Adult patients with hematological malignancies undergoing allogeneic HSCT from first- or second-degree haploidentical donor are eligible for the study if they meet the…
- Trial name
- NCT05621759
- Testing
- Cyclophosphamide, Abatacept, Tacrolimus
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Two Fraction Prostate SBRT With DIL SIB
Phase I/Ib, single arm trial of Two-Fraction Stereotactic Body Radiation Therapy (SBRT) with an MRI directed, dominant intraprostatic lesion (DIL), simultaneous integrated boost (SIB) based on genomic classification in the…
- Trial name
- NCT05864196
- Testing
- Two-Fraction Stereotactic Body Radiation Therapy (SBRT)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Environmental Exposure
Assessing and Addressing Community Exposures to Environmental Contaminants
The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting…
- Trial name
- NCT06315140
- Testing
- Nutrition
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alopecia
Evaluating Vibrational Anesthesia in Scalp Platelet Rich Plasma (PRP)
This study is prospective, single-site, randomized split-scalp pilot and survey study of patients at the NYU Skin and Cancer Clinic or the Faculty Group Practice.
- Trial name
- NCT06497764
- Testing
- Vibrational Anesthesia (VA) Device, PRP Treatment
- Where
- United States
- Sponsor
- NYU Langone Health