Clinical trials: sponsored by NYU Langone Health
Heart Failure
The PURI-HF (Air Purifiers on Heart Failure) Trial
Indoor air pollution and fine mode particulate matter with an aerodynamic diameter smaller than 2.5 micrometers (PM2.5) is a major contributor to global morbidity and mortality, particularly due to cardiovascular disease.
- Trial name
- NCT05230784
- Testing
- AirOk Air Purifier
- Where
- 3 sites in India
- Volunteers
- 255 people
- Sponsor
- NYU Langone Health
Alopecia
Evaluating Vibrational Anesthesia in Scalp Platelet Rich Plasma (PRP)
This study is prospective, single-site, randomized split-scalp pilot and survey study of patients at the NYU Skin and Cancer Clinic or the Faculty Group Practice.
- Trial name
- NCT06497764
- Testing
- Vibrational Anesthesia (VA) Device, PRP Treatment
- Where
- United States
- Sponsor
- NYU Langone Health
Traumatic Brain Injury
MENTOR Wellness Program
This randomized trial aims to determine the effectiveness a virtual wellness intervention program in individuals with traumatic brain injury (TBI).
- Trial name
- NCT06148324
- Testing
- MENTOR Program
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- NYU Langone Health
Mild Dementia
Activity Tracking, Care Partner Co-participation, Text Reminders, Instructional Education, Video-Guided Physical Rehabilitation, and Exercise
This is a multi-methods two-arm, crossover, analyst-blinded randomized controlled trial with embedded qualitative interviews, enrolling 50 dyads (older adult-care partner).
- Trial name
- ACTIVE (NCT07321587)
- Testing
- ACTIVE Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Appropriate Use of Language Across Services
Promoting Equitable Access to Language Services in Health and Human Services
This is a community-based study that will engage community and health care stakeholders to develop, implement, and evaluate a Health Literacy (HL)-informed, culturally- and linguistically- sensitive approach to improving language…
- Trial name
- NCT06272110
- Testing
- System level Language Access (LA) intervention
- Where
- 3 sites in United States
- Volunteers
- 17,500 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Prostate Cancer
ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
For this study, unfavorable intermediate risk prostate cancer patients will select whether they are to be treated with the standard of care (SOC) 6 months of Androgen Deprivation Therapy (ADT) in conjunction with stereotactic…
- Trial name
- NCT06397703
- Testing
- Leuprolide, Degarelix or Relugolix, Stereotactic body radiation therapy/radiosurgery (SBRT)
- Where
- United States
- Volunteers
- 392 people
- Sponsor
- NYU Langone Health
Hearing Loss
Pupillary Dilation During Post-Auricular Vagal Nerve Stimulation
The research team will evaluate pupillary dilation from vagal nerve stimulation of Arnold's Nerve, a branch of the vagus nerve, during routine cochlear implantation surgery.
- Trial name
- NCT05870527
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Radiation Exposure
ATTENUATE (rAdpad proTecTion drapE iN redUcing rAdiaTion Exposure) Trial
The purpose of this study is to examine the impact of the RADPAD in proximal operators in a contemporary cardiac catheterization laboratory (CCL), during diagnostic, coronary and structural cardiac catheterization procedures, in…
- Trial name
- NCT06233578
- Testing
- RADPAD
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Chronic Obstuctive Pulmonary Disease
Lung Microbiome and Inflammation in Early COPD
This is a cross sectional case controlled study to assess lung microbiome and inflammation in smokers with and without Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02777879
- Testing
- Bronchoscopy
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- NYU Langone Health
Opioid Use Disorder
Psilocybin for Opioid Use Disorder (OUD)
This is a double-blind, adaptive, 2-stage, multi-site, phase 2 randomized controlled clinical trial designed to evaluate effects of moderate and high dose psilocybin, relative to low-dose psilocybin control, in OUD patients who…
- Trial name
- NCT06796062
- Testing
- Psilocybin
- Where
- 5 sites in United States
- Volunteers
- 480 people
- Sponsor
- NYU Langone Health
Pulmonary Embolism
Nudging Provider Adoption of Clinical Decision Support: Implementation of an EHR-Agnostic Pulmonary Embolism Risk Prediction Tool
The purpose of this study is to examine the impact of the nudge implementation strategy (CDS tool + Nudge) on adoption of guideline-concordant CT ordering for pulmonary embolism (PE) in 10 EDs.
- Trial name
- NCT07249385
- Testing
- Clinical Decision Support (CDS) tool with Nudges
- Where
- 3 sites in United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Head Cancer Neck
Diffusion MRI for Head and Neck Cancer
The proposed study is to investigate the feasibility of using quantitative diffusion MRI (dMRI) methods for accurate and comprehensive assessment of treatment response.
- Trial name
- NCT04251481
- Testing
- PET/MRI with FDG, MRI scan without contrast, MRI with gadolinium
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Tonsillectomy, Infections
Head-Only Draping in Pediatric Tonsillectomy
This single-center, interventional study will compare 30-day postoperative infection rates in pediatric tonsillectomy performed with either head-only draping or traditional full-body draping.
- Trial name
- NCT07347301
- Testing
- Full-Body Surgical Draping, Head-Only Surgical Draping
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Traumatic Brain Injury
tPBM in Older Adults With Traumatic Brain Injury
The purpose of this study is to evaluate the effect of transcranial photobiomodulation (tPBM) in older patients with chronic traumatic brain injury (TBI).
- Trial name
- NCT06956404
- Testing
- Transcranial photobiomodulator (tPBM)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea, Sleepiness
Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness
Obstructive sleep apnea (OSA) is a sleep disorder that is commonly treated using positive airway pressure, yet 50% of patients still experience residual sleepiness after successful therapy.
- Trial name
- STIL TIRED (NCT06698809)
- Testing
- Active tPBM
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
ACL Injury
Internal Bracing Following ACL Reconstruction
The purpose of this study is to assess Anterior Cruciate Ligament (ACL) healing through analyzing clinical, radiographic, functional and patient-reported outcomes following ACL reconstruction with quadriceps graft with and…
- Trial name
- NCT06289153
- Testing
- Arthrex Internal Brace, ACL Reconstruction
- Where
- United States
- Sponsor
- NYU Langone Health
Traumatic Brain Injury
Virtual Reality Treadmill Training in Individuals With Traumatic Brain Injury
This pilot study aims to determine the feasibility of a virtual reality treadmill training intervention in individuals with Traumatic Brain Injury (TBI).
- Trial name
- NCT05721209
- Testing
- C-Mill with AR/VR Guidance, C-Mill without AR/VR Guidance, Zeno 3-Layer Walkway
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Social Anxiety Disorder
Cannabidiol as a Treatment for Social Anxiety Disorder (R61)
The R61 will include two CBD dose levels vs placebo (PBO) and examine potential engagement with two primary targets in a 3-week randomized controlled trial design.
- Trial name
- NCT05571592
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Mild Cognitive Impairment, Alzheimer Dementia
Innate Immunity Stimulation Via TLR9 in Early AD
This single-center, double-blind, placebo-controlled study will recruit in total 39 participants with either Mild Cognitive Impairment due to Alzheimer's disease (MCI) or Mild Alzheimer's disease dementia (mild AD).
- Trial name
- NCT05606341
- Testing
- CpG1018
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- NYU Langone Health
Osteoarthritis, Inflammatory Arthritis
Rotator Cuff Sparing Total Arthroplasty
Design: Prospective, randomized clinical trial, of 120 patients requiring a total shoulder replacement (TSR). Purpose: To collect and evaluate long-term clinical data on patients whose total shoulder replacement (TSR) is…
- Trial name
- NCT01961986
- Testing
- TSR - traditional subscapularis release, TSR - rotator cuff sparing
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- NYU Langone Health
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