Clinical trials: sponsored by NYU Langone Health
ACL - Anterior Cruciate Ligament Rupture, ACL Injury
Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury
The purpose of this single-center, double-blinded randomized control trial with prospective data collection is to assess the ability of platelet rich plasma (PRP) treatment to reduce the level of pro-inflammatory synovial fluid…
- Trial name
- NCT03389685
- Testing
- Platelet Rich Plasma
- Where
- United States
- Sponsor
- NYU Langone Health
Opioid-use Disorder
Buprenorphine Loading in the Emergency Department
Buprenorphine (BUP) is FDA-approved for the treatment of opioid withdrawal and opioid use disorder. Few ED providers have received the necessary DEA registration (aka X waiver) required to prescribe BUP, and urgent appointments…
- Trial name
- NCT04283500
- Testing
- Buprenorphine Naloxone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Type 2 Diabetes
Wearable Sensors and Artificial Intelligence for Carbohydrate Counting
This is a one-group pilot study where Chinese immigrants who are English speaking with T2D from NYU Langone Health and NYU Brooklyn Family Health Center (Sunset Park) will be recruited.
- Trial name
- NCT05335889
- Testing
- eButton, Continuous Glucose Monitoring (CGM)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- NYU Langone Health
Thoracoabdominal Aortic Aneurysms
Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms
The purpose of this study is to evaluate the use of an investigational device called the ValiantTM Visceral Manifold Thoracoabdominal Stent Graft System for the repair of thoracoabdominal aortic aneurysms (TAAA), which is a…
- Trial name
- NCT03246126
- Testing
- Valiant™Thoracoabdominal Stent Graft System
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Hemoglobins, Diagnostic Tests
Electronic Triggers: Messaging After A1C EHR Alert
Studying subjects with HbA1C tests >10 and no follow-up test within 6 months and appointments scheduled in the next 60 days from data run date.
- Trial name
- NCT04869319
- Testing
- MyChart message
- Where
- United States
- Volunteers
- 2,403 people
- Sponsor
- NYU Langone Health
Skin Cancer
SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer
The overall goal of this research is to develop a platform that can increase patient access to expert skin cancer diagnostic services via telemedicine.
- Trial name
- NCT04411810
- Testing
- Nevisense 3.0, Dermlite Cam, Skin biopsy
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Clinical Decision Support
Optimizing the Influenza Clinical Decision Support Tool
The proposed study aims to examine several iterations of the Influenza Best Practice Alert at NYU Langone Health. The goal is to increase ordering of the influenza vaccine through the alert.
- Trial name
- NCT03415425
- Testing
- Current Version of the Influenza Alert, Alternate Modifications of the Influenza Alert
- Where
- United States
- Volunteers
- 25,881 people
- Sponsor
- NYU Langone Health
Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation
Ladarixin With Sotorasib in Advanced NSCLC - Phase II
Study record has been combined with NCT05815173. See NCT05815173 for summary.
- Trial name
- NCT05815186
- Testing
- Sotorasib, Ladarixin
- Where
- 6 sites in United States
- Sponsor
- NYU Langone Health
GastroEsophageal Cancer, Gastric Cancer
A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies
This is an open label, single arm phase II study, to determine the overall response rate for the combination of lenvatinib and pemrolizumab in patients with metastatic gastroesophageal cancer who have progressed on first or…
- Trial name
- NCT03321630
- Testing
- Lenvatinib, Pembrolizumab
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Myelodysplastic Syndromes
A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations
This is an open label, Phase Ib study designed to evaluate the safety, toxicity and biological activity of high dose Vitamin C in bone marrow and peripheral blood when administered as therapy to patients with intermediate or high…
- Trial name
- NCT03433781
- Testing
- Vitamin C
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Total Shoulder Athroplasty
TXA in Anticoagulated Patients Study
This is a randomized, single-blind, single-center study comparing calculated total blood loss, surgical drain output and hematoma formation in anticoagulated patients who receive 2 doses of Tranexamic Acid (TXA) versus control…
- Trial name
- NCT04560010
- Testing
- Tranexamic Acid Injection (TXA)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Keloid Scar
Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid
This is a split-scar study with a target sample size of 20. There are two interventions: fractional erbium:YAG-assisted drug delivery of 5-fluorouracil and fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide.
- Trial name
- NCT04786210
- Testing
- Fractional erbium:YAG-assisted drug delivery of 5-fluorouracil, Fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Surgery Risk Assessment
Clinician Decision Making Regarding Surveillance for Low-risk Intraductal Papillary Mucinous Neoplasms of The Pancreas
The main objective of this study is to determine how physicians make decisions regarding surveillance of Intraductal Papillary Mucinous Neoplasm's (IPMN) of the pancreas.
- Trial name
- NCT06311032
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Arthropathy Shoulder
TXA in Revision Total Shoulder Arthroplasty
This is a phase IV, randomized, single-blind, single-center study comparing calculated total blood loss, surgical drain output and hematoma formation in patients who receive 2 doses of Tranexamic Acid (TXA) versus control group…
- Trial name
- NCT04650698
- Testing
- Tranexamic acid (TXA) injection
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Attention Deficit-Hyperactivity
Study of the Duration and Efficacy of MYDAYIS on Adult ADHD Symptoms and Executive Function Throughout the Day Into the Early Evening
Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric disorder characterized by problems with sustaining attention, organization, planning, procrastination, daydreaming, restlessness, impulsivity and…
- Trial name
- MYDAYIS (NCT03945175)
- Testing
- MYDAYIS
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cystinuria
Registry of Thiola EC Therapy
Thiola EC represents several modifications of Thiola that promise better, more efficacious therapy of cystinuria. First, pill size has changed from 100 mg to 300 mg, meaning that typical pill burden will be reduced from, on…
- Trial name
- NCT05048563
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Opioid Use Disorder
Assessing Optimal XR-Buprenorphine Initiation Points in Jail
The goal of this study is to compare two approaches for commencing pharmacotherapy with injectable buprenorphine for opioid use disorder (OUD) among jail inmates: (1) at the time of admission or (2) shortly before release.
- Trial name
- NCT05481112
- Testing
- Extended-Release Buprenorphine Injection
- Where
- United States
- Sponsor
- NYU Langone Health
Depression
Exercise in Dialysis
The purpose of the proposed clinical trial is to support intradialytic pedal cycling exercise as an intervention and show its effect on depression and how there is a need for more programs to support this.
- Trial name
- NCT05151666
- Testing
- Sunny Health & Fitness Magnetic Mini Exercise Pedal Cycle - SF-B020026 Gray
- Where
- 2 sites in United States
- Sponsor
- NYU Langone Health
Glaucoma
A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma
This pilot study will test the preliminary efficacy and feasibility of an intervention protocol for one method of electric current stimulation, repetitive transorbital alternating current stimulation (rtACS), to treat visual…
- Trial name
- NCT03188042
- Testing
- rtACS Stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- NYU Langone Health
Opioid Dependence, Opioid Abuse
A Pragmatic Trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) Model for Engaging Patients in Opioid Use Disorder Treatment
This pragmatic clinical trial seeks to evaluate the effectiveness of the Consult for Addiction Treatment and Care in Hospitals (CATCH) intervention as a strategy for engaging patients with Opiod Use Disorder (OUD) in addiction…
- Trial name
- CATCH (NCT03611335)
- Testing
- CATCH Interviews
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
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