Clinical trials: open to volunteers, sponsored by NYU Langone Health
Type 2 Diabetes
Adaptive Dietary Intervention (ADI) for Asian Americans With Type 2 Diabetes
The investigators will examine the feasibility, acceptability, and effect of an adaptive dietary intervention over 24 weeks (12-week intervention, 12-week follow-up) among Asian Americans with Type 2 diabetes.
- Trial name
- NCT07278531
- Testing
- Continuous Glucose Monitoring (CGM), Adaptive dietary intervention (GEM)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Problems Related to Social Environment
Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder
Using a stepped-wedge randomized controlled trial, the study will test whether a clinic-level multidimensional intervention conducted in 36 opioid treatment programs (OTPs) will improve clinical decision making, regulatory…
- Trial name
- NCT05675735
- Testing
- Clinic-Level Multidimensional Intervention
- Where
- 4 sites in United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Young Onset Parkinson Disease, Parkinson Disease
Young Onset Parkinson's Disease Subtypes and Pathogenic Mechanisms
Young Onset Parkinson's disease (YOPD) refers to a group of patients in which the disease starts earlier in life (before the age of 50 years) and has a profound impact on most of patient's life.
- Trial name
- YOPD (NCT07752355)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Diabetes
Effect of 2-Week Continuous Glucose Monitoring on Glycemic Management in Patients New-to-Insulin on Hospital Discharge
The proposed study will be a randomized, prospective, non-blinded study of 120 participants with type 1 or type 2 diabetes that are new-to-insulin on hospital discharge.
- Trial name
- NCT05548205
- Testing
- Continuous Glucose Monitor, Blood Glucose Monitor
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Opioid Use Disorder
Assessing Optimal XRB Initiation Points in Jail
This application describes a 3-year, randomized controlled trial. Eligible, consenting adults (N=200) with existing sublingual buprenorphine (SLB) prescriptions who enter Middlesex County House of Corrections (MCHOC) as pre-trial…
- Trial name
- NCT06051890
- Testing
- Extended-Release Buprenorphine (XRB), Sublingual Buprenorphine (SLB)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Iliotibial Band Syndrome
Exercise Program for ITB Syndrome
Patients with diagnosed iliotibial band (ITB) syndrome indicated for non-operative management will be randomized to individualized exercise program or standard physical therapy over the course of 3 months to determine any…
- Trial name
- NCT06269757
- Testing
- Individualized Exercise Program, Standard Physical Therapy
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Prospective Database of Clinical Outcomes Following Cryotherapy for Ablation of Clinically Localized Prostate Cancer
This will be a prospectively maintained research database. The purpose is to record baseline parameters and treatment outcomes following of Cryotherapy for ablation of clinically localized prostate cancer.
- Trial name
- NCT07184957
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- NYU Langone Health
Psoriasis (PsO), Psoriatic Arthritis (PsA)
A Clinical Trial of Antiplatelets in Psoriasis
The purpose of this study is to determine the effect of antiplatelet therapy on the endovascular phenotype in psoriasis, specifically whether clopidogrel reduces vascular endothelial pro-atherosclerotic transcript expression more…
- Trial name
- NCT07744191
- Testing
- Aspirin, Clopidogrel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Skilled Nursing Facility Patients
AI SNF Discharge Quality Improvement Project
This study evaluates an AI-supported workflow tool designed to improve discharge planning for hospitalized medicine patients discharged to skilled nursing facilities (SNFs).
- Trial name
- AI SNF (NCT07746648)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Hospital Inpatients
Behavioral Emergency Response Team (BERT) QI Project
The BERT project will implement a clinical decision support tool that predicts which admitted patients are at higher risk of requiring a Behavioral Emergency Response Team (BERT) intervention within the next 48 hours.
- Trial name
- BERT (NCT07746661)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Central Line-associated Bloodstream Infection (CLABSI)
Central Line-Associated Bloodstream Infection QI Project
This study evaluates a daily electronic health record (EHR) alert designed to reduce unnecessary central venous catheter (CVC) use among hospitalized adults.
- Trial name
- CLABSI (NCT07746674)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Chronic Kidney Disease (Stages 4 and 5)
Kidney RISE: Randomized Integrated Supportive CarE Trial
The purpose of study is to investigate whether adding palliative care to usual chronic kidney disease (CKD) care improves symptoms and quality of life for people with CKD.
- Trial name
- NCT07741357
- Testing
- Kidney RISE
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- NYU Langone Health
Stakeholder Engagement
Enhancing Engagement of Partners in Research
The purpose of this study is to examine the implementation and effectiveness of a bundle of engagement strategies for pediatric patient centered outcomes research (PCOR) studies.
- Trial name
- NCT07166913
- Testing
- Toolkit
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Urinary Dysfunction, Sexual Dysfunction
Sexual and Urinary Function Improvement for Cancer Survivors
The purpose of this study is to test the efficacy of SUFICS-PACT to identify and treat sexual and urinary dysfunction in prostate cancer survivors at NYC H+ H/Bellevue, the oldest public hospital in the US.
- Trial name
- NCT06637852
- Testing
- SUFICS-PACT
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Clinical Outcomes in Prostate Cancer Patients Undergoing HIFU Ablation
Many reports of clinical outcomes following treatment of localized prostate cancer suffer from lack of prospective long-term data using objective and validated outcome instruments.
- Trial name
- NCT07203482
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- NYU Langone Health
Blood Pressure
Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents
Fine particulate matter <2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD).
- Trial name
- AirPressureNYC (NCT05874479)
- Testing
- Active PAC
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- NYU Langone Health
ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft
Cryoneurolysis in Anterior Cruciate Ligament Reconstruction (ACLR)
The purpose of this research study is to assess whether cryoneurolysis will help control pain after ACLR surgery and decrease the need of opioid medications.
- Trial name
- NCT07731178
- Testing
- Pacira Iovera Cryoneurolysis device
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Dry Eye Disease (DED)
TRYPTYR as a Treatment for Patients With Dry Eye Disease (DED)
The purpose of this research study is to determine the effectiveness of TRYPTYR as a treatment for Dry Eye Disease. The primary efficacy variable is change from baseline in the Ocular Surface Disease Index (OSDI) at week 2.
- Trial name
- NCT07732010
- Testing
- TRYPTYR (Acoltremon ophthalmic solution 0.003%)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Cardiovascular Health
Community Engagement for Cardiovascular Health Promotion in Mothers (MomHeartHealth2.0)
This project will test the feasibility, acceptability, and preliminary effects of a tailored cardiovascular (CV) health promotion program, Mom♥Health2.0, leveraging childcare centers as platforms for maternal engagement.
- Trial name
- NCT07724821
- Testing
- Mom♥Health2.0
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Early-stage Breast Cancer, Invasive Ductal Carcinoma of Female Breast
Radiation After No Axillary Nodal Sampling
This is a single arm, pilot, prospective study to evaluate the safety of partial breast irradiation in women who undergo breast conserving surgery without sentinel lymph node biopsy (SLNB) or axillary lymph node dissection…
- Trial name
- RADIANS (NCT07723209)
- Testing
- Partial Breast Irradiation (PBI)
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- NYU Langone Health