Clinical trials: sponsored by NYU Langone Health
COVID-19
COVID-19 PrEP HCW HCQ Study
Off label study to evaluate the efficacy of HCQ for pre-exposure prophylaxis (PrEP) to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
- Trial name
- NCT04354870
- Testing
- Hydroxychloroquine (HCQ)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- NYU Langone Health
Obesity
Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery
This is a randomized, double-blinded, placebo-controlled trial of liraglutide versus placebo over a follow-up period of 12 months in patients at least 18 months following Roux-en-Y gastric bypass (RYGB) who are experiencing…
- Trial name
- NCT03048578
- Testing
- Saxenda
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- NYU Langone Health
All
Patient Satisfaction in the Orthopedic Surgery Clinic
Patients in the orthopedic surgery clinic routinely fill out a patient- reported outcome measurement survey prior to their visit.
- Trial name
- NCT04343027
- Testing
- Review
- Sponsor
- NYU Langone Health
Psychosis, Schizophrenia
Levetiracetam in Early Psychosis
In order to establish target engagement and identify an effective dose the investigators will conduct a placebo-controlled single-dose parallel group trial of levetiracetam 185 mg and 500 mg in 24 medication-naïve early psychosis…
- Conditions
- Psychosis, Schizophrenia, Schizo Affective Disorder, Schizophreniform
- Trial name
- NCT03129360
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Atrophy
Quantifying Quadriceps Atrophy Following Tibial Plateau Fracture
This study will quantify and examine the extent to which the quadriceps femoris muscle group atrophies following tibial plateau fractures and the length of time that atrophy affects function.
- Trial name
- NCT02781623
- Testing
- MRI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- NYU Langone Health
Epidural/Anesthesia
Gravity Flow Technique to Validate Proper Location of Epidural Needle Tip on Obese Parturients
Pregnant women, with a Body Mass Index (BMI) greater than 30 kg/m2, who receive epidural analgesia/anesthesia for childbirth will have epidural catheter placement per our standard procedure, which includes using the gravity flow…
- Trial name
- NCT03437889
- Testing
- Cold Stimulus (Ice)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Alcohol Dependence
A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence
Several lines of evidence suggest that classic hallucinogens such as psilocybin can facilitate behavior change in addictions such as alcohol dependence.
- Trial name
- NCT02061293
- Testing
- Psilocybin, Diphenhydramine, Motivational Enhancement and Taking Action (META)
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis, Covid19
Estimating Prevalence of COVID-19 Infection and SARS-CoV-2 Antibodies in MS Patients
This non-interventional, biospecimen collection study is designed to help us better understand whether MS patients have impaired immune defenses to COVID-19 infection.
- Trial name
- NCT04682548
- Where
- United States
- Volunteers
- 920 people
- Sponsor
- NYU Langone Health
Premature Birth
Parenteral Nutrition Light Protection and Premature Outcomes
Investigators propose a prospective study to investigate the effect of full light protection of the PN on cholestasis and other oxidative stress associated diseases in premature infants when they receive PN for more than one…
- Trial name
- NCT04525872
- Testing
- Full parenteral nutrition light protection of the bag, tubing and lipids
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Stroke
Adherence in Upper Extremity Home-based Rehabilitation
The objective of the proposal is to determine the feasibility of implementing Ecological Momentary Assessment (EMA) and Motivational Interviewing (MI) methods to enhance adherence for a 4-week self-initiated arm training…
- Trial name
- NCT05032638
- Testing
- Therapist guided training, Upper extremity (UE) Training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Heart Failure, Heart Failure With Reduced Ejection Fraction
Building Electronic Tools To Enhance and Reinforce Cardiovascular Recommendations - Heart Failure
This is a feasibility study using a cross-over design to implement and compare a best practice alert (BPA) with an automated in-basket message to inform providers when a patient with heart failure and reduced ejection fraction…
- Trial name
- BETTER CARE-HF (NCT05077293)
- Testing
- Best Practice Alert (BPA), In-Basket Message
- Where
- United States
- Volunteers
- 596 people
- Sponsor
- NYU Langone Health
Medication Errors, Medication Adherence
Improving Communication of Medication Instructions to Parents
Almost half of all US adults have trouble understanding and using health information, or low health literacy. Health literacy is considered to be an important patient safety issue, and has been linked to poor medication…
- Trial name
- NCT01834924
- Testing
- HELPix
- Where
- 2 sites in United States
- Volunteers
- 1,196 people
- Sponsor
- NYU Langone Health
Prostate Cancer, Prostate Cancer Recurrent
Metformin Prostate Cancer Adjuvant Trial
This is a Phase II clinical study to determine if Metformin can increase Prostate Specific Antigen (PSA) doubling time for patients with Prostate Cancer who have failed primary treatment with radiation, or surgical patients that…
- Trial name
- NCT02176161
- Testing
- Metformin Hydrochloride Extended Release 750mg
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- NYU Langone Health
Patient Satisfaction
Increasing Patient Experience Survey Responses
This project aims to evaluate the effect of thank you cards on patient experience survey response rate.
- Trial name
- NCT04994366
- Testing
- Thank you card
- Where
- United States
- Volunteers
- 929 people
- Sponsor
- NYU Langone Health
Patient-reported Outcomes
Using RCT to Increase Completion Rates of the Health Assessment Questionnaire.
The proposed study aims to examine several iterations of instructions/reminders that patients receive for completing the Health Assessment Questionnaire (self-reported health outcomes) for their outpatient visit at NYU Langone…
- Trial name
- NCT03435484
- Testing
- Arm A, Arm B
- Where
- United States
- Volunteers
- 27,263 people
- Sponsor
- NYU Langone Health
Tinnitus
High Dose Oxytocin Nasal Spray for Treatment of Tinnitus
The purpose of this study is to evaluate the effects of high-dose intranasal oxytocin for treating tinnitus. The hypothesis is that high dose intranasal oxytocin can significantly reduce tinnitus severity and disability.
- Trial name
- NCT04210310
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Tibial Tubercle Osteotomy
Reducing Hemarthrosis in Tibial Tubercle Osteotomy by the Administration of Intravenous Tranexamic Acid
The purpose of the proposed study is to evaluate the effects of administering intravenous tranexamic acid (TXA) to patients undergoing high tibial osteotomy (HTO) and tibial tubercle osteotomy (TTO) to minimize hemarthrosis…
- Trial name
- NCT03606109
- Testing
- Tranexamic Acid (TXA)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- NYU Langone Health
Schizophrenia, Bipolar Disorder
The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders
This is a single center study that uses both between-group comparisons and correlational analyses to establish biomarkers of dysmyelination and cognitive impairment in Psychotic Spectrum Disorders using imaging and…
- Trial name
- NCT03166098
- Testing
- Cognitive Function Assessments
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- NYU Langone Health
Cubital Tunnel Syndrome
Effectiveness of Nerve Glide Exercises on Cubital Tunnel Syndrome
The objective of this study is to determine if nerve glide exercises in patients with cubital tunnel syndrome can improve pain, paraesthesias and reduce the need for future surgery.
- Trial name
- NCT03629470
- Testing
- Standard Conservative Treatment, Nerve Gliding Exercises
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- NYU Langone Health
Primary Hyperoxaluria, Cystinuria
Health-related Quality of Life in Rare Kidney Stone
Assessment of Health-related Quality of Life in Rare Kidney Stone Formers in the Rare Kidney Stone Consortium
- Conditions
- Primary Hyperoxaluria, Cystinuria, Adenine Phosphoribosyl Transferase Deficiency, Dent Disease
- Trial name
- NCT02124395
- Testing
- Health-related Quality of Life in Rare Kidney Stone Questionnaire
- Where
- 3 sites in United States, Iceland
- Volunteers
- 365 people
- Sponsor
- NYU Langone Health
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