Clinical trials: sponsored by NYU Langone Health
Dysautonomia, Familial, Baroreflex Failure Syndrome
Carbidopa for the Treatment of Excessive Blood Pressure Variability
The overall study objectives are to determine whether carbidopa (Lodosyn®) is safe and well tolerated and to assess whether it can inhibit catecholamine-induced paroxysmal hypertension and normalize or reduce the exaggerated…
- Trial name
- CarbiFD (NCT02553265)
- Testing
- Carbidopa Low-Dose, Carbidopa High-Dose
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Chronic Disease
Evaluation of Patient Education Simulations to Promote Health and Wellness
This pilot study will use a pre-post design to explore the utility of using virtual simulations to provide participant education and counseling for adopting healthy lifestyle behaviors (i.e., physical activity, nutrition…
- Trial name
- NCT04352179
- Testing
- Virtual Education Simulation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- NYU Langone Health
Recruitment
Advancing People of Color in Clinical Trials Now: Involvement in Trials Using a Patient-Centered Website: A Community-Engaged Approach
The purpose pf this study is to evaluate the comparative effectiveness of a culturally and linguistically tailored clinical trial literacy website in increasing likelihood of participating in clinical trials.
- Trial name
- ACT Now (NCT03243071)
- Testing
- Tailored Website, Standard Website
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Shoulder Pain
Liposomal Bupivacaine (Exparel ® ) Plus 0.5% Bupivacaine HCL Versus 0.5% Bupivacaine HCL for Interscalene Nerve Block (ISB) for Patients Undergoing Total Shoulder Arthroplasty(TSA)
This is a phase IV , randomized, single-blind, single-center study comparing patient related outcomes such as postoperative pain and opioid usage for patients who receive ISB 's containing liposomal bupivacaine (Exparel®) plus…
- Trial name
- NCT03913091
- Testing
- Liposomal Bupivacaine, 0.5% Bupivacaine HCL
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Femoroacetabular Impingement
Patient Satisfaction With Virtual Post Operative Visits: Hip Arthroscopy
This is a prospective, randomized study designed to evaluate the effects of different initial postoperative follow-up modalities.
- Trial name
- NCT04302077
- Testing
- virtual doctor visit, Standard care doctor's visit
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- NYU Langone Health
Ankle Fractures, Tibia Fracture
CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF
The purpose of this study is to evaluate the effects of administering CBD to control post-operative pain in patients undergoing ankle fracture open reduction and internal fixation, tibial plafond (pilon) open reduction and…
- Trial name
- NCT04768478
- Testing
- CBD
- Where
- United States
- Sponsor
- NYU Langone Health
Nephrolithiasis
Effect of Hydroxycitrate on Urine Chemistry
Hydroxycitrate (HCA) is a compound extracted from the fruit, Garcinia Cambogia. Hydroxycitrate supplements are available over the counter and are primarily promoted as a weight loss supplement.
- Trial name
- NCT03348228
- Testing
- Hydroxycitrate (HCA)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Chronic Obstructive Pulmonary Disease, Lower Respiratory Disease
Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust
Many "Survivors" in the World Trade Center (WTC) clinical program have a clinical syndrome characterized by chronic obstruction in small airways and persistence of lower respiratory symptoms despite therapy.
- Trial name
- NCT03089515
- Testing
- Cardio-Pulmonary Exercise Testing (CPET)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Appendicitis
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
Several prior studies have demonstrated that medical management of acute appendicitis in adults is a safe first-line therapy option.
- Trial name
- NCT02991937
- Testing
- Piperacillin/Tazobactam, Surgical Treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Herpes Simplex Virus Keratitis
Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis
This is a prospective, randomized clinical trial looking to determine the role of prophylactic treatment with topical corticosteroids in preventing recurrences in patients with a history of infectious epithelial keratitis…
- Trial name
- NCT03626376
- Testing
- oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily, oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily + topical corticosteroid eye drops
- Where
- United States
- Sponsor
- NYU Langone Health
Covid19
BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)
This multi-center, double-blind, placebo-controlled, randomized Phase 2 trial will study the safety, tolerability, and efficacy of bardoxolone methyl in patients hospitalized with confirmed COVID-19.
- Trial name
- NCT04494646
- Testing
- Bardoxolone Methyl
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Diarrhea
C. Difficile and Ursodiol
In vitro findings have established that ursodeoxycholic acid is a surrogate for deoxycholic acid in preventing the growth of C. difficile, and interrupting recurrence.
- Trial name
- NCT02748616
- Testing
- Ursodiol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- NYU Langone Health
Alzheimer's Disease, Dementia
Tools for Distance Delivery of an Evidence-based AD Family Caregiver Intervention
A 20+ year randomized controlled trial (RCT) demonstrated the many benefits of a counseling and support intervention for spouse caregivers, the NYU Caregiver Intervention (NYUCI).
- Trial name
- NCT02347202
- Testing
- Online counseling via Zoom teleconferencing, Telephone support as needed
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Opioid Dependence
XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept
This is a pilot proof-of-concept randomized controlled trial, open-label and unblinded, examining the feasibility and acceptability of Buprenorphine extended-release vs.
- Trial name
- NCT03604159
- Testing
- Buprenorphine Extended Release, Sublingual Buprenorphine (SUBOXONE, Zubsolv, or generic tablets)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Malaria
Effectiveness of Malaria Camps as Part of the Odisha State Malaria Elimination Drive
The Odisha State Malaria Control Program (India) has introduced 'malaria camps' where teams of health workers visit villages to educate the population, enhance vector control with long-lasting insecticide nets (LLINs) and indoor…
- Trial name
- CSCMi20 (NCT03963869)
- Testing
- Malaria Camps
- Where
- India
- Volunteers
- 2,463 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Smoking Cessation
Integrating the Quit and Stay Quit Monday Model Into Smoking Cessation Services for Smokers With Mental Health Conditions
The Quit and Stay Quit Monday model is an innovative smoking cessation approach that guides smokers' behavior without requiring additional resources.
- Trial name
- NCT04512248
- Testing
- Quit and Stay Quit Monday Model
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Glaucoma
NIDEK Gonioscope GS-1 for Glaucoma
The Gonioscope GS-1 is an ophthalmic camera with gonioscopic prism that is intended to capture, display and store images of the anterior chamber angle and its peripheral part.
- Trial name
- NCT03715231
- Testing
- NIDEK Gonioscope GS-1, Standard Digital Gonioscopic Images
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Pain, Postoperative, Cardiac Surgery
Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery
The primary objective of this study is to determine if the addition of PECS2 block provides superior post-operative analgesia for cardiac surgery patients after midline sternotomy compared to only standard-of-care post-operative…
- Trial name
- NCT04282239
- Testing
- PECS2 block, Ropivacaine 0.5% Injectable Solution, Lidocaine Epinephrine
- Where
- United States
- Sponsor
- NYU Langone Health
Cystinuria
Effect of Increasing Doses of Tiopronin on Cystine Capacity in Patients With Cystinuria
The purpose of this study is to determine the minimum effective dose of the cysteine binding thiol drug (CBTD) Tiopronin on urine cystine capacity, which is a measure of cystine solubility in the urine, in patients with…
- Trial name
- NCT03663855
- Testing
- Tiopronin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis
tDCS for the Management of Multiple Sclerosis Related Fatigue
This is a pragmatic clinical trial that aims to determine the effect of tDCS on symptomatic fatigue in Multiple Sclerosis (MS) patients.
- Trial name
- NCT03838770
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- NYU Langone Health
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