Clinical trials: sponsored by NYU Langone Health
Cardiovascular Disease
PREDHICT: Precision Recruitment and Engagement of Diabetics and Hypertensives in Clinical Studies
For the sub-study, this digital navigation tool will both inform/educate, engage, support, and navigate participants and providers through the process of clinical trial participation via personalization (data profiling, adaptive…
- Trial name
- NCT04286113
- Testing
- control group, Lifestyle management
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cardiovascular Diseases
Providing Personalized Health and Individual Lifestyle Enhancing Solutions (Prophiles) in CVD
The objective of the proposed project is to evaluate the usability, acceptability, and adherence of a lifestyle and behavioral self-tracking and ePersuasive tool aimed at improving: 1) adherence to diet/nutrition (<1500 mg of…
- Trial name
- NCT03643146
- Testing
- Lifestyle Management, Control Group
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Poisoning
Understanding How Medication is Stored in the Home
The goal of this study is to increase safe medication storage practices in homes with young children in order to prevent unintentional childhood poisonings.
- Trial name
- NCT03894306
- Testing
- Medication lock box, medication lock bag, brief counseling
- Sponsor
- NYU Langone Health
Mental Health
Implementing a Digital Child Mental Health Screening, Literacy, and Management Tool in Faith-Based Settings
The proposed project is to develop a Pediatric-Mental Health Digital Toolkit (P-MHDT) Toolkit to support innovative child mental health preventive interventions in FBO settings.
- Trial name
- NCT03651050
- Testing
- Faith Based Outreach (FBO), community-health-workers (CHW)
- Where
- United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Multiple System Atrophy
A Futility Trial of Sirolimus in Multiple System Atrophy
Single-center, randomized, placebo-controlled, phase-II, futility clinical trial to determine if oral sirolimus is of sufficient promise to slow disease progression in MSA, prior to embarking on a large-scale and costly phase III…
- Trial name
- NCT03589976
- Testing
- Sirolimus 2 MG
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- NYU Langone Health
Lung Injury, Particulate Matter Inhalation Injury
Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial
This is a randomized-controlled unblinded clinical trial to investigate dietary intervention on metabolic biomarker assessment in World Trade Center (WTC) Lung Injury (LI) in firefighters.
- Trial name
- NCT03581006
- Testing
- Low-Calorie Mediterranean Diet, Technology based monitoring and behavioral participation, Usual care group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Oral Cancer
Oral Pathology Asynchronous Telementoring Pilot Study
The purpose of the proposed research project is to evaluate and enhance the feasibility and acceptability of integrating a tele-mentoring component into the identification of oral lesions at the 6 dental clinics of Family Health…
- Trial name
- NCT04166214
- Testing
- Imaging using intraoral cameras
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Chronic Kidney Diseases, Hyperkalemia
Use of Patiromer to Transition Chronic Kidney Disease Patients With Hyperkalemia to a Plant-rich Diet.
The purpose of this proof-of-concept controlled-feeding study is to determine whether patiromer (Veltassa®, Relypsa, Inc., Redwood City, CA) can be used to maintain normal serum potassium concentrations in chronic kidney disease…
- Trial name
- NCT03183778
- Testing
- Patiromer, Research Diet Menu
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- NYU Langone Health
Neurofibromatosis Type 2, Vestibular Schwannomas
Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
The purpose of this study is to determine if the study drug, AXITINIB, has any effect on tumors found in patients with Neurofibromatosis Type 2 (NF2).
- Trial name
- NCT02129647
- Testing
- Axitinib
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- NYU Langone Health
Rhinoplasty, Non-steroidal Ant Inflammatory Drugs
Narcotics vs NSAIDs for Post-operative Analgesia in Outpatient Rhinoplasty
The purpose of this study is to compare the efficacy and safety of oral opiate pain medication vs non-steroidal ant inflammatory drugs (NSAIDs) in the treatment of postoperative rhinoplasty pain.
- Conditions
- Rhinoplasty, Non-steroidal Ant Inflammatory Drugs, Opioid Use
- Trial name
- NCT03457116
- Testing
- Norco, NSAID
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- NYU Langone Health
Breast Cancer, Metastatic Breast Cancer
Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases
This study is to find an optimal dose of Imiquimod (IMQ) in the first part (Phase I) and test the effectiveness of the combination treatment of IMQ, cyclophosphamide (CTX), and radiotherapy (RT) in patients with skin metastases…
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Recurrent Breast Cancer
- Trial name
- NCT01421017
- Testing
- Radiation, Imiquimod, Cyclophosphamide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Small Cell Lung Cancer (SCLC)
Study of Pembrolizumab and Chemotherapy With or Without Radiation in Small Cell Lung Cancer (SCLC)
This trial is to assess the efficacy of pembrolizumab added to concurrent chemotherapy with or without radiation therapy in patients with small cell lung cancer (SCLC).
- Trial name
- NCT02934503
- Testing
- Pembrolizumab, Cisplatin, Carboplatin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- NYU Langone Health
Vitiligo
Stress Response Pathways in Vitiligo
The purpose of this study is to investigate stress response pathways in tissues and melanocytes from patients with vitiligo. Investigators are collecting evidence of UPR and stress response activation in tissues and melanocytes…
- Trial name
- NCT02797574
- Testing
- Punch Biopsy at a Lesional Site, Punch Biopsy at a Non- Lesional site
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Diabetes
BRInging the Diabetes Prevention Program to GEriatric Populations - PILOT
The purpose of this pilot study is to test the feasibility of implementing a telehealth adaption of the Diabetes Prevention Program (DPP) intervention among 30 NYC senior center members.
- Trial name
- BRIDGE (NCT03524404)
- Testing
- 6 Week Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder
Shire SCT: Lisdexamfetamine Treatment for ADHD and SCT
The primary purpose of this study is to test the efficacy of Lisdexamfetamine in Adults With Attention Deficit Hyperactivity Disorder (ADHD) and Sluggish Cognitive Tempo (SCT).
- Trial name
- NCT02635035
- Testing
- Lisdexamfetamine
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- NYU Langone Health
Smoking, Smoking Cessation
Preventing Smoking Relapse After Total Joint Replacement Surgery
Hospitalization for elective knee or hip replacement surgery presents an outstanding opportunity to motivate people to quit smoking, because it provides an opportunity to encourage patients to remain smoke-free as they…
- Trial name
- NCT03673228
- Testing
- Comprehensive Relapse Prevention Intervention, Standard Treatment Counseling, Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis
Ticagrelor in Methotrexate-Resistant Rheumatoid Arthritis
This is an open label study to assess the improvement in the Disease Activity Score for 28-joint counts (DAS28) with ticagrelor given at 90 mg twice daily in patients with RA who have active disease despite MTX therapy (as…
- Trial name
- TIMERA (NCT02874092)
- Testing
- Ticagrelor, MTX therapy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
New Biomarkers for Measuring Vitamin D Level
A New Paradigm for Vitamin D Sufficiency
Although the African-American (AA) population tends to have lower serum 25(OH)D levels compared to whites, there is no evidence that the lower 25(OH)D levels in African-Americans are harmful.
- Trial name
- NCT02969850
- Testing
- Vitamin D Supplementation, Calcium
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Physician-Patient Relations, Nurse-Patient Relations
Adapt and Incorporate dDPP Into Clinical Workflows
This observational study will seek to adapt a digital diabetes prevention program (dDPP) tool suite into clinical workflows. This tool pushes key dDPP data elements (e.g.
- Trial name
- NCT04049500
- Testing
- Digital Diabetes Prevention Program (dDPP)
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pancreatic Cancer
Study of Nivolumab, Cabiralizumab, and Stereotactic Body Radiotherapy (SBRT) for Locally Advanced Unresectable Pancreatic Cancer
A multi-institutional, single arm phase II study of nivolumab, cabiralizumab and stereotactic body radiotherapy (SBRT) in patients with LAUPC.
- Trial name
- NCT03599362
- Testing
- Nivolumab + Cabiralizumab, Stereotactic Body Radiotherapy (SBRT)
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- NYU Langone Health
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