Clinical trials: sponsored by NYU Langone Health
Post-traumatic Stress Disorder
Feasibility Open Label Study Evaluating The Use Of Process-Instructed Self Neuro-Modulation (PRISM) For Post-Traumatic Stress Disorder
This is a single-arm, open-label feasibility study. A maximum of 15 participants will be enrolled. All participants will undergo a novel neurofeedback intervention, targeting down-regulation of deep limbic structures…
- Trial name
- PRISM (NCT04496557)
- Testing
- PROCESS-INSTRUCTED SELF NEURO-MODULATION (PRISM)
- Where
- United States
- Sponsor
- NYU Langone Health
Diabetes
Diabetes Prevention for Black Men
Geographic analyses of diabetes burden have found that poor glycemic control, high rates of diabetes-related hospital utilization, and a high prevalence of microvascular diabetic complications all cluster in the same…
- Trial name
- NCT03708380
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
COVID-19
Gargling and Nasal Rinses to Reduce Oro- and Nasopharyngeal Viral Load in Patients With COVID-19
For this study, 48 patients who have been diagnosed with COVID-19 will be randomly assigned to four study groups: control, saline, chlorhexidine gluconate, and povidone-iodine.
- Trial name
- NCT04344236
- Testing
- Saline oral/nasal rinse, 0.5% Povidone/Iodine oral/nasal rinse, 0.12% Chlorhexidine oral/nasal rinse
- Where
- United States
- Sponsor
- NYU Langone Health
Old Age; Debility
Safety and Feasibility of a Novel In--Bed Resistance Training Device in Elderly Inpatients
The purpose of this study is to decrease deconditioning of elderly inpatients in acute care institutions and to assess the safety and feasibility of a newly developed resistance training device.
- Trial name
- NCT04026802
- Testing
- In-Bed Resistance Training Device, Standard of Care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- NYU Langone Health
Prostate Cancer
Axumin PETMRI Imaging Following Focal Cryo-ablation (FCA)
This is a prospective outcomes study assessing quality of life and oncological control at pre-defined time points following FOCAL CRYO-ABLATION (FCA).
- Trial name
- NCT04009083
- Testing
- Standard of Care MRI, Fluciclovine PET scan added to MRI
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Traumatic Brain Injury, Vascular Accident, Brain
Speed of Processing Training in Traumatic Brain Injury
The purpose of this project is to test the hypothesis that Speed of Information Processing (SIP) deficits in acquired brain injury (ABI) can be remediated.
- Trial name
- NCT02507271
- Testing
- Brain Fitness Program, Weekly Telephone Contact
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
End Stage Renal Disease
The Effect of an Antibiotic on the Production of Uremic Toxins by the Gut Microbiome
The purpose of this study is to determine if multiple doses of vancomycin over the course of 3 months will perturb the intestinal flora (microbiome) and result in reduced serum concentration of the uremic toxin indoxyl sulfate…
- Trial name
- NCT03452189
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis, Cognition Disorders
Linking Cognitive Functioning to Multimodal Imaging in Multiple Sclerosis (MS)
Multiple sclerosis (MS) is the most common progressive neurologic disorder to occur in adults of working-age. Despite longstanding recognition of cognitive impairment as a symptom of MS, two obstacles in measurement have limited…
- Trial name
- NCT03723356
- Testing
- Siemens Biograph mMR (molecular MR), fMRI, Diffusion Spectrum Imaging (DSI)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Arthritis, Glenohumeral Osteoarthritis
3D MR Versus 3D CT for Glenohumeral Arthritis
This study aims to assess the efficacy of three-dimensional magnetic resonance (MR) compared to three-dimensional computed tomography (CT) imaging.
- Trial name
- NCT03379545
- Testing
- 3-dimensional (3D) magnetic resonance (MR) imaging, 3D computed tomography (CT) imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Gaucher Disease
Genzyme Osteopenia/Osteoporosis Study
Gaucher disease is a most common genetic metabolic disease characterized by low platelet number, liver and spleen enlargement and various forms of bone diseases including low bone mineral density leading to brittle bones.
- Trial name
- NCT02785744
- Testing
- Gaucher disease DNA mutation analysis
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- NYU Langone Health
Neurofibromatosis 1 and 2 (NF1 and NF2)
A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)
Patients with clinically confirmed neurofibromatosis type 1 (NF1) or neurofibromatosis type 2 (NF2) or a known neurofibromatosis (NF) mutation aged 5 years and above will be eligible to participate and will be recruited from the…
- Trial name
- NCT03672838
- Testing
- hand-held dynamometer
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Mental Health Issue
Improving Physical, Mental, and Spiritual Health in Faith-Based Settings Through Creating a Healthy Culture in Bronx, NY
The proposed study "Improving Physical, Mental, and Spiritual Health in Faith- Based Settings through Creating a Healthy Culture in Bronx, NY" aims to assess the efficacy of a holistic health intervention that seeks to integrate…
- Trial name
- NCT04353427
- Testing
- The Seven Pathways to Healing, Health and Wellness curriculum
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Discoid Lupus Erythematosus
Safety Study of Clinical and Immune Effects of Phosphodiesterase 4 (PDE-4) Inhibitor in Cutaneous Lupus Patients
The purpose of this study is to determine the clinical and immunological effects of the phosphodiesterase type 4 inhibitor, CC-10004, on skin inflammation associated with cutaneous lupus erythematosus.
- Trial name
- NCT00708916
- Testing
- CC-10004
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NYU Langone Health
Congenital Heart Block, Neonatal Lupus
Preventive Approach to Congenital Heart Block With Hydroxychloroquine
Women with antibodies to proteins called SSA/Ro and or SSB/La face a 2% chance of having a child with a life threatening heart condition regardless of whether they have very active lupus, are in remission, or have only vague…
- Conditions
- Congenital Heart Block, Neonatal Lupus, Autoantibody-Associated Heart Block
- Trial name
- PATCH (NCT01379573)
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- NYU Langone Health
Anterior Cruciate Ligament Reconstruction
Reducing Hemarthrosis in ACL Reconstruction With BTB Autograft by the Administration of Intravenous TXA
The purpose of the proposed study is to evaluate the effects of administering intravenous tranexamic acid (TXA) to patients undergoing anterior cruciate ligament (ACL) reconstruction with bone-patellar tendon-bone autograft to…
- Trial name
- NCT03631355
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- NYU Langone Health
Elderly, Alzheimer Disease
Orexin and Tau Pathology in Cognitively Normal Elderly
Alzheimer's disease (AD) is a common neurodegenerative disease characterized by the accumulation of amyloid plaques and neurofibrillary tangles.
- Trial name
- NCT03053908
- Testing
- Actigraphy, Nocturnal Polysomnograpahy (NPSG)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Familial Dysautonomia
The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia
Familial dysautonomia (FD) is a devastating hereditary disease in which the development of selective neuronal populations is impaired because of a deficiency of the protein IKAP (Slaugenhaupt, 2002). There is no known cure.
- Trial name
- NCT02276716
- Testing
- Phosphatidylserine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- NYU Langone Health
Early Stage Breast Cancer
Cyberknife for Early Stage Breast Cancer
This phase II study based on the Cyberknife Society study will evaluate the technical feasibility and acute toxicity of Partial Breast Irradiation (PBI) with the Cyberknife.
- Trial name
- NCT03946683
- Testing
- Cyberknife for Early Stage Breast Cancer
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- NYU Langone Health
Emergencies, Diabetes Mellitus
Geography of ED Use and Population Health
The goal of this study is to create predictive models of emergency care and metrics for population health that can be used to analyze how events like hospital closures or disasters like Hurricane Sandy affect health care…
- Trial name
- NCT03254524
- Testing
- Statewide Planning and Research Cooperative System Database
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alzheimer Disease
Detecting an Early Response to Donepezil With Measures of Visual Attention
Acetylcholinesterase inhibitors (AChE-I) comprise a class of drugs used to treat Alzheimer's disease (AD), but controversy about their usefulness remains.
- Trial name
- NCT03073876
- Testing
- Donepezil Hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
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