Clinical trials: sponsored by NYU Langone Health
Epidural Anesthesia
Gravity Flow Technique to Validate Proper Location of Epidural Needle Tip
Epidural analgesia for childbirth may fail to provide adequate pain relief. At NYULMC, to maximize the likelihood that epidural analgesia will work well, the gravity flow technique is used when performing epidural procedures.
- Trial name
- NCT03317626
- Testing
- Cold Stimulus (ice) Test
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hypertension
Emotional Awareness and SElf-regulation for Depression in Patients With Hypertension (EASE) Study
The purpose of this study is to adapt and then evaluate the feasibility, acceptability, and efficacy of a telephone-based intervention (UPLIFT: Using Practice and Learning to Increase Favorable Thoughts) for individuals with…
- Trial name
- NCT03013907
- Testing
- UPLIFT, Usual care
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- NYU Langone Health
Pregnancy Related, Diet Modification
Effects of Diet on Pregnancy Outcome and Child Obesity
The purpose of the study is to compare 3 different diets in pregnancy, equal in calories, and fats, different in refined grains compared to whole grains as a source of carbohydrates, and in calories from carbohydrate, compared to…
- Conditions
- Pregnancy Related, Diet Modification, Obesity, Hypertension
- Trial name
- NCT03232762
- Testing
- Refined Grains, Whole Grains
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Atrial Fibrillation
The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation
This is a two arm randomized, paired prospective study comparing the percentage of time spent above Contact Force (CF), Force Time Integral (FTI) and other lesion parameters in the setting of pacing versus non-pacing.
- Trial name
- PEP AF (NCT02766712)
- Testing
- Pace During 1st Half of Lesion, Pace During 2nd Half of Lesion
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- NYU Langone Health
Heart Failure
Health Information Technology in Heart Failure Care
The objective of this proposal is to develop, implement, and test the effectiveness of a computerized clinical decision support system for hospitalized patients with heart failure.
- Trial name
- NCT02858674
- Testing
- Pop Up Interruption Alert, Side Bar Non Interruptive Provider Checklist
- Where
- United States
- Volunteers
- 958 people
- Sponsor
- NYU Langone Health
Smoking Cessation, Smoking, Cigarette
Incorporating Financial Incentives to Increase Smoking Cessation Among Asian Americans Residing in New York City
Financial incentives for motivating health change have been increasingly employed in various healthcare sectors. They can be a potentially effective approach to promote smoking behavioral change and increase the use of…
- Trial name
- NCT03397511
- Testing
- Financial Incentives
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Canavan Disease
A Natural History Study of Canavan Disease
The purpose of this study is to learn more about the natural history of Canavan disease
- Trial name
- NCT02851563
- Where
- 3 sites in United States, Germany
- Volunteers
- 21 people
- Sponsor
- NYU Langone Health
ADHD, Attention Deficit Hyperactivity Disorder
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
Organizational, time management and planning (OTMP) skills deficits are seriously impairing features of developmental disorders, such as Attention Deficit Hyperactive Disorder (ADHD) and autism, which compromise school…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders
- Trial name
- NCT03148782
- Testing
- OST Intervention for participants with Organizational skill difficulties
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Congenital Heart Block, Neonatal Lupus
Preventive IVIG Therapy for Congenital Heart Block
Neonatal lupus (NL) is the name given to a group of conditions that can affect the babies of mothers who have certain autoantibodies against components of the body's cells that are called SSA/Ro and SSB/La.
- Conditions
- Congenital Heart Block, Neonatal Lupus, Autoantibody-associated Heart Block
- Trial name
- PITCH (NCT00460928)
- Testing
- intravenous immune globulin (IVIG)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Ovarian Cancer
Pharmacokinetic Study of Avastin and Doxil in Ovarian Cancer
This study is to study pharmacokinetics of Doxil using Doxil and Avastin on ovarian cancer patients who are resistant to or have relapsed from platinum-based therapy.
- Trial name
- NCT00846612
- Testing
- Doxil, Bevacizumab (Avastin)
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Asthma
Sputum-derived Cellular Targets After Xolair (Omalizumab)
The primary purpose of this study is to identify additional mechanisms of action of omalizumab that will lead to improved stratification of patients for treatment.
- Trial name
- NCT02658877
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- NYU Langone Health
Hypertension
Tailored Approaches to Improve Medication Adherence
The purpose of this study is to to culturally tailor a technology-based individualized adherence intervention for Black and Latino patients with uncontrolled HTN or T2DM, who are non-adherent to their medications, and determine…
- Trial name
- NCT01643473
- Testing
- Adherence Intervention, Attention Control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- NYU Langone Health
Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants
Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates
Oral feeding of neonates while on nasal continuous positive airway pressure (NCPAP) is a common practice in many neonatal intensive care units (NICU) all over the country.
- Conditions
- Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants, Respiratory Aspiration, Newborn, Premature
- Trial name
- NCT02661256
- Testing
- NCPAP, Varibar® Thin Liquid Barium Sulfate for Suspension
- Volunteers
- 7 people
- Sponsor
- NYU Langone Health
Breast Cancer, Lymphedema
LLLT Combined With CDT in Breast Cancer-Related Lymphedema
This study aims to explore the effects of Low Level Laser Therapy (LLLT) on breast cancer-related lymphedema when utilized in conjunction with Complex Decongestive Therapy (CDT) when compared to CDT treatment alone.
- Trial name
- NCT01351376
- Testing
- Low Level Laser Therapy, Low Level Laser
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- NYU Langone Health
Diabetes
CSII Pilot in Adolescents With Type 2 Diabetes
This feasibility pilot is intended to understand whether adolescents with Type 2 Diabetes (2DM) can be transitioned to a continuous subcutaneous insulin injection (CSII) and if so, assess whether CSII is a feasible treatment…
- Trial name
- NCT02748122
- Testing
- MMT 723
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Systemic Lupus Erythematosus (SLE), Repository Corticotropin Injection
Acthar SLE (Systemic Lupus Erythematosus)
This is a randomized study exploring the efficacy, safety and steroid sparing ability of two doses (40 U and 80 U) of Acthar in SLE patients with immune mediated hematologic manifestations requiring steroid use for a minimum of 2…
- Trial name
- Acthar SLE (NCT02779153)
- Testing
- Acthar low dose (40 U), Acthar high dose (80 U)
- Sponsor
- NYU Langone Health
MRSA
Use of Disposable Stethoscope Covers for Reduction of Stethoscope MRSA Contamination
This is a prospective pilot study using a randomized, controlled, single blinded, crossover trial design, evaluating the effect of daily antimicrobial stethoscope diaphragm covers versus uncovered stethoscope.
- Trial name
- NCT03601741
- Testing
- Daily Antimicrobial Stethoscope Diaphragm Cover, Uncovered Stethoscopes
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Opioid-use Disorder
Emergency Department Connection to Care With Buprenorphine for Opioid Use Disorder
The purpose of this study is to learn what resources are needed to improve outcomes for patients with opioid use disorder. The study will look at how patients engage in treatment and the decisions that patients and providers make…
- Trial name
- ED-CONNECT (NCT03544112)
- Testing
- Employ a multifaceted approach to facilitate clinical protocol implementation, Initiate BUP (SL-BUP or XR-BUP) in the ED
- Where
- 4 sites in United States
- Volunteers
- 390 people
- Sponsor
- NYU Langone Health
Intracranial Aneurysm, Brain Edema
Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
This is a prospective, randomized controlled trial to determine if using FloTrac/EV1000 system in neurosurgical patients undergoing craniotomies for aneurysm repair or tumor resection complicated by cerebral edema, or complex…
- Conditions
- Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
- Trial name
- NCT02701582
- Testing
- Phenylephrine, Epinephrine, Albumin
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- NYU Langone Health
Schizophrenia, Nicotine Dependence
Music to Reduce Use of Smoking in Patients With Schizophrenia
The purpose of this study is to explore the impact of self-selected music listening which targets disrupting the reward process maintaining smoking and additionally attenuating the reward processing deficits associated with…
- Conditions
- Schizophrenia, Nicotine Dependence, Smoking, Tobacco
- Trial name
- NCT03190161
- Testing
- Music session
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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