Clinical trials: sponsored by Nationwide Children's Hospital
Exposed to Anesthesia
Functional Magnetic Resonance Imaging (fMRI) Findings in Children With Early Exposure to General Anesthesia
General anesthetic medications have been shown to cause neuronal cell death in the brains of infant rodents. Ethanol and general anesthetics both act on NMDA and GABA receptors,and appear to have similar mechanisms of toxicity in…
- Trial name
- NCT01229514
- Testing
- fMRI
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Cardiac Surgery, Spinal Surgery
CNAP™ Monitor Study
A newly developed monitor for continuous non-invasive blood pressure monitoring (CNAP™ Monitor 500; CNSystems Medizintechnik AG, Graz, Austria) provides beat-to-beat BP readings and is non-invasive.
- Trial name
- NCT01356082
- Testing
- CNAP
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Nationwide Children's Hospital
Surgical Patients
Heart Rate Changes With Propofol
This is a prospective pilot study to quantify the changes in heart rate when propofol is administered after inhalational anesthesia induction.
- Trial name
- NCT01355432
- Testing
- Observation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nationwide Children's Hospital
Childhood Obesity
Anticipatory Guidance to Prevent Childhood Obesity
The purpose of this pilot project is to test anticipatory guidance, which is information given to families during a well child visit to prevent obesity during childhood.
- Trial name
- MOMS (NCT01565525)
- Testing
- Maternal focused intervention, Ounce of Prevention
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Duchenne Muscular Dystrophy
Six Month Study of Gentamicin in Duchenne Muscular Dystrophy With Stop Codons
The purpose of this study is to determine the safety of giving intravenous (IV) gentamicin to boys with Duchenne muscular dystrophy who have stop codon mutations.
- Trial name
- NCT00451074
- Testing
- Gentamicin infusions twice a week for six months
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
Postoperative Pain Management
Review of Pain Management After Congenital Cardiac Surgery
One of the main problems that faces children undergoing congenital cardiac surgery is posoperative pain management. PCAs (Patient Controlled Analgesia) and NCAs (Nurse Controlled Analgesia) are the main means of pain management…
- Trial name
- NCT01378663
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Nationwide Children's Hospital
Other Reconstructive Surgery
Retrospective Femoral Nerve Block Study
This is a retrospective review to evaluate the efficacy of femoral nerve block in providing analgesia following reconstructive surgery of the knee and to compare the postoperative course of patients who received femoral nerve…
- Trial name
- NCT01293136
- Testing
- Femoral nerve block, Intravenous opioids
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Nationwide Children's Hospital
Spinal Fusion
Prevalence of Inadvertent Hyperventilation During Intraoperative Anesthetic Care
This is a retrospective chart review of patients undergoing spinal fusion surgery to see the prevalence of hyperventilation.
- Trial name
- NCT01235650
- Volunteers
- 160 people
- Sponsor
- Nationwide Children's Hospital
Cardiac Surgical Procedures
Masimo CO-Oximeter Study
This is a study to evaluate the accuracy of the Masimo Rainbow SET Pulse CO-Oximeter in monitoring the hemoglobin levels of patients undergoing isovolemic hemodilution.
- Trial name
- NCT01184521
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nationwide Children's Hospital
Adenoidectomy, Tonsillectomy
Impact of Using a Cuffed Endotracheal Tube on Limiting the Risk of Airway Fire
The purpose of this study is to evaluate the impact of using a cuffed endotracheal tube (ETT) on the oxygen concentration in the oropharynx during adenoidectomy, tonsillectomy, or adenotonsillectomy.
- Conditions
- Adenoidectomy, Tonsillectomy, Adenotonsillectomy
- Trial name
- NCT01285804
- Testing
- Cuffed ETT, Uncuffed ETT
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Nationwide Children's Hospital
Interactive Voice Response (IVR)
Treatment Follow-up Study
This study will assess the effectiveness of a medication safety monitoring method utilizing interactive voice response technology for youth recently prescribed anti-depressant medication.
- Trial name
- PhaST (NCT00995696)
- Testing
- PhaST IVR Calls
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Hypertension
Recognition of Abnormal Pediatric Blood Pressures in Primary Care
This study will look at general pediatricians' effectiveness at screening children for elevated blood pressure values in the primary care setting.
- Trial name
- NCT00130663
- Testing
- PDA blood pressure screening program and chart reminder
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Acute Respiratory Distress Syndrome
Short Term Outcomes of Children With Acute Respiratory Distress Syndrome
The study is a chart review of all children admitted over a two year period with the diagnosis of acute respiratory distress syndrome.
- Trial name
- NCT00142376
- Where
- United States
- Sponsor
- Nationwide Children's Hospital