Clinical trials: sponsored by Northwestern University
Hearing Loss, Sensorineural, Cognitive Impairment
Administration Method of Cognitive Screening in Older Individuals With Hearing Loss
The objectives of the current project aim to determine whether a more controlled amplification method or a visual administration has an effect on hearing impaired older individuals' cognitive test scores.
- Trial name
- NCT03402932
- Testing
- Auditory amplified, Visual, Auditory unamplified
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Type 2 Diabetes
Promoting the Universal Medication Schedule Via Mobile and EHR Technologies
The purpose of this study test the effectiveness of the Universal Medication Schedule (UMS), which was designed as a strategy to standardize and simplify medication instructions to support safe and effective prescription drug use…
- Trial name
- NCT02248857
- Testing
- UMS Strategy, SMS Texting Reminders
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Northwestern University
Chronic Kidney Diseases, Chronic Heart Failure
Iron Deficiency and FGF23 Regulation in CKD and HF
This study investigates the effects of intravenous (IV) iron sucrose therapy on blood levels of Fibroblast Growth Factor 23 (FGF23, a protein that regulates the amount of phosphate in the body) in iron deficiency anemia in…
- Conditions
- Chronic Kidney Diseases, Chronic Heart Failure, Iron Deficiency Anemia
- Trial name
- INDIGO (NCT03106298)
- Testing
- Iron Sucrose
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obstructive Sleep Apnea, Insomnia
Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep Apnea
The overall goal of this project is to determine the efficacy of a multidisciplinary treatment model for patients with Obstructive Sleep Apnea (OSA) and comorbid Insomnia.
- Trial name
- MATRICS (NCT01785303)
- Testing
- CBT-I, CPAP
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Northwestern University
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Prostatitis
Chemokine Mechanisms in Chronic Pelvic Pain
The purpose of this study is to identify biomarkers that can be utilized in the diagnosis of chronic pelvic pain syndrome in men.
- Trial name
- NCT01676857
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Stroke, Hemiparesis
Sideways Treadmill Training to Improve Paretic Leg Stepping in Persons Post-Stroke
People who are living in the community following a stroke fall frequently. The ability to take a step in response to a balance disturbance helps to prevent falls but stroke survivors tend not to step with their paretic leg in…
- Trial name
- NCT02516176
- Testing
- treadmill training
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Food Allergy
Introduction and Maintenance of Still Eating Protein Blends in Support of Infant Nutritional Goals
The purpose of the study is to test a food supplement to: Show that the food supplement is well tolerated and safe to feed to infants; Find out how often parents/caregivers feed their infants the food supplement; Find out how…
- Trial name
- NCT03667118
- Testing
- Food Supplement
- Where
- United States
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain Syndrome, Disability Physical
Impact of Combined Psychotherapy and Physiotherapy Group Treatment Program for Survivors of Torture
The aim of this study is to assess the impact and feasibility of an interdisciplinary group treatment approach, involving psychotherapy and physiotherapy, with survivors of torture that are incarcerated in a prison in Kurdistan…
- Trial name
- NCT03470779
- Testing
- Physiotherapy, Psychotherapy
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Sarcopenia
Implementing Resistance Exercise to Reduce Frailty for Older Adult
To develop an intervention specifically targeted for these clients who have the frailty syndrome. The Investigators propose to develop an exercise intervention that can reduce frailty in older adults to facilitate their ability…
- Trial name
- NCT02942992
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Northwestern University
Gastric Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Docetaxel, Oxaliplatin, and Fluorouracil in Treating Patients With Metastatic or Unresectable Stomach Cancer, Gastroesophageal Junction Cancer, or Other Solid Tumor
RATIONALE: Drugs used in chemotherapy, such as docetaxel, oxaliplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00711243
- Testing
- docetaxel, fluorouracil, oxaliplatin
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Northwestern University
Patients, Programming Languages
Designing a Programming Language for Patient-Oriented Prescriptions
The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of improving safety and efficacy of patient care.
- Trial name
- POP-PL (NCT02820168)
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lymphoma
Alemtuzumab in Treating Patients With Relapsed or Refractory Advanced Mycosis Fungoides or Sézary Syndrome
RATIONALE: Monoclonal antibodies such as alemtuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00057967
- Testing
- alemtuzumab
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Northwestern University
Zika Virus Symptoms and the Associated Exanthema
Dermatologic Manifestations of Zika Virus
The purpose of this study is to determine whether any diagnostic patterns exist in the symptom presentation of Zika Virus.
- Trial name
- DMZV (NCT03229421)
- Testing
- Survey
- Where
- Dominican Republic
- Sponsor
- Northwestern University
Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML
The purpose of the study is to determine if metformin in combination with cytarabine is safe and effective. Participants in this research study have acute myeloid leukemia (AML) that has come back after initial treatment or has…
- Conditions
- Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b)
- Trial name
- NCT01849276
- Testing
- metformin hydrochloride, cytarabine, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Northwestern University
Depression
Technology Assisted Programs That Promote Mental Health for Teenagers
The mission of this project is to develop novel systems of care that can provide efficacious, scalable, cost-effective, participant friendly behavioral intervention technologies (BITs) for the prevention of depression in…
- Trial name
- ProjectTECH (NCT01912729)
- Testing
- Networked Peer Support with Peer Guide, Networked Peer Support with Clinician Coach
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lymphoma
Study of Pegylated Interferon-Alfa 2b in Combination With PUVA Therapy In CTCL
RATIONALE: PEG-interferon alfa-2b may interfere with the growth of cancer cells and slow the growth of mycosis fungoides/Sezary syndrome. Ultraviolet light therapy uses a drug, such as psoralen, that is absorbed by cancer cells.
- Trial name
- NCT00724061
- Testing
- Pegylated interferon α-2b, Psoralens with ultraviolet light A, Narrowband-ultraviolet light B
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Northwestern University
Liver Diseases, Hepatocellular Cancer
A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation
Living donor liver transplantation (LDLT), involves complex systems and processes of care that are particularly vulnerable to medical errors and preventable complications.
- Conditions
- Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis
- Trial name
- NCT02073435
- Testing
- Donor pain management
- Where
- 4 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Breast Carcinoma Metastatic in the Bone, Circulating Tumor Cell Count
Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cells
The purpose of this study is to look at the amount of cancer cells in the blood of participants who are being treated with denosumab.
- Conditions
- Breast Carcinoma Metastatic in the Bone, Circulating Tumor Cell Count, Estrogen Receptor Positive, HER2/Neu Negative
- Trial name
- NCT03070002
- Testing
- Denosumab, Laboratory Biomarker Analysis
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Melanoma
Teaching Skin Self-Examination to First-degree Relatives of Melanoma Patients Using Mobile App Technology
The proposed study builds upon the success of our research program (STU00017005: Interventions to teach melanoma patients skin self-examination and the continuation STU0201983) designed to increase early detection of melanomas…
- Trial name
- NCT03177941
- Testing
- Eviderma Smart Phone Teledermatology Application (Eviderma)
- Where
- United States
- Sponsor
- Northwestern University
Pregnancy, Weight Gain
Maternal-Offspring Metabolics:Family Intervention Trial
The prevalence of maternal overweight and obesity has nearly doubled in the United States since 1976. In 2004-2005, 42% of pregnant women had body mass index (BMI) above 25 versus 23% in 1993.
- Trial name
- MOMFIT (NCT01631747)
- Testing
- Lifestyle Intervention Group, Usual Care Group
- Where
- 2 sites in United States
- Volunteers
- 281 people
- Sponsor
- Northwestern University