Clinical trials: sponsored by Odense University Hospital
Myocardial Infarction, Coronary Artery Disease
Coronary Artery Healing and Bioresorbable Scaffold
To compare coronary healing after optical coherence tomography guided versus conventionally angiography guided percutaneous coronary intervention with the Magmaris bioresorbable scaffold.
- Trial name
- HONEST (NCT03016624)
- Testing
- OCT guided PCI, Angiography guided PCI
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Odense University Hospital
Lymphedema
Lymphedema Screening
Breast cancer-related lymphedema is one of the most common and feared consequences of breast cancer treatment. Currently, there is no established screening program for lymphedema.
- Trial name
- LymphScreen (NCT04606511)
- Testing
- Circumference tape measurements, Indocyanine green lymphangiography, bioimpedance spectroscopy
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Odense University Hospital
Colorectal Cancer, Anastomotic Leak
Indocyanine Green Fluorescent Imaging in Robotic Assisted Rectosigmoidal Resection; a Multicenter Assessment of Interobserver Variation and Comparison With Computer-based Pixel Analysis
A serious complication to colorectal surgery is anastomotic leakage (AL). AL increases post-operative mortality, decreases long-term survival, reduces the functional result and reduces qual-ity of life.
- Trial name
- NCT04766060
- Testing
- Fluorescent Imaging
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Odense University Hospital
Post Herpetic Neuralgia, Herpes Zoster
Treatment of Chronic Postherpetic Pain With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post herpetic neuralgia.
- Trial name
- NCT03584061
- Testing
- Fat grafting
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Psoriatic Arthritis
Efficacy and Safety of Fecal Microbiota Transplantation in Peripheral Psoriatic Arthritis
An abnormal intestinal microbiota may be the mediator of the common inflammatory pathways seen in psoriatic arthritis. This study will explore clinical aspects associated with modifying the intestinal microbiota by infusing fecal…
- Trial name
- FLORA (NCT03058900)
- Testing
- Fecal microbiota transplantation (FMT), Methotrexate (MTX)
- Where
- 2 sites in Denmark
- Volunteers
- 31 people
- Sponsor
- Odense University Hospital
C04.588.274.476.411.307
XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer
XELOX (Capecitabine and Oxaliplatin) is an effective and convenient regimen for patients with metastatic colorectal cancer. Chronomodulated therapy may reduce toxicity.
- Trial name
- NCT00212615
- Testing
- Oxaliplatin (Eloxatin), Capecitabine (Xeloda)
- Where
- 8 sites in Denmark, Sweden
- Volunteers
- 116 people
- Sponsor
- Odense University Hospital
Adenocarcinoma
Taxotere®, Eloxatin® and Xeloda® (TEX) in Combination With Herceptin® as Treatment for HER2 Positive Non-resectable Cancer
The primary aim of this dose-finding study is to determine the maximum tolerated dose of taxotere, eloxatin and capecitabine (TEX) in combination with herceptin given every third week as first-line treatment in patients with…
- Trial name
- NCT01295086
- Testing
- Docetaxel, Oxaliplatin, Capecitabine
- Where
- 4 sites in Denmark
- Volunteers
- 27 people
- Sponsor
- Odense University Hospital
Pain
Influence of Pain on Exercise-induced Hypoalgesia
The purpose of this study is to investigate how acute pain induced by hypertonic saline prior to exercise influence the magnitude of exercise-induced hypoalgesia after a 3 min isometric wallsquat exercise in healthy subjects.
- Trial name
- NCT04354948
- Testing
- Pain (hypertonic saline), No pain (Hypotonic saline)
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Osteoporosis
PTH and Vibration in OSteoporosis Study
Objective: This is a randomized controlled trial (RCT) in osteoporosis patients randomized to standard parathyroid hormone (PTH) treatment alone or to standard PTH treatment and Whole-body vibration (WBV).
- Trial name
- PaVOS (NCT02563353)
- Testing
- whole-body vibration, teriparatide
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease, Ischemic Heart Disease
Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent
The aim of the Danish Organization for Randomized Trials with Clinical Outcome (SORT OUT) is to compare the safety and efficacy of the sirolimus eluting ORSIRO stent and the biolimus-eluting NOBORI stent in a population-based…
- Trial name
- SORT OUT VII (NCT01879358)
- Testing
- Drug-eluting stent
- Where
- Denmark
- Volunteers
- 2,314 people
- Sponsor
- Odense University Hospital
Myeloproliferative Disorders, Pulmonary Hypertension
Pulmonary Hypertension in Patients With Myeloproliferative Neoplasms
This is an observational prospective study aiming to clarify the prevalence of pulmonary hypertension in patients with Myeloproliferative Neoplasms and their prognosis.
- Trial name
- MPNPH (NCT02580903)
- Testing
- Radiology
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Odense University Hospital
Post Herpetic Neuralgia
Acupuncture as Treatment of Post-herpetic Neuralgia: A RCT A Double-blinded Randomized Clinical Trial.
The aim of this study is to perform the first RCT investigating the possible effect of superficial dry-needling (SDN) - a special kind of acupuncture used for PHN. The participants will be divided into two groups.
- Trial name
- NCT03974438
- Testing
- Superficial dry needling / Acupunture
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Treatment of Postmastectomy Pain Syndrome With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post mastectomy pain syndrome. Half of patients will receive fat grafting and the other half of patients will receive sham.
- Trial name
- NCT03081286
- Testing
- Liposuction, Fat graft
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Aortic Valve Stenosis, Diastolic Dysfunction
Danish National Randomized Study on Early Aortic Valve Replacement in Patients With Asymptomatic Severe Aortic Stenosis
The purpose of this study is to examine the impact of early surgery in patients with asymptomatic severe aortic valve stenosis with signs of subclinical LV dysfunction despite preserved LVEF, with a watchfull waiting approach.
- Trial name
- DANAVR (NCT03972644)
- Testing
- Aortic valve replacement
- Where
- Denmark
- Volunteers
- 1,700 people
- Sponsor
- Odense University Hospital
Hematoma, Subdural, Chronic
Chronic Subdural Hematoma - Reduction of Recurrence by Treatment With Angiotensin Converting Enzyme Inhibitors
The project aims at investigating if treatment with the Angiotensin Converting Enzyme inhibitor Coversyl (perindopril) for 3 months after surgery for chronic subdural hematoma will decrease the risc of recurrence.
- Trial name
- KSDH (NCT00915928)
- Testing
- Perindopril
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Lymphedema
Treatment of Breast Cancer Related Lymphedema With Cell-assisted Lipotransfer
Breast cancer is the most common cancer type among women. Treatment in many cases involves axillary lymphadenectomy followed by radiation therapy.
- Trial name
- NCT02592213
- Testing
- Cell-assisted lipotransfer
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Colorectal Cancer, Colorectal Polyp
Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy
Following European guidelines patients undergoing colonoscopy in one of Odense University Hospitals units will now be offered a colon capsule endoscopy (CCE) in case of incomplete examinations.
- Trial name
- SOCRATEC (NCT04307901)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Odense University Hospital
Inflammatory Bowel Diseases, Crohn Disease
The Role of PET/MRI in the Diagnosis and Treatment of Children and Adolescents With Inflammatory Bowel Diseases
The purpose of this study is to test the utility of PET/MRI in diagnosis and management of Inflammatory bowel disease (IBD) in children and adolescents, hereby To test if PET/MRI scan is an accurate method to diagnose and…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- PEDICAD (NCT03640637)
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Odense University Hospital
Liver Fibroses, Alcohol-Induced Disorders
Alcohol Challenge On Liver and Gut Measured by Liver Vein Catheterization. A Pathophysiological Intervention Trial
To investigate the effects of acute alcohol challenge on the gut and liver axis.
- Trial name
- NCT03018990
- Testing
- Ethanol
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Biliary Strictur After Hepatojejunostomy (HJ), Morbidity and Mortality After and Around HJ
Long Time Follow up After HJ Following Iatrogenic Bile Duct Injuries
Introduction: Bile duct injury (BDI) after cholecystectomy remains a serious complication with major implications for patient outcome. For most major BDIs, the recommended method of repair is a hepaticojejunostomy (HJ).
- Trial name
- NCT01447030
- Volunteers
- 139 people
- Sponsor
- Odense University Hospital