Clinical trials: sponsored by Odense University Hospital
Diabetes Mellitus, Diabetic Foot Ulcer
Evaluation of 3D Imaging Ulcer Camera
The aim of the study is to evaluate the intra- and inter-rater variability of wound measurements using the 3D camera and to compare with standard measurement methods (2D image method and gel injection).
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer, Wound, Chronic Disease
- Trial name
- 3D-DFU (NCT03063138)
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Odense University Hospital
Type 2 Diabetes, Hypertension
Individually Tailored Treatment of Type 2 Diabetes
The prevalence of Type 2 diabetes (T2D) is rising rapidly worldwide. In Denmark approximately 8% of adults have T2D and more than 25.000 are diagnosed each year. This has vast consequences for society and the patient.
- Trial name
- ITT (NCT02015130)
- Testing
- Individual treatment
- Where
- 4 sites in Denmark
- Volunteers
- 2,246 people
- Sponsor
- Odense University Hospital
Cancer
Selenium in the Prevention of Cancer
This is a pilot study proceeding an intended international trial. Hypothesis: Daily intake of selenium supplementation in the form of selenium-enriched yeast tablets will reduce the risk of cancer in healthy individuals.
- Trial name
- DK PRECISE (NCT01819649)
- Testing
- SelenoPRECISE selenium-enriched yeast tablet, Pharma Nord Denmark A/S
- Where
- Denmark
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Coronary Arteriosclerosis
Characteristics of Culprit Lesion and Changes in Plaque Composition. A Dual Energy Cardiac CT Study
Identifying patients who are at risk for a future myocardial infarction, is still one of the biggest challenges in cardiology. In this study the investigators will investigate culprit lesion in patients with NSTEMI and the…
- Trial name
- S-20130009 (NCT02639962)
- Testing
- Cardiac CT
- Where
- Denmark
- Volunteers
- 135 people
- Sponsor
- Odense University Hospital
Mitral Valve Regurgitation
Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI)
The preferred treatment of organic mitral regurgitation (MR) is mitral valve repair. Optimally this should be timed so late that it commensurate with the risk of surgery and before irreversibly damage of the heart and pulmonary…
- Trial name
- HEMI (NCT02961647)
- Testing
- Mitral valve repair
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Odense University Hospital
Erectile Function
Ekstracorporal Shock Wave Therapy as a Treatment for Erectile Dysfunction in Men After Prostatectomy
Extra Corporal Shock wave Therapy Has proven effective as treatment with mild to moderate erectile dysfunction in men with erectile dysfunction.
- Trial name
- ESWT (NCT03143790)
- Testing
- Extracorporeal Shockwave Terapy
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Odense University Hospital
Interstitial Lung Diseases, Rheumatoid Arthritis
Fibrocytes in Rheumatoid Arthritis, Asthma and Interstitial Lung-disease.
To study Fibrocytes in patients with Rheumatoid Arthritis, Interstitial lung disease and severe asthma and healthy controls.
- Conditions
- Interstitial Lung Diseases, Rheumatoid Arthritis, Asthma
- Trial name
- NCT02711657
- Testing
- Fibrocyte measurement and lung function test.
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Peptic Ulcer Bleeding
Doppler-guided Endoscopic Treatment in Peptic Ulcer Bleeding
The present study is a randomized controlled trial (RCT) that examines if the outcome of peptic ulcer bleeding could be improved by use of doppler-guided endoscopic treatment.
- Trial name
- NCT02434978
- Testing
- Supplementary endoscopy with doppler-guided therapy, IV. PPI, Endoscopic treatment at primary endoscopy
- Where
- 2 sites in Denmark
- Volunteers
- 125 people
- Sponsor
- Odense University Hospital
COPD
COPD, Inflammation and Rehabilitation
Patients with chronic obstructive pulmonary disease, also known as COPD or emphysema, is like any other with a chronic illness not only affected by the physical discomfort the illness gives.
- Trial name
- NCT01700296
- Testing
- Best care
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Colonoscopy
Comparing Oral Preparation With Macrogol (Moviprep) and Natriumdihydrogenphosphatdihydrat (Phosphoral)
The purpose of this study is to determine whether Moviprep or Phosphoral is the best method of bowel preparation before colonoscopy - seen by the patients and by the endoscopist.
- Trial name
- NCT01705262
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Child, Motor Activity
CHAMPS Eye Study - Myopia and Retinal Vascular Geometry in Relation to Physical Activity
An increasingly physical inactive lifestyle in the Western World has led to a higher number of lifestyle -related diseases. The consequences are now already present in childhood with an increased prevalence of overweight…
- Conditions
- Child, Motor Activity, Myopia
- Trial name
- NCT02346006
- Testing
- More physical activity.
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Migraine With Aura
Women With Migraine With Aura Neuroimaging Study
The purpose of this study is to investigate whether a particular form of migraine, migraine with aura, is associated with structural changes in the brain
- Trial name
- WOMAN (NCT02047695)
- Volunteers
- 345 people
- Sponsor
- Odense University Hospital
Endomyocardial Fibrosis, Aortic Valve Stenosis
Assessment of Myocardial Fibrosis in Aortic STenosis
This observational cohort study studies the impact myocardial fibrosis has on patients with severe aortic stenosis undergoing aortic valve replacement.
- Trial name
- AMFAST (NCT02316587)
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Odense University Hospital
Surgical Wound Infection, Infection; Cesarean Section
Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section
The purpose of this study is to examine whether obese women (BMI >= 30) who give birth by caesarean section have a reduced incidence of wound infection and dehiscence when incisional Negative Pressure Wound Therapy is applied…
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Cesarean Section; Dehiscence, Complications; Cesarean Section
- Trial name
- NCT01890720
- Testing
- iNPWT, Standard postoperative wound dressing
- Where
- 5 sites in Denmark
- Volunteers
- 876 people
- Sponsor
- Odense University Hospital
Pancreatic Cancer
Pancreatic Core Biopsy Needle Study in Patients Suspected of Pancreatic Malignancy
This study evaluates whether a new endoscopic ultrasonography (EUS) histology needle may improve the diagnostic yield during biopsies of pancreatic lesions
- Trial name
- PANCOBE (NCT03016637)
- Testing
- SharkCore (TM) FNB Exchange System
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Leg Ulcer
Treatment of Chronic Leg Ulcers With Autologous Stromal Vascular Fraction
Chronic leg ulcers are associated with decreased quality of life and an increased mortality. In many cases these ulcers are treated conservatively and the healing time can be several months.
- Trial name
- NCT02987101
- Testing
- Liposuction, Standard wound care, Adipose-Derived Regenerative Cells
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Uterine Fibroids, Arterial Embolization
Uterine Fibroid Embolization- Long Term Follow up and Technical Perspectives
The purpose of this prospective non-randomised study is to examine whether two different microspheres (Bead-Block and Embosphere) are equally effective in the treatment of the uterine fibroid controlled with contrast-enhanced MR…
- Trial name
- NCT01852734
- Testing
- embolizations ,uterine fibroid, embolizations
- Where
- 2 sites in Denmark
- Volunteers
- 52 people
- Sponsor
- Odense University Hospital
Surgical Wound Infection, Infection; Cesarean Section
Intervention for Postpartum Infections Following Caesarean Section
The purpose of this study is to examine whether Negative Pressure Wound Therapy is an effective wound treatment compared to conventional wound treatment in the period of time from reoperation to re-suturing in women having…
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Cesarean Section; Dehiscence, Complications; Cesarean Section
- Trial name
- APIPICS (NCT01891006)
- Testing
- Negative Pressure Wound Therapy, Standard wound dressing
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Odense University Hospital
Rheumatoid Arthritis, Cardiovascular Disease
Vitamin D and Cardiovascular Events in Rheumatoid Arthritis
The aim of the study is to evaluate cardiovascular events during long-term follow-up in Rheumatoid Arthritis. The primary outcome "any cardiovascular event" will be evaluated using systematic audits of patient records, and will…
- Trial name
- NCT02932644
- Testing
- Baseline serum vitamin D level below 50 nmol/l, Baseline serum vitamin D level at or above 50 nmol/l
- Volunteers
- 160 people
- Sponsor
- Odense University Hospital
Anorexia Nervosa, Appetite Disorders
Hunger and Satiety in Anorexia Nervosa
Anorexia means loss of appetite. But there is disagreement about whether the appetite is changed by the disease anorexia nervosa (AN).
- Trial name
- HUSAAN (NCT02932046)
- Testing
- Standardized noon meal
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital