Clinical trials: sponsored by Odense University Hospital
Myocardial Infarction [C14.907.585.500]
Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment
The aim of this study was to measure the effect of low- and high-dose lipid-lowering treatment with rosuvastatin on the coronary physiology parameters.
- Trial name
- NCT01245894
- Testing
- Low-dose Rosuvastatin, High-dose Rosuvastatin
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Odense University Hospital
Endothelial Dysfunction, Atherosclerosis
Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Endothelial Function
The aim of this study was to measure the effect of moderate and intensive lipid-lowering treatment with rosuvastatin on the endothelial function.
- Trial name
- NCT01223625
- Testing
- Rosuvastatin 5mg/day, Rosuvastatin 40mg/day
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Odense University Hospital
ST-segment Elevation Myocardial Infarction, Subclinical Carotid Atherosclerosis
Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT)
The aim of this study was to measure the effect of moderate and intensive lipid-lowering treatment with rosuvastatin on the carotid intima-media thickness (CIMT) as a surrogate marker of cardiovascular risk.
- Trial name
- NCT01203982
- Testing
- Rosuvastatin
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Odense University Hospital
Osteopetrosis
Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5
The aim of the study is to describe patients with a high bone mass phenotype due to a mutation in the low density lipoprotein l receptor 5 gene (LRP5) and compare them with age and sex matched controls.
- Trial name
- NCT01199094
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Endoscopy, Digestive System, Esophageal Neoplasms
Endoscopic Submucosal Dissection in Upper Gastrointestinal Canal With HybridKnife
Endoscopic submucosal dissection (ESD) is a relatively new modality for the treatment of superficial gastrointestinal neoplasia and especially in the diagnosis and treatment of submucosal tumors.
- Conditions
- Endoscopy, Digestive System, Esophageal Neoplasms, Stomach Neoplasms
- Trial name
- NCT01185483
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Pulmonary Disease, Chronic Obstructive
Antibiotics in Chronic Obstructive Pulmonary Disease (COPD)
It is not clear whether antibiotic therapy is needed in patients with mild to moderate exacerbation of chronic obstructive lung disease.
- Trial name
- TAExaCOP (NCT00952861)
- Testing
- Doxycycline
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Acute Myocardial Infarction
Treatment of Myocardial Infarction With Bone Marrow Derived Stem Cells
The aim of the study is to investigate whether infusion of autologous bone marrow derived stem cells can improve cardiac function in the aftermath of a myocardial infarction.
- Trial name
- NCT00275977
- Testing
- Coronary catherization and stem cell infusion
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Ischemia
Treatment of Severe Limb Ischemia With Autologous Bonemarrow Derived Mononuclear Cells
The aim of the study is to investigate whether implantation of autologous bone marrow derived stem cells in ishemics limbs will improve vascularization
- Trial name
- DANCELL-CLI (NCT00442143)
- Testing
- Stem cell implantation
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus
Comparison of Coronary Xience V and the Cypher Select+ Stents in Diabetic Patients
In stent neointimal hyperplasia may be less in the Cypher select plus stent compared to the Xience V stent in diabetic patients.
- Trial name
- DIABEDES IV (NCT00552994)
- Testing
- Cypher Select plus, Xience V stent
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Femoral Neck Fracture
Postoperative Analgesia With Local Infiltration After Femoral Neck Fracture
Reducing pain is an essential factor for early mobilization after osteosynthesis of femoral neck fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT00529425
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease, Arteriosclerosis
Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension.
- Conditions
- Coronary Artery Disease, Arteriosclerosis, Carotid Stenosis, Thrombosis
- Trial name
- NCT01106573
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Critical Illness, Length of Stay
Advantages and Disadvantages of Long Term Sedation in Intensive Care Unit Patients
The purpose of the study is to determine whether sedation of the critical ill patient prolongs the time receiving mechanical ventilation.
- Conditions
- Critical Illness, Length of Stay, Respiration, Artificial, Intensive Care Units
- Trial name
- NCT00466492
- Testing
- Sedation or no sedation during mechanical ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Acute Coronary Syndrome
Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Plaque Composition in Patients With ST-Segment Elevation Myocardial Infarction (MI)
In patients with ST-segment elevation acute myocardial infarction (STEMI) increased LDL-cholesterol reduction (rosuvastatin 40 mg) will provide incremental plaque stabilization (changes in plaque composition) and plaque…
- Trial name
- VIRHISTAMI (NCT01058915)
- Testing
- Rosuvastatin 5mg, Rosuvastatin 40mg
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Odense University Hospital
Polyneuropathy
Imipramine and Pregabalin Combination in Painful Polyneuropathy
Polyneuropathy of different etiologies is often associated with pain and the standard treatment for this type of pain is gabapentinoids or antidepressants.
- Trial name
- NCT01047488
- Testing
- Imipramine, Pregabalin, Imipramine, pregabalin
- Where
- 3 sites in Denmark
- Volunteers
- 75 people
- Sponsor
- Odense University Hospital
Painful Polyneuropathy
Levetiracetam for Painful Polyneuropathy
Polyneuropathy of different etiologies is often associated with pain. The standard treatment of this pain is anticonvulsants or antidepressants, but none of these treatment are effective or tolerable for all patients.
- Trial name
- NCT00286260
- Testing
- levetiracetam
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Multiple Sclerosis
Levetiracetam in Central Pain in Multiple Sclerosis(MS)
Multiple sclerosis is often associated with pain. There is no standard treatment of this type of pain. Levetiracetam is a new anticonvulsant and it is the hypothesis that it could relieve central pain in multiple sclerosis.
- Trial name
- NCT00423527
- Testing
- levetiracetam
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Lymph Nodes, Esophageal Cancer
Interobserver Agreement of Endoscopic Ultrasonography and Endoscopic Sonoelastography in the Evaluation of Lymph Nodes
Endoscopic ultrasound (EUS) is an important part of the pre-treatment evaluation of patients with upper gastrointestinal tract cancer (esophageal, gastric, pancreatic and liver cancer).
- Conditions
- Lymph Nodes, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT01033695
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Dyspepsia
Proton Pump Inhibitor Treatment Stop
The purpose of this study is to determine how many chronic users of antisecretory medication can stop after a test for a bacteria associated with peptic ulcer disease. This is evaluated in a discontinuation trial.
- Trial name
- NCT00120315
- Testing
- esomeprazole, Helicobacter pylori c-13 breath test
- Where
- Denmark
- Volunteers
- 171 people
- Sponsor
- Odense University Hospital
Hypogonadism, Metabolic Syndrome
Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men
The purpose of this study is to determine the effect of training and testim on Hypogonadism.
- Trial name
- NCT00700024
- Testing
- Testim, Strength training
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Ischemic Heart Disease, Coronary Atherosclerosis
The SOURT OUT IV TRIAL
In a randomized study the Xience V coroary artery stent may be non inferior to the Cypher Select+ coronary stents in the treatment of unselected patients with coronary artery disease.
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Percutaneous Coronary Intervention
- Trial name
- SORT OUT IV (NCT00552877)
- Testing
- Percutaneous coronary intervention (Xience V stent)
- Where
- Denmark
- Volunteers
- 2,678 people
- Sponsor
- Odense University Hospital