Clinical trials: sponsored by Odense University Hospital
Bone Diseases
Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish Men
Objective: To define a reference-population of healthy young men (20-29 years old). To establish reference-intervals for: 1. Total, bioavailable and free serum androgens (testosterone, dihydrotestosterone, androstenedione) and…
- Trial name
- NCT00150163
- Where
- Denmark
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Benign Solitary Solid, Cystic Thyroid Nodules
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion.
- Trial name
- NCT00150150
- Testing
- Interstitial laser photocoagulation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Hirsutism, Type 2 Diabetes
Prospective Study of Patients With Hirsutism
Hirsutism is the presence of terminal hairs in a male-like pattern in females, due to elevated male hormone levels. Females with hirsutism are often overweight and have metabolism disturbances as insulin resistance and impaired…
- Conditions
- Hirsutism, Type 2 Diabetes, Polycystic Ovary Syndrome
- Trial name
- NCT00145288
- Where
- Denmark
- Volunteers
- 340 people
- Sponsor
- Odense University Hospital
Anorexia Nervosa, Eating Disorder
Funen Anorexia Nervosa Study - Retrospective Cohort Study and 10 Year Follow-up Study
The aim of the study are: 1. Retrospectively to study the clinical characteristics and features (somatic, psychological and social variables) of patients treated in Center for Eating Disorders, Odense University Hospital…
- Trial name
- NCT00267228
- Where
- Denmark
- Sponsor
- Odense University Hospital
Type 2 Diabetes Mellitus
Prevalence of Macrovascular Disease in Type 2 Diabetes Mellitus
The study aim is to establish a consecutive population of newly referred type 2 diabetes mellitus patients and among these to describe the degree of macrovascular disease by evaluating left ventricular systolic and diastolic…
- Trial name
- NCT00298844
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Odense University Hospital
Healthy
OXY-2: The Pharmacogenetics of Oxycodone Analgesia in Human Experimental Pain Models
Thirty-two healthy volunteers will be submitted to experimental pain and on the 2 study days receive Oxycodone 20 mg po vs. placebo.
- Trial name
- NCT00271973
- Testing
- Oxycodone
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type 1 Diabetes Mellitus
Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose
The main purpose of the study is to investigate the reason for the reduced number of hypoglycaemic attacks in type 1 diabetic patients when, for a period of time, using Insulin Aspart at meals together with NPH insulin mornings…
- Trial name
- NCT00145353
- Testing
- Insulin NovoRapid versus Actrapid
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Odense University Hospital
Graves´ Disease, Thyroid Associated Ophthalmopathy
Rituximab in the Treatment of Graves' Disease
Aim: In a phase II pilot study encompassing 20 patients with Graves' disease to evaluate the effect of rituximab: 1. Biochemically as assessed by markers of disease activity ( free T4, free T3, TSH, TSH-receptor antibodies…
- Trial name
- NCT00150111
- Testing
- Methimazole, Rituximab, Immunization with various vaccines
- Where
- 2 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Ulcerative Colitis
Treatment of Ulcerative Colitis With a Combination of Lactobacillus Rhamnosus and Lactobacillus Acidophilus.
In this trial we test the hypothesis that a probiotic containing Lactobacillus acidophilus and Lactobacillus rhamnosus is an effective therapy for patients with ulcerative colitis.
- Trial name
- NCT00374725
- Testing
- Administration of probiotic (L. rhamnosus and L. acidophilus)
- Where
- 2 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Odense University Hospital
Crohn's Disease
Treatment With Lactobacillus Rhamnosus and Lactobacillus Acidophilus for Patients With Active Colonic Crohn's Disease.
The purpose of this study is to determine whether a probiotic containing Lactobacillus Acidophilus and Lactobacillus Rhamnosus is effective as treatment for patients with active colonic Crohn's disease
- Trial name
- NCT00374374
- Testing
- Administration of probiotic
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Acromegaly
Comparable Effects of Lanreotide Autogel and Octreotide LAR on GH, IGF-I Levels and Patient Satisfaction
The morbidity and the mortality in acromegalic patients closely correspond to growth hormone (GH) levels and therefore efficient long-term treatment is important.
- Trial name
- NCT00145405
- Testing
- Lanreotide Autogel and Octreotide LAR
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Toxic Nodular Goitre, Graves Disease
Antithyroid Drugs During Radioiodine Therapy
Background: The use of radioactive iodine (131I) therapy as the definite cure of hyperthyroidism is widespread. According to a survey on the management of Graves' disease, thirty per cent of physicians prefer to render their…
- Trial name
- NCT00150137
- Testing
- Methimazole
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Odense University Hospital
Bone Diseases, Metabolic Syndrome
Odense Androgen Study in the Elderly
Introduction Male ageing is associated with sarcopenia, frailty, osteopenia, obesity, the metabolic syndrome and cardiovascular disease. To what extent the androgens affect these signs of ageing is still largely undetermined.
- Trial name
- NCT00155961
- Where
- Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pulmonary Disease, Chronic Obstructive
Prophylactic Antibiotic Treatment of Patients With Chronic Obstructive Lung Disease (COLD)
The purpose of the study is to investigate, in patients with moderate to severe chronic obstructive lung disease, whether intermittent antibiotic treatment leads to: A slower rate of decline in forced expiratory volume in one…
- Trial name
- NCT00132860
- Testing
- azithromycin
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Odense University Hospital
Alcoholic Liver Cirrhosis, Ascites
Prevention of Decompensation in Liver Cirrhosis
The purpose of this study is to determine whether losartan, an angiotensin II blocker prevents the sodium retention in patients with liver cirrhosis and by that reduces the fluid retention.
- Trial name
- NCT00239096
- Testing
- losartan (drug)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Stroke, Transient Ischemic Attack
Smoking Cessation Intervention After Stroke or Transient Ischaemic Attack.
Patients with stroke or transient ischemic attach should receive advise on smoking cessation. It is however unknown if an intensive smoking cessation program is better than ordinary advise on smoking cessation during…
- Trial name
- NCT00228098
- Testing
- Smoking cessation
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Hypertension
Observational Study of the Prognosis in Treated Arterial Hypertension
Observational study of life time prognosis for persons medically treated for arterial hypertension, according to current WHO-guidelines.
- Trial name
- NCT00225030
- Testing
- antihypertensive drugs according to current guidelines
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Odense University Hospital
Colorectal Cancer
Patients Preference for Oral or i.v. Therapy
Until recently, bolus 5-flourouracil (FU) + folinic acid (FA) has been considered the standard chemotherapy for patients with colorectal cancer. Several studies have shown that Capecitabine is as effective as Mayo regimen.
- Trial name
- NCT00212589
- Testing
- Capecitabine, Fluorouracil + folinic acid
- Where
- 4 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital