Clinical trials: sponsored by Odense University Hospital
Binge-Eating Disorder, Quality of Life
Quality of Life in Binge Eating Disorder.
Binge Eating Disorder (BED) patients tend to report low quality of life (Qol). However, research is limited. Most research on Qol in BED include generic measures, rather than disease specific.
- Trial name
- NCT05010798
- Where
- 2 sites in Denmark
- Volunteers
- 98 people
- Sponsor
- Odense University Hospital
Psoriasis Vulgaris
Improvement of Psoriasis Patients' Adherence to Topical Drugs
Psoriasis affects 2-4% of the Western adult population and is a socio-economic burden for patients and society. Topical drugs are recommended as first-line treatment for mild-to-moderate psoriasis, but low adherence is a barrier…
- Trial name
- NCT04220554
- Testing
- Improved support by health-care professionals
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- Odense University Hospital
Tourniquet and Outcome After Total Knee Replacement
The Effect of the Tourniquet in Bilateral Total Knee Replacement
This study describes in a randomised controlled trial how the tourniquet influence the outcome af a total knee replacements
- Trial name
- NCT06228651
- Testing
- Tourniquet, The leg without the tourniquet
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Breastmilk Expression, Collection, Breastmilk
Antenatal Breastmilk Expression From Week 34 of Gestation
In this pilot study, the investigators aim to examine if antenatal breastmilk expression from week 34 of pregnancy is a safe and feasible procedure for the mother and fetus.
- Conditions
- Breastmilk Expression, Collection, Breastmilk, Breastfeeding, Healthy
- Trial name
- EXPRESS-MOM (NCT05516199)
- Testing
- Antenatal breastmilk expression, Breastfeeding consultation
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Frailty, Cancer
Predictive Value of Geriatric Oncology Screening and Geriatric Assessment in Older Patients With Solid Cancers
A Randomized Clinical Trial examining the effects of Comprehensive Geriatric Assessment as an add on to oncologic treatment. Participants included are cancer patients found eligible for oncologic treatment, age 70 or more, and…
- Conditions
- Frailty, Cancer, Age
- Trial name
- PROGNOSIS-RCT (NCT04686851)
- Testing
- Comprehensive Geriatric Assessment and follow-up
- Where
- Denmark
- Volunteers
- 322 people
- Sponsor
- Odense University Hospital
Birch Pollen Allergy, Allergic Rhinoconjunctivitis
S.C. Immunotherapy With BM41 in Patients With Allergic Rhino-conjunctivitis Caused by Birch Pollen
The aim of this clinical phase I single centre, randomized, double-blind, placebo-controlled study with open comparator is to investigate tolerability and safety as well as the immunological effects of BM41 in comparison to…
- Trial name
- BM41 (NCT04912076)
- Testing
- BM41, ALK Alutard SQ Betula verrucosa
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Cardiac Toxicity, Lung Cancer Stage III
COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA)
Patients with loco-regional NSCLC planned for curative treatment with chemoradiotherapy will be invited to participate in a prospective study; besides routine treatment, the patients will be followed with an ECG and cardiac MR…
- Conditions
- Cardiac Toxicity, Lung Cancer Stage III, Lung Cancer Stage II, Radiation Toxicity
- Trial name
- COLA (NCT05258448)
- Testing
- Chemoradiotherapy
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Radiodermatitis, Breast Neoplasms
Patient Reported Outcomes Using Mepitel Film During Radiotherapy
Breast cancer patients in post-operative radiotherapy (RT) often experience acute skin reactions like erythema, pain, itching and oversensitivity.
- Conditions
- Radiodermatitis, Breast Neoplasms, Side Effect
- Trial name
- NCT06133218
- Testing
- Mepitel Film
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital
Solid Carcinoma, Frailty
Geriatric Oncology Screening of Older Patients With Solid Cancers
Older patients with cancer constitute a heterogeneous group with varying comorbidity; therefore, geriatric assessment with initial screening is recommended. The Geriatric 8 (G8) has been established as a promising screening tool.
- Conditions
- Solid Carcinoma, Frailty, Age, Geriatrics
- Trial name
- PROGNOSIS-G8 (NCT04644874)
- Testing
- Geriatric 8, modified Geriatric 8, 30 second chair stand test
- Where
- Denmark
- Volunteers
- 1,401 people
- Sponsor
- Odense University Hospital
Alcoholic Liver Disease, Liver Cirrhosis, Alcoholic
Profermin®: Prevention of Progression in Alcoholic Liver Disease by Modulating Dysbiotic Microbiota
Investigators wishes to influence the gut microbiota in patients with alcoholic liver disease in a randomized controlled clinical trial.
- Conditions
- Alcoholic Liver Disease, Liver Cirrhosis, Alcoholic, Probiotics, Liver Fibrosis
- Trial name
- SYN-ALD (NCT03863730)
- Testing
- Profermin Plus, FSMP, probiotics, Fresubin, dietary supplement
- Where
- 2 sites in Denmark
- Volunteers
- 56 people
- Sponsor
- Odense University Hospital
Health Effects of Aronia
Potential Health Effects of Aronia Intake
Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months.
- Trial name
- NCT03405753
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pulmonary Embolism, Pulmonary Embolus/Emboli
Point-of-care Ultrasound in Suspected Pulmonary Embolism
Pulmonary embolism (PE) is a common cardiovascular condition with an estimated incidence of 0.60 to 1.12 per 1000 inhabitants in the United States of America, and the diagnosis is challenging as patients with PE present with a…
- Trial name
- NCT04882579
- Testing
- Point-of-care-ultrasound examination
- Where
- 5 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Sperm Antibodies, Sex Ratio
Effects of Male-specific Antibodies on Sex Ratio
Investigation of the ability of antibodies from vasectomized men in binding to Y-spermatozoa as a possible explanation of the lower sex ratio observed after microinsemination using epididymal sperm from vasectomized men.
- Trial name
- NCT02267252
- Testing
- Antibody-sperm binding
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Azoospermia, Nonobstructive
The Potential of Sperm Retrieved by Micro-TESE to Fertilize Vitrified/Warmed Oocytes
Couples referred for microdissection-TESE (m-TESE) due to Klinefelter's syndrome, maturation stop in the spermatogenesis, or failed retrieval of testicular spermatozoa by conventional techniques with needle or TruCut are…
- Trial name
- NCT03809026
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Glaucoma
AADI Glaucoma Shunt - a Quality Control Study
To prospectively investigate the effect and safety of implantation of the AADI glaucoma tube in eyes with medically intractable glaucoma in the period 2019 to 2020, at the Department of Ophthalmology, Odense University Hospital.
- Trial name
- NCT03850054
- Testing
- AADI glaucoma shunt
- Where
- Denmark
- Volunteers
- 3 people
- Sponsor
- Odense University Hospital
Endometrial Receptivity
Modification of Endometrial Receptivity After Vaginal Seminal Plasma Application
The aim of the project is to investigate the effect of seminal plasma on the endometrium and to evaluate changes in the endometrial receptivity after exposure to seminal plasma.
- Trial name
- NCT04286425
- Testing
- seminal plasma, saline solution
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Endometrial Receptivity, Fertility
Endometrial Markers in Autoimmune Diseases
Autoimmune diseases cause a decreased endometrial receptivity during the implantation window, most likely changing the endometrial cytokines pattern due to dysregulation of the inflammatory processes.Therefore, endometrial…
- Conditions
- Endometrial Receptivity, Fertility, Autoimmune Diseases
- Trial name
- NCT03843034
- Testing
- Measure endometrial markers
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Odense University Hospital
Osteoporosis
Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE)
The Risk-stratified Osteoporosis Strategy Evaluation Study (ROSE) is a randomised population-based study, including 20,904 Danish women aged 65-80 years, investigating the effectiveness of a two-step screening programme for…
- Trial name
- ROSE (NCT01388244)
- Testing
- Screening, Control
- Where
- Denmark
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Osteoporosis Secondary, Diabetes Mellitus, Type 1
the Type ONe dIabetic Bone Collaboration Study
In this cross-sectional clinical study, we will examine the bones of 111 Type 1 Diabetes (T1D) patients and 37 age-matched healthy controls with the aim of describing a T1D Bone Phenotype.
- Trial name
- TONICS (NCT05673837)
- Where
- Denmark
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cardiovascular Diseases, Particulate Matter Inhalation Injury
Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality - the AIRCARD Study.
The purpose of this study is to determine the impact of individually lifetime accumulated exposure to air and noise pollution on the incidence and prevalence of cardiovascular diseases (CVD) and mortality.
- Conditions
- Cardiovascular Diseases, Particulate Matter Inhalation Injury, Arteriosclerosis, Pollution; Exposure
- Trial name
- AIRCARD (NCT04353232)
- Where
- Denmark
- Volunteers
- 33,723 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital