Clinical trials: sponsored by Ohio State University
Postoperative Pain
Effect of Root Canal Treatment (Versus no Treatment) for Patients With Tooth Infections and Toothaches
The purpose of this study is to evaluate patients with emergency pain and a sore (infected) tooth to determine if immediate root canal therapy is better at reducing pain, when compared to initial treatment with antibiotic and…
- Trial name
- NCT01870973
- Testing
- root canal treatment, anesthesia, pain medications, and antibiotic, no root canal treatment, anesthesia, pain medications, and antibiotic
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Ohio State University
Ovarian Cancer, Fallopian Tube Cancer
Study of Gemcitabine/Carboplatin/Bevacizumab to Treat Ovarian, Fallopian Tube or Primary Peritoneal Cancer
The purpose of this study is to test the effectiveness, safety and tolerability of the drug combination: gemcitabine, carboplatin and bevacizumab in patients that have been diagnosed with platinum sensitive recurrent ovarian…
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- NCT00267696
- Testing
- Bevacizumab, Gemcitabine, Carboplatin
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Melanoma
Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma
The purpose of this study is to determine the safety, tolerability and dose limiting toxicities (DLTs) of VELCADE when administered in combination with interferon-alpha-2b (IFN-α-2b) to patients with metastatic malignant melanoma.
- Trial name
- NCT01462773
- Testing
- Bortezomib, Interferon Alfa-2b
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Prediabetes, Overweight
Evaluation of a Lifestyle Intervention for Employees With Prediabetes
The purpose of this study is to evaluate the impact of a worksite lifestyle intervention for diabetes prevention among employees with prediabetes.
- Conditions
- Prediabetes, Overweight, Obese
- Trial name
- NCT01682954
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Ohio State University
Breast Cancer, Depression
Hatha Yoga in Improving Physical Activity, Inflammation, Fatigue, and Distress in Breast Cancer Survivors
RATIONALE: Yoga may improve inflammation, fatigue, and depression in female breast cancer survivors. PURPOSE: This randomized clinical trial is studying how well Hatha yoga works in improving physical activity, inflammation…
- Conditions
- Breast Cancer, Depression, Fatigue, Pain
- Trial name
- NCT00486525
- Testing
- Yoga Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Anesthetic Effectiveness
Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to the tooth as a supplemental injection, works very well following a…
- Trial name
- NCT01567839
- Testing
- Mandibular buccal Infiltration injection
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Malignant Neoplasm
Ondansetron Versus Palonosetron Antiemetic Regimen Prior to Highly Emetogenic Chemotherapy(HEC)
Palonosetron is different from ondansetron because it stays in the body longer and may prevent nausea and vomiting for a longer period of time than ondansetron.
- Trial name
- NCT01640340
- Testing
- aprepitant, palonosetron hydrochloride, ondansetron
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Substance Abuse
Evaluation of Treatments for Homeless Youths
Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population.
- Trial name
- NCT01143792
- Testing
- Community Reinforcement Approach (CRA) + HIV prevention, Case Management + HIV Prevention, Motivational Enhancement Therapy (MET) + HIV prevention
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Ohio State University
Substance Abuse
Stage 1 Treatment Development With Homeless Mothers
Aim 1. Identify specific targets and processes of intervention among homeless substance abusing mothers with children between the ages of 2 and 6 years from information collected in focus groups and assessment interviews.
- Trial name
- NCT01193114
- Testing
- Ecologically Based Treatment (EBT), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University
Inflammation
Fish Oil (Omega 3), Immune Function, and Mood
This study is designed to examine the effects of fish oil on immune function and mood.
- Trial name
- NCT00385723
- Testing
- Omega 3 (Fish Oil) Supplementation
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Diabetes Mellitus
Transitioning Open Heart Surgery Patients From Insulin Infusions to Detemir
In this study we will determine the proper method for transitioning patients from a continuous insulin infusion to periodic injections of a newer long-acting insulin called detemir (Levemir).
- Trial name
- NCT00717288
- Testing
- Detemir
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Ohio State University