Clinical trials: sponsored by Ohio State University Comprehensive Cancer Center
Breast Cancer, Cervical Cancer
Ohio Patient Navigator Research Program
The Ohio Patient Navigator Research Program (OPNRP) proposes to alleviate disparities in relation to the timely diagnosis and treatment of breast, cervical and colorectal cancer in Columbus, OH.
- Conditions
- Breast Cancer, Cervical Cancer, Colon Cancer, Rectal Cancer
- Trial name
- OPNRP (NCT01569672)
- Testing
- Patient Navigator matched with subject, Subjects are mailed informational/educational materials
- Where
- United States
- Volunteers
- 941 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer
This phase I trial studies how well lorcaserin works in treating chemotherapy-induced peripheral neuropathy in patients with stage I-IV gastrointestinal or breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT04205071
- Testing
- Lorcaserin, Lorcaserin Hydrochloride, Questionnaire Administration
- Sponsor
- Ohio State University Comprehensive Cancer Center
Gastrointestinal Cancer, Neuroendocrine Carcinoma
Inhaled Essential Oil Effect on Common QOL Concerns During Cancer Treatment
This single-blind, randomized controlled trial studies how well inhaled essential oils work for common quality of life concerns in patients who are undergoing cancer treatment such as chemotherapy, targeted therapy, and/or…
- Conditions
- Gastrointestinal Cancer, Neuroendocrine Carcinoma, Skin Cancer
- Trial name
- NCT03858855
- Testing
- Aromatherapy and Essential Oils, Subject Diary
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hospitalization, Malignant Neoplasm
Checklist Tool in Engaging Patients in the Discharge Planning Process
This clinical trial studies how well a checklist tool works in engaging patients in the discharge planning process. Engaging patients in the discharge process may increase participation in the discharge process and improve…
- Conditions
- Hospitalization, Malignant Neoplasm, Transitional Care Planning
- Trial name
- TEPID (NCT02942524)
- Testing
- Communication Intervention, Questionnaire Administration, Survey Administration
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Healthy, Obesity
Communication & Peer Support Effects on Physical Activity in Overweight Postmenopausal Women
This randomized clinical trial studies the feasibility of tailored physical activity intervention that is administered using Interactive Voice Response technology and cell phones.
- Conditions
- Healthy, Obesity, Postmenopausal
- Trial name
- BePHIT (NCT01940016)
- Testing
- communication intervention, exercise intervention
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Anxiety, Depression
iPad Use in Reducing Anxiety and Depression in Patients Undergoing Bone Marrow Transplant
This randomized clinical trial studies iPad use in reducing anxiety and depression in patients undergoing bone marrow transplant.
- Conditions
- Anxiety, Depression, Malignant Neoplasm
- Trial name
- BUCKiPAD (NCT02378012)
- Testing
- Computer-Assisted Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Major Depressive Disorder
Computerized Cognitive Behavior Therapy in Treating Depression in Patients With Cancer
This randomized clinical trial studies how well a computerized cognitive behavior therapy program works in treating depression in patients with cancer.
- Trial name
- NCT02837887
- Testing
- Computerized Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Multiple Myeloma, Plasma Cell Neoplasm
Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of multiple myeloma by blocking blood flow to the cancer.
- Trial name
- NCT00729118
- Testing
- lenalidomide, vorinostat
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer
Testing Interventions to Motivate and Educate
This study is being done to see if teaching physicians and people who are at least 50 years old and have not been screened within guidelines for colorectal cancer about the importance of colorectal cancer screening will increase…
- Trial name
- TIME (NCT01568151)
- Testing
- Clinic-directed intervention program, Individual Patient-Directed Program
- Where
- United States
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hematopoietic Cell Transplantation Recipient, Recurrent Plasma Cell Myeloma
Study of Personalized Melphalan Dosing in the Setting of Autologous Transplant
This randomized phase II trial studies the side effects and how well melphalan hydrochloride works in treating patients with multiple myeloma that has come back or does not respond to treatment.
- Conditions
- Hematopoietic Cell Transplantation Recipient, Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
- Trial name
- NCT03328936
- Testing
- Laboratory Biomarker Analysis, Melphalan Hydrochloride, Pharmacological Study
- Where
- United States
- Sponsor
- Ohio State University Comprehensive Cancer Center
Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage I Squamous Cell Carcinoma of the Oropharynx
Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors
This pilot clinical trial studies freeze-dried black raspberries (BRB) in preventing oral cancer recurrence in high at-risk Appalachian patients previously treated with surgery for oral cancer.
- Conditions
- Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage I Squamous Cell Carcinoma of the Oropharynx, Stage I Verrucous Carcinoma of the Oral Cavity, Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity
- Trial name
- NCT01504932
- Testing
- BRB Lozenge, Survey Administration, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma, Salivary Gland Squamous Cell Carcinoma
Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.
This randomized phase I/II trial studies the side effects and best way to give lyophilized black raspberries in preventing oral cancer in high-risk patients previously diagnosed with stage I-IV or in situ head and neck cancer.
- Conditions
- Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma, Salivary Gland Squamous Cell Carcinoma, Stage 0 Hypopharyngeal Cancer, Stage 0 Laryngeal Cancer
- Trial name
- NCT01469429
- Testing
- laboratory biomarker analysis, questionnaire administration, chemoprevention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Head and Neck Cancer
Pemetrexed Chemotherapy in Poor-Risk Patients With Advanced Head and Neck Cancer
This study will estimate overall response rate of pemetrexed in poor risk patients with advanced, metastatic, or recurrent squamous cell carcinoma of the head and neck.
- Trial name
- NCT00293579
- Testing
- Pemetrexed
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Lip and Oral Cavity Squamous Cell Carcinoma, Oral Cavity Verrucous Carcinoma
Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care
This clinical trial studies direct visual fluorescence in finding oral cancer in high-risk patients and patients undergoing routine dental care.
- Conditions
- Lip and Oral Cavity Squamous Cell Carcinoma, Oral Cavity Verrucous Carcinoma, Stage 0 Lip and Oral Cavity Cancer, Tongue Cancer
- Trial name
- NCT01816841
- Testing
- fluorescence imaging, biopsy, examination
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Plasma Cell Myeloma
Daratumumab in Treating Patients With Multiple Myeloma
This phase II trial studies the side effects and how well daratumumab works in treating patients with multiple myeloma when the infusion is accelerated.
- Trial name
- NCT02944565
- Testing
- Daratumumab
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cancer Survivor, Overweight
Nutrition and Exercise Trial: Improving Diet and Physical Activity Patterns in Overweight Cancer Survivors
This randomized phase II trial will enroll overweight cancer survivors. Subjects in both groups will be educated to follow a diet pattern similar to what is recommended by the Dietary Guidelines for Americans and the American…
- Trial name
- NExT (NCT03489213)
- Testing
- Dietary Intervention, Exercise Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cancer Survivor
Harvesting Health Program in Improving Diet and Physical Activity Level in Cancer Survivors
This pilot clinical trial studies the Harvesting Health Program in improving the diet and physical activity level of cancer survivors.
- Trial name
- NCT02268188
- Testing
- education, nutrition intervention, exercise intervention
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Stage I Prostate Cancer, Stage IIA Prostate Cancer
Tangerine or Red Tomato Juice in Treating Patients With Prostate Cancer Undergoing Surgery
This randomized pilot clinical trial compares tangerine and red tomato juice in treating patients with prostate cancer undergoing surgery.
- Conditions
- Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer, Stage III Prostate Cancer
- Trial name
- NCT02144649
- Testing
- dietary intervention (tangerine tomato juice), dietary intervention (red tomato juice), questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Atypical Ductal Breast Hyperplasia, BRCA1 Gene Mutation
Pilot Study of Curcumin for Women With Obesity and High Risk for Breast Cancer
This randomized pilot clinical trial studies a nanoemulsion formulation of curcumin in reducing inflammatory changes in breast tissue in obese women at high risk for breast cancer.
- Conditions
- Atypical Ductal Breast Hyperplasia, BRCA1 Gene Mutation, BRCA2 Gene Mutation, Ductal Breast Carcinoma in Situ
- Trial name
- NCT01975363
- Testing
- curcumin, Biomarker analysis, Assessment of Dietary Intake
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Dietary Fish and Omega 3 Fatty Acids for Breast Cancer Prevention
Research studies show that the type of fat in the diet may affect breast cancer risk. Fish oil and fish contain increased amounts of omega 3 fatty acids which appear to stop or slow down the growth and development of breast…
- Trial name
- NCT01282580
- Testing
- Lovaza-Omega 3 fatty acid capsules, Dietary fish (canned salmon, albacore)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center