Clinical trials: completed, sponsored by Ohio State University Comprehensive Cancer Center
Recurrent Prostate Cancer, Stage IV Prostate Cancer
Soy Isoflavones in Treating Patients With Recurrent Prostate Cancer or Rising Prostate-Specific Antigen
RATIONALE: Eating a diet high in soy foods may lower the risk of some types of cancer. Isoflavones are compounds found in soy food that may prevent cancer.
- Trial name
- NCT01682941
- Testing
- Arm I Soy Bread, Arm II Soy-Almond Bread
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Advanced Lung Carcinoma, Extensive Stage Lung Small Cell Carcinoma
Resiliency Among Older Adults Receiving Lung Cancer Treatment
This trial studies how well physical therapy and progressive muscle relaxation works in improving physical performance and mood in older patients with stage IIIA-B or IV lung cancer who are undergoing treatment.
- Conditions
- Advanced Lung Carcinoma, Extensive Stage Lung Small Cell Carcinoma, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8
- Trial name
- ROAR-LCT (NCT04229381)
- Testing
- Physical Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Cancer, Mortality
Dietary Patterns, Metabolomics and Colorectal Cancer Risk
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in American men and women with ≥130,000 new cases each year.
- Trial name
- NCT03364582
- Testing
- Observed dietary pattern
- Volunteers
- 173,230 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Human Papillomavirus-Related Carcinoma
Human Papillomavirus Education Programs
This clinical trial aims to implement a culturally-tailored educational outreach actives with the goal of increasing knowledge of human papillomavirus (HPV) types that can lead to cancer and uptake of the available vaccine.
- Trial name
- NCT04880837
- Testing
- Educational Intervention, Informational Intervention, Survey Administration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Advanced Lung Carcinoma, Metastatic Lung Carcinoma
A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer
This phase IIb trial studies the effect of a biobehavioral/cognitive (ABC) treatment on stress, depression, and anxiety in patients with stage IV lung cancer.
- Conditions
- Advanced Lung Carcinoma, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8
- Trial name
- NCT05342571
- Testing
- Behavioral, Psychological or Informational Intervention, Biospecimen Collection, Electronic Health Record Review
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast, Cervical or Colorectal Cancer Screening Needed
Rural Interventions for Screening Effectiveness
This randomized clinical trial studies how well a tailored interactive digital versatile disc (DVD) with or without patient navigation works in improving screening rates in rural women for breast cancer, cervical cancer or…
- Trial name
- RISE (NCT02795104)
- Testing
- Educational Intervention via brochure, Educational Intervention via DVD, Educational Intervention-DVD & Telephone Based Navigation
- Where
- 2 sites in United States
- Volunteers
- 985 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Recurrent Rectal Cancer, Stage IIA Rectal Cancer
Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer
This phase I trial studies the side effects and best dose of trametinib when given together with fluorouracil and radiation therapy before surgery in treating patients with stage II-III rectal cancer.
- Conditions
- Recurrent Rectal Cancer, Stage IIA Rectal Cancer, Stage IIB Rectal Cancer, Stage IIC Rectal Cancer
- Trial name
- NCT01740648
- Testing
- trametinib, fluorouracil, radiation therapy
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Obesity, Endometrial Carcinoma
Gentle Yoga and Dietary Counseling in Improving Physical Function and Quality of Life in Stage I-II Endometrial Cancer Survivors
This randomized clinical trial studies how well gentle yoga and dietary counseling lifestyle change effects physical function and quality of life of endometrial cancer survivors.
- Trial name
- NCT02465541
- Testing
- Gentle yoga therapy, counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Prostate Carcinoma
Quality of Life and Supportive Care Preferences Following Radiation Therapy in Prostate Cancer Survivors
This pilot clinical trial studies quality of life and supportive care preferences following radiation therapy in prostate cancer survivors.
- Trial name
- NCT02704377
- Testing
- Undergo HRV and wear accelerometer to assess therapy complications, Dual X-ray Absorptiometry, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Fast Food, Fatigue, and Inflammation
This double-blind, randomized crossover trial assessed inflammation and fatigue following a fast-food-type meal (saturated fat) compared to a healthier meal (monounsaturated fat) in breast cancer survivors and benign controls…
- Trial name
- FOOD (NCT04247763)
- Testing
- Saturated Fat Meal, Oleic Sunflower Oil Meal
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking, Cigarette
Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures
The overall aim of the study is to evaluate the provision of e-cigarette (EC) versus NRT on smoking behavior, product use patterns and continued use, and iCO, a biomarker of toxicant exposure, among a sample of recent QL…
- Trial name
- NCT03502200
- Testing
- JUUL, Treatment As Usual
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Clinical Stage IV Cutaneous Melanoma AJCC v8, Pathologic Stage IV Cutaneous Melanoma AJCC v8
The Effect of the Microbiome on Immune Checkpoint Inhibitor Response in Melanoma Patients
This pilot trial studies the effect of the microbiome on immune checkpoint inhibitors response in patients with melanoma by collecting stool and blood samples.
- Trial name
- NCT05102773
- Testing
- Biospecimen Collection, Computed Tomography, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Acute Leukemia, Recurrent Leukemia
Bright White Light Therapy for the Improvement of Sleep, Fatigue, Distress, Depression, and Anxiety in Hospitalized Leukemia Patients
This trial investigates how well bright white light therapy works in improving sleep, fatigue, distress, depression, and anxiety, side effects that are often experienced during an intense leukemia treatment regimen, in…
- Conditions
- Acute Leukemia, Recurrent Leukemia, Refractory Leukemia
- Trial name
- NCT04597086
- Testing
- Best Practice, Bright White Light Therapy, Survey Administration
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cervical Cancer
Community Awareness Resources and Education - Project 1
To increase early detection of cervical cancer by increasing the proportion of Appalachian women, age 18 and older, who receive Pap smears at appropriate intervals and return for follow-up care when necessary.
- Trial name
- CARE (NCT01172561)
- Testing
- Lay Health Advisor Education Intervention, Usual Care Group
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Endometrial Cancer
Lymph Node Mapping in Patients With Endometrial Cancer
This clinical trial studies lymph node mapping in patients with endometrial cancer. Lymph node mapping may allow for limited removal of lymph nodes in as part of endometrial cancer staging and treatment.
- Trial name
- NCT01818739
- Testing
- sentinel lymph node detection, indocyanine green solution, isosulfan blue
- Where
- 2 sites in United States
- Volunteers
- 204 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Carcinoma, Cancer Survivor
Fractional CO2 Laser Therapy for Survivors of Breast Malignancies
This pilot clinical trial studies how well fraction carbon dioxide (CO2) laser therapy works in treating vaginal atrophy in patients with breast cancer.
- Conditions
- Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia
- Trial name
- NCT03307044
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Carcinoma
Stakeholder Assessment of Implementing the Commission on Cancer Operative Standards for Cancer Surgery
This study investigates the barriers to implementing breast Synoptic Operative Reports. Information from this study may help researchers identify performance objectives for the breast Synoptic Operative Reports to be adopted…
- Trial name
- NCT05583981
- Testing
- Interview
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Longitudinal Evaluation of Taxane Induced Neuropathy in Early Stage Breast Cancer
Longitudinal Evaluation of Taxane induced neuropathy in early stage breast cancer.
- Trial name
- NCT02125019
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Recurrent Breast Cancer, Stage IA Breast Cancer
Omega-3 Fatty Acids in Preventing Joint Symptoms in Patients With Stage I-III Breast Cancer Receiving Anastrozole, Exemestane, or Letrozole
This randomized pilot trial studies omega-3 fatty acid in preventing joint symptoms in patients with stage I-III breast cancer receiving anastrozole, exemestane, or letrozole.
- Conditions
- Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT01478477
- Testing
- omega-3 fatty acid supplement, Clinical assessments, Assessment of therapy complications
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Arthralgia, Breast Neoplasms
Omega-3 Supplementation in Prevention of Aromatase Inhibitor-Induced Toxicity in Patients With Stage I-III Breast Cancer
This clinical trial studies the use of omega-3 fatty acid supplementation in preventing aromatase inhibitor-induced toxicity in patients with stage I-III breast cancer.
- Trial name
- NCT02831582
- Testing
- Omega-3 Fatty Acid
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center