Clinical trials: sponsored by Oslo University Hospital
Dorsal Malunion of the Distal Radius
CaP Cement is Equivalent to Iliac Bone Graft in Filling of Large Metaphyseal Defects
CaP Cement is Equivalent to Iliac Bone Graft in Filling of Large Metaphyseal Defects
- Trial name
- NCT02827006
- Testing
- corrective osteotomy distal radius
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ulcerative Colitis, Inflammatory Bowel Diseases
Boosting Biologics in UC
This study evaluates the safety of the probiotic compound IDOFORM TRAVEL® in patients with ulcerative colitis undergoing anti-TNF treatment with insufficient clinical response.
- Trial name
- NCT04241029
- Testing
- IDOFORM®Travel
- Where
- Norway
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Psychotic Disorders, Bipolar Disorder
Honest Open Proud for Psychotic and Bipolar Disorder in Norway
The purpose of this pilot study is to evaluate the feasibility, acceptability and efficacy of a Norwegian adaptation of the group-based intervention 'Honest Open Proud' among adults with psychotic and bipolar disorders in an…
- Conditions
- Psychotic Disorders, Bipolar Disorder, Disclosure
- Trial name
- HOP-NOR (NCT06384755)
- Testing
- Honest Open Proud program
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Essential Hypertension
Effects of Valsartan vs Amlodipine and Low BP on Kidney Outcomes in Essential Hypertension
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial tested the hypothesis that for the same blood-pressure control, valsartan would reduce cardiac morbidity and mortality more than amlodipine in hypertensive…
- Trial name
- VALUE (NCT06395194)
- Testing
- Cardiac outcomes on treatment with valsartan, Cardiac outcomes on treatment with amlodipine
- Volunteers
- 15,313 people
- Sponsor
- Oslo University Hospital
Delirium in Old Age, Delirium of Mixed Origin
Music Therapy as a Treatment for Delirium in Acutely Hospitalized Older Patients
The purpose of this study is to assess feasibility and potential effectiveness of two different music interventions for managing delirium symptoms in acute geriatric patients.
- Conditions
- Delirium in Old Age, Delirium of Mixed Origin, Delirium Superimposed on Dementia, Delirium Confusional State
- Trial name
- NCT05398211
- Testing
- Preferred Recorded Music (PRM), Preferred Live Music (PLM)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital
Delirium, Cognitive Decline
Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
A parallel-group treatment, five-centre, participant and investigator masked, three-arm study to assess the safety and effectiveness of dexmedetomidine or clonidine infusion compared to placebo for the prevention of delirium and…
- Conditions
- Delirium, Cognitive Decline, Frailty
- Trial name
- ALPHA2PREVENT (NCT05029050)
- Testing
- Dexmedetomidine, Clonidine, Natriumchlorid
- Where
- 5 sites in Norway
- Volunteers
- 900 people
- Sponsor
- Oslo University Hospital
Kidney Transplant; Complications, Frailty
Effect of Home-based Training Program for Kidney Transplant Recipients (HOMETRAIN-KTR)
Does home-based training work in kidney transplant recipients with reduced physical function? The goal of this clinical trial is to learn if home-based training works to better physical function in adult kidney transplant…
- Conditions
- Kidney Transplant; Complications, Frailty, Physical Disability
- Trial name
- NCT06379009
- Testing
- Training
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Adenomyosis, Quality of Life
Quality of Life After Hysterectomy (AdenoQOL)
Adenomyosis is a disease where ectopic endometrial-like glands affect the muscular wall of the uterus. About 70% of women affected by adenomyosis suffer from dysmenorrhea and menorrhagia.
- Trial name
- NCT04791033
- Testing
- Hysterectomy
- Where
- Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Trauma Injury, Trauma, Multiple
Effectiveness of a Self-management Program After Traumatic Injury
Traumatic injuries, defined as a physical injury with sudden onset, are a leading cause to disability and impaired health. Persons who sustain a traumatic injury often report problems in daily life activities and reduced quality…
- Conditions
- Trauma Injury, Trauma, Multiple, Polytrauma
- Trial name
- SEMPO (NCT06305819)
- Testing
- self-management support program, Control group
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital
DCIS Grade 3, Stage I Breast Cancer
Energy Balance and Breast Cancer Aspects-II
The purpose of this study, the EBBA-II trial, is to determine whether a 12 month exercise program comprised of strength and endurance training among newly diagnosed breast cancer patients undergoing adjuvant therapy, will…
- Conditions
- DCIS Grade 3, Stage I Breast Cancer, Stage II Breast Cancer, LCIS, Lobular Carcinoma in Situ
- Trial name
- EBBA-II (NCT02240836)
- Testing
- Intervention. Exercise
- Where
- 2 sites in Norway
- Volunteers
- 545 people
- Sponsor
- Oslo University Hospital
Neovascular Age-related Macular Degeneration
Zoledronic Acid as Adjuvant Therapy in Neovascular Age-related Macular Degeneration (Z-AMD)
A pilot study of zoledronic acid as adjuvant therapy to standard anti-vascular endothelial growth factor (anti-VEGF) treatment for neovascular age-related macular degeneration (AMD).
- Trial name
- Z-AMD (NCT04304755)
- Testing
- Zoledronic Acid 5 MG in 5 ML Injection
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Ultrasound for Detection of Prostate Cancer
Clinical proof of concept of dual-frequency ultrasound imaging for detection and visualization of prostate cancer.
- Trial name
- SURF (NCT05736094)
- Testing
- SURF
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Oslo University Hospital
Ischemia, Blood Circulation Disorder
New Method for Real-time Detection of Tissue Ischemia (ISCALERT)
This is a prospective, single arm, open, single centre clinical investigation designed to examine the feasibility and safety of the IscAlert™ device in patients scheduled for limb (arm/leg) surgery with tourniquet.
- Conditions
- Ischemia, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- ISCALERT (NCT04879875)
- Testing
- IscAlert, IscAlert 72h
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Cardiac Arrest, Respiratory Arrest
Norwegian Cardio-Respiratory Arrest Study
The purpose of this study is to evaluate the use of combined clinical-neurological, neurophysiologic, neuroradiological and biochemical markers in prognostication after cardio- and/or respiratory arrest.
- Conditions
- Cardiac Arrest, Respiratory Arrest, Coma
- Trial name
- NORCAST (NCT01239420)
- Where
- Norway
- Volunteers
- 261 people
- Sponsor
- Oslo University Hospital
Substance Use Disorders
From Addiction to Employment.
Patients with substance use disorders have low employment rates and are to a large extent on the outside of the ordinary labor market.
- Trial name
- IPS-SUD (NCT04289415)
- Testing
- Individual Placement and Support
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Kidney Transplant Failure and Rejection
Home Based Monitoring of Kidney Transplants Utilizing Capillary Microsamples
Renal transplant recipients are followed as out patients at the transplant center for about 8 weeks after surgery. Between 1-2 weeks after surgery, 50 standard immunological patients will be randomized (1:1) to either follow…
- Trial name
- HBM-KTx (NCT04369612)
- Testing
- Standard follow-up, Home-based monitoring
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Kidney Transplant; Complications, Immune Suppression
Immunosuppressive Drugs and Gut Microbiome: Pharmacokinetic- and Microbiome Diversity Effects
Kidney transplant recipients of living- and deceased donor grafts and treated with both mycophenolate mofetil (MMF) and tacrolimus (Tac) will be included.
- Trial name
- MicrobioTac (NCT04207177)
- Testing
- Mycophenolate Mofetil 500 mg Tab, Tacrolimus capsule
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Labor Complication, Induced; Birth
SAINT: Safe Induction of Labor Trial
Over the past years, the rates of labor induction have increased steadily, and at present more than one in four births occurs after induced labor in Norway.
- Conditions
- Labor Complication, Induced; Birth, Pregnancy Related
- Trial name
- SAINT (NCT05719467)
- Testing
- Buscopan 20 MG/ML Injectable Solution, Sodium bicarbonate, Nacl 0.9%
- Where
- 5 sites in Norway
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Glioblastoma
Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy
Open, randomized study of a trivalent dendritic cell therapy compared to standard therapy in primary treated patients with IDH wild-type, MGMT-promotor methylated glioblastoma.
- Trial name
- DEN-STEM (NCT03548571)
- Testing
- Dendritic cell immunization, Adjuvant temozolomide
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Penile Cancer
The Role of Functional Magnetic Resonance Imaging in Preoperative Assessment of Primary Penile Carcinoma
The proposed project is intended as a prospective study that includes 60 patients with newly diagnosed penile squamous cell carcinoma (SCC) referred to Oslo University Hospital (OUH), Radiumhospitalet, for surgery, primarily…
- Trial name
- NCT05447273
- Testing
- Multi-parametric, functional magnetic resonance imaging (MRI)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital