Clinical trials: sponsored by Oslo University Hospital
Cancer Screening
Increasing Access to Breast Cancer Screening Among Immigrants
The investigators aim to test whether inviting immigrants to breast cancer screening with a letter in their mother tongue in addition to the standard letter in Norwegian changes screening uptake in these immigrant groups…
- Trial name
- NCT04672265
- Testing
- Mother tongue and Norwegian
- Where
- Norway
- Volunteers
- 11,355 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiac Arrest, Out-Of-Hospital, Hypotension and Shock
BCG Biosensor and Non- and Invasive Monitoring During Emergency Medicine Cases, a Prospective Feasibility Study
In a out of hospital emergency medicine study the investigators will measure hemodynamic effects of implemented treatments for patients with cardiac arrest, hypotension, and intensive care transports.
- Trial name
- NCT04891380
- Testing
- LUCAS 2 Active Decompression 2, Hypotension, Intensive care transport
- Where
- Norway
- Volunteers
- 183 people
- Sponsor
- Oslo University Hospital
Recurrent Glioblastoma
Individualized Systems Medicine Functional Profiling for Recurrent Glioblastoma
A study to determine the feasibility and safety of individualized cancer stem cell targeted therapy based on high-throughput functional profiling of FDA/EMA-approved drugs in patients with GBM that has recurred or progressed…
- Trial name
- ISM-GBM (NCT05043701)
- Testing
- Personalized drug combination
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Locally Advanced Pelvic Cancer That Require Pelvic Exenteration
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers
The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic…
- Trial name
- NCT05186493
- Testing
- robot-assisted total pelvic exenteration
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Penile Cancer
The Role of Functional Magnetic Resonance Imaging in Preoperative Assessment of Primary Penile Carcinoma
The proposed project is intended as a prospective study that includes 60 patients with newly diagnosed penile squamous cell carcinoma (SCC) referred to Oslo University Hospital (OUH), Radiumhospitalet, for surgery, primarily…
- Trial name
- NCT05447273
- Testing
- Multi-parametric, functional magnetic resonance imaging (MRI)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Nerve Block, Cleft Palate
Maxillary Nerve Blocks in Children - An MRI Study of the Suprazygomatic Approach
Ultrasound-guided suprazygomatic maxillary nerve block (SMNB) will be performed in paediatric patients with or without the aid of ultrasound guidance.
- Conditions
- Nerve Block, Cleft Palate, Analgesia
- Trial name
- NCT05778903
- Testing
- Nerve block
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Cognitive Dysfunction, Dementia
Intelligent Digital Tools for Screening of Brain Connectivity and Dementia Risk Estimation in People Affected by Mild Cognitive Impairment
Every three seconds someone in the world develops dementia. There are over 50 million people worldwide living with dementia and by 2030 this figure is expected to reach 82 million.
- Conditions
- Cognitive Dysfunction, Dementia, Mild Cognitive Impairment
- Trial name
- AI-Mind (NCT05159661)
- Where
- 5 sites in Finland, Italy and 2 more
- Volunteers
- 1,000 people
- Sponsor
- Oslo University Hospital
Delirium
Analyses of Cerebrospinalfluid in Patients With Delirium
The current project aims to measure biomarkers in the cerebrospinalfluid (CSF) and serum samples from patients with delirium. We hope to uncover new insights into the pathophysiology of delirium and explore its link to dementia.
- Trial name
- NCT05060614
- Testing
- Hip fracture surgery
- Where
- Norway
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Low Back Pain
BackToBasic: Infliximab in Chronic Low Back Pain and Modic Changes
Low-Back Pain (LBP) is the leading cause of disability worldwide. Even though LBP relates to different underlying pathologies, there are a substantial number of patients with chronic complaints that have vertebral bone marrow…
- Trial name
- NCT03704363
- Testing
- Biosimilar Infliximab
- Where
- 6 sites in Norway
- Volunteers
- 128 people
- Sponsor
- Oslo University Hospital
Trichotillomania
Cognitive Behavioral Group Therapy for Trichotillomania (Hair Pulling Disorder)
This study aims at evaluating the effectiveness of group-based cognitive behavioral therapy for trichotillomania at three clinical sites in Norway.
- Trial name
- NorTriP (NCT02747771)
- Testing
- Cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
Lateral Epicondylitis, Tennis Elbow
The NOrwegian Tennis Elbow (NOTE) Study
Trial Design: The Norwegian Tennis Elbow (NOTE) study is a single-centre; three-armed, feasibility randomised controlled trial. Aim: The primary aim of this study is to pilot the methods proposed to conduct a definite RCT study.
- Conditions
- Lateral Epicondylitis, Tennis Elbow, Tendinopathy, Elbow
- Trial name
- NCT04803825
- Testing
- Heavy Slow Exercises, Extracorporeal Shock wave therapy, Information and advice
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Cancer, Non Small Cell Lung Cancer
Durvalumab(MEDI4736) After chemoRadioTherapy(DART) for NSCLC-a Translational and Biomarker Study
The main aim is to identify and describe biomarkers in different sample types related to chemoradiation followed by durvalumab treatment for stage III PD-L1 negative and positive non-small cell lung cancer (NSCLC) patients'…
- Conditions
- Cancer, Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Stage III, NSCLC
- Trial name
- DART (NCT04392505)
- Testing
- Durvalumab Injection
- Where
- 10 sites in Estonia, Finland and 2 more
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Cancer Metastatic
Improving Public Cancer Care by Implementing Precision Medicine in Norway
IMPRESS-Norway is a prospective, non-randomized clinical trial evaluating efficacy of commercially available, anti-cancer drugs prescribed for patients with advanced cancer diagnosed with potentially actionable alterations as…
- Trial name
- IMPRESS-N (NCT04817956)
- Testing
- Atezolizumab
- Where
- 17 sites in Norway
- Volunteers
- 3,000 people
- Sponsor
- Oslo University Hospital
Non-rheumatoid Wrist Arthritis
Motec Versus Remotion Total Wrist Arthroplasty - A Prospective Study
The purpose of this study is to determine the difference in the results between Motec and Remotion wrist arthroplasty in the treatment of non-rheumatoid wrist arthritis.
- Trial name
- NCT01842724
- Testing
- Motec total wrist arthroplasty, Remotion total wrist arthroplasty
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Anesthesia, Vascular Access Complication
Echogenic Versus Non-echogenic Needles for Venous Access
Randomized controlled intervention study comparing echogenic needles with non echogenic needles for ultrasound guided venous access in the subclavian vein.
- Trial name
- NCT05045352
- Testing
- echogenic needles for intravenous access
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Distal Radius Fractures, Wrist Fracture
Unstable Distal Radius Fractures With Dorsal Dislocation in Patients Aged 18-64 Years. Volar Locking Plate (VLP) vs Closed Reduction and Percutaenous Pinning (CRPP).
120 patients age 18-64 years with dorsally displaced distal radius fractures AO-type A2, A3 and C1 are recruited from Oslo Casualty Medical Centre (Oslo Skadelegevakt).
- Conditions
- Distal Radius Fractures, Wrist Fracture, Colles' Fracture
- Trial name
- NCT04716309
- Testing
- Open reduction and volar locking plate and closed reduction and K-wires.
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Keratoconus
Simultaneous pHototherapeutic Keratectomy and corneAl Collagen cRosslinking in Eyes With Keratoconus: a Randomized Trial (SHARK)
The goal of this clinical trial is to compare CXL with combined treatment with CXL and t-PTK. The main questions it aims to answer are whether combined treatment can give better visual acuity and if the treatments are equally…
- Trial name
- NCT06264024
- Testing
- Corneal collagen cross linking (CXL), Transepithelial phototherapeutic keratectomy (t-PTK)
- Where
- Norway
- Volunteers
- 81 people
- Sponsor
- Oslo University Hospital
Aortic Stenosis, Anxiety
10-year Follow-up After Aortic Valve Replacement Surgery
There is a lack of data on patients self-reported outcomes (PROMs) on health-related quality of life (HRQoL)and symptoms on anxiety and depression 10 years after Surgical After Aortic Valve Replacement (SAVR), and patient…
- Conditions
- Aortic Stenosis, Anxiety, Depressive Symptoms, Quality of Life
- Trial name
- AVR-10year (NCT06255691)
- Volunteers
- 282 people
- Sponsor
- Oslo University Hospital
Colorectal Cancer, Liver Metastasis
Liver Transplantation and Colorectal Cancer
Colorectal liver metastases (CLM) are currently considered an absolute contraindication for liver transplantation (Lt) although Lt for other primary and secondary liver malignancies show excellent outcome in selected patients.
- Trial name
- NCT01479608
- Testing
- Liver transplantation and liver resection
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Oslo University Hospital
Colorectal Cancer
Partial Liver Segment 2/3 Transplantation Study
The patients will receive hepatectomy as a 2 stage procedure. In the first surgical procedure liver segments 2-3 are removed and liver donor segments 2-3 inserted.
- Trial name
- NCT02215889
- Testing
- Liver transplantation
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital