Clinical trials: sponsored by Oslo University Hospital
Lisfranc Injuries
Arthrodesis Versus Extra-articular Plate Fixation in Lisfranc Injury
The purpose of this study is to compare arthrodesis of the first TMT-joint to extraarticular bridge plate fixation of the same joint in acute Lisfranc injuries.
- Trial name
- NCT01448941
- Testing
- Temporary extraarticular plate fixation, Primary arthrodesis, Primary arthrodesis TMT 2 and 3
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- Oslo University Hospital
Adenomyosis, Infertility
Norwegian Adenomyosis Study III: Peristalsis
Spontaneous contractions (peristalsis) of the non-pregnant uterus is widely investigated and the role of correct peristalsis is most important for correct sperm transport towards the fallopian tubes and implantation of the…
- Conditions
- Adenomyosis, Infertility, Dysmenorrhea
- Trial name
- NAPPEDIII (NCT02197936)
- Where
- Norway
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Wound (Morphologic Abnormality)
Hyperbaric Oxygen Treatment as Adjuvant Treatment for Frost Injury
The aim of this study is to see weather hyperbaric oxygen treatment is beneficial as adjuvant treatment for frost damage. The investigators hope to include at least 20 patients in a randomized manner.
- Trial name
- FROST (NCT01270477)
- Testing
- Hyperbaric oxygen treatment
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Coronary Disease, Myocardial Infarction
ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial
The main goal of this study is to evaluate the ability of a single administration of tocilizumab to reduce myocardial damage in patients presenting with an acute ST-segment elevation myocardial infarction (STEMI).
- Trial name
- ASSAIL-MI (NCT03004703)
- Testing
- Tocilizumab, Sodium chloride 0.9%
- Where
- 3 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Atopic Dermatitis
Atopic Dermatitis: Early Gene Expression Changes as Predictors of Therapeutic Response to Narrow-band UVB Treatment
Phototherapy with narrow band (nb) ultraviolet B (UVB) is a safe and effective but time consuming treatment option for patients with widespread eczema.
- Trial name
- NCT03402412
- Testing
- narrow-band UVB
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Oslo University Hospital
Obesity
Naltrexone/Bupropion (Mysimba) to Optimize Weight Outcomes After Obesity Surgery
Limited/poor weight loss and weight regain are concerns following bariatric surgery, and weight regain may increase the risk for relapse of comorbidities related to obesity.
- Trial name
- NCT04399395
- Testing
- Naltrexone/bupropion, Lifestyle
- Sponsor
- Oslo University Hospital
Hypothermia
Preventing Inadvertent Hypothermia in Paediatric Neurosurgery in Malawi
The investigators wish to undertake a randomized controlled non-inferiority trial to evaluate the ability of a simple and low-cost method (Hibler´s method of wrapping the patient in multiple insulating layers) to prevent…
- Trial name
- NCT02975817
- Testing
- Hibler's, Warm Air
- Where
- Malawi
- Volunteers
- 76 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Prostate Cancer in Firemen: Early Diagnosis Because of Increased Diagnostic Pressure?
Firefighters, police, military personnel and pilots are all shown to have a higher incidence of prostate cancer than the general population.
- Trial name
- NCT03896178
- Testing
- None, observational study
- Where
- Norway
- Volunteers
- 137,536 people
- Sponsor
- Oslo University Hospital
Follicular Lymphoma
Sequential Intranodal Immunotherapy (SIIT) Combined With Anti-PD1 (Pembrolizumab) in Follicular Lymphoma
Follicular lymphoma (FL) is the most common subtype of indolent non-Hodgkin's lymphoma and is often diagnosed in advanced incurable stage.
- Trial name
- Lymvac-2 (NCT02677155)
- Testing
- Radiotherapy, Rituximab, Autologous dendritic cells
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Coronary Heart Disease
Adipose Tissue and Inflammation in Coronary Heart Disease
The aims of the present project are to study possible differences in inflammatory gene expression and protein secretion in various compartments of adipose tissue being exposed during open cardiac surgery in patients with coronary…
- Trial name
- ATICH (NCT02760914)
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Leg Length Inequality, Leg; Lengthening
Femoral Lengthening Might Impair Physical Function and Lead to Structural Changes in Adjacent Joints
This study evaluates function, quality of life and development of hip- and knee osteoarthritis minimum 15 years after unilateral femoral lengthening on people with idiopathic or post-traumatic anisomelia.
- Conditions
- Leg Length Inequality, Leg; Lengthening, Osteoarthritis, Knee, Osteoarthritis of Hip
- Trial name
- NCT03966573
- Testing
- Radiographic imaging, Evaluating function, Forms
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Anesthesia
Expired Propofol in Low Back Surgery
Edmon (BBraun, Germany) is a portable, commercially available device for measurement of propofol in exhaled air. The study will aim at evaluating the sensitivity and specificity of such exhaled propofol values compared with…
- Trial name
- NCT04771702
- Testing
- Edmon
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney
Lowering Uric Acid in Live Kidney Donors
Recently there was described an increase in left ventricular mass after kidney donation. It is uncertain whether this is reversible or not.
- Trial name
- AL-DON (NCT03353298)
- Testing
- Allopurinol 300 mg
- Where
- Norway
- Volunteers
- 71 people
- Sponsor
- Oslo University Hospital
Hereditary Motor and Sensory Neuropathy, Charcot-Marie-Tooth
Physical Activity in Persons With Charcot-Marie-Tooth: Developing a Measurement Instrument
The project will develop knowledge about physical activity in persons with Charcot-Marie-Tooth (CMT) in Norway. We plan to explore instruments to measure physical activity level for the target-group at the community level.
- Conditions
- Hereditary Motor and Sensory Neuropathy, Charcot-Marie-Tooth, Polyneuropathies
- Trial name
- NCT04461613
- Testing
- Original IPAQ followed by a revised one., Revised IPAQ followed by an original one.
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Anorectal Malformations, Transition
Transition of Care for Patients With Hirschsprung Disease and Anorectal Malformations
Transition from paediatric to adult health care is crucial for preventing deterioration of chronic diseases. At present, transitional care (TC) is not established for patients with the Hirschsprung disease (H) and Anorectal…
- Conditions
- Anorectal Malformations, Transition, Quality of Life, Hirschsprung Disease
- Trial name
- NOHARM (NCT04106947)
- Testing
- Questionnaires
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Oslo University Hospital
Pregnancy Complications, Placental Insufficiency
PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome
The PREPPeD study proposes that predelivery placenta-derived maternal circulating biomarkers reflect placental health, capacity and ageing, and can help predict onset and complications of delivery both in complicated pregnancies…
- Trial name
- PREPPeD (NCT03100084)
- Testing
- Blood sampling
- Where
- Norway
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cervical Intraepithelial Neoplasia, Cervical Cancer
Impact of HPV Vaccine On The Prevalence Of HPV In Norway
The overall aim of the study is to assess the effect of school-based Human Papillomavirus (HPV) vaccination by comparing type-specific HPV prevalence between vaccinated and non-vaccinated women born in 1997.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Oropharyngeal Cancer
- Trial name
- NCT02934724
- Testing
- Self sample from vagina, Self sample from the oral cavity, Questionnaire
- Where
- Norway
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hemophilia A Without Inhibitor
HemFitBit, an Observational Study of Physical Activity in People With Moderate and Severe Haemophilia A
The study aims to describe physical activity (PA) levels in young people with haemophilia A in Norway compared with non-haemophilia controls, and to identify factors influencing PA.
- Trial name
- NCT04181697
- Testing
- PA measurement with Fitbit Charge 3, PA measurement with Fitbit and ActiGraph GT3X
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Abdominal Pain, Quality of Life
Abdominal Pain and Symptoms Post Gastric Sleeve
Exploration of abdominal pain post sleeve gastrectomy in morbid obese patients
- Trial name
- NCT03456024
- Testing
- Questinnaire
- Where
- Norway
- Volunteers
- 250 people
- Sponsor
- Oslo University Hospital
Traumatic Brain Injury
Family Centered Intervention After Traumatic Brain Injury
The purpose of this study is to determine the effectiveness of a multi-professional theoretically based family centered intervention, The Traumatic Brain Injury Family System Intervention (TBIFSI), for the family members and TBI…
- Trial name
- NCT03000400
- Testing
- The Traumatic Brain Injury Family System Intervention., Psycho-educational session at OUH
- Where
- Norway
- Volunteers
- 136 people
- Sponsor
- Oslo University Hospital