Clinical trials: sponsored by Oslo University Hospital
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Intraocular Lens Dislocation
Late Dislocation of Intraocular Lens (IOL) Following Cataract Surgery: an Evaluation of Two Different Surgical Methods
A prospective randomized study on patients with late in the bag intraocular lens (IOL) dislocation, after cataract surgery. To obtain normal visual function, these patients needs surgery.
- Trial name
- NCT01784926
- Testing
- Intraocular lens repositioning by scleral suturing, Intraocular lens exchange with retropupillary iris-claw lens
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Oslo University Hospital
Stress Fracture Foot, Stress Fracture Ankle
Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial
The effect of an intravenous bisphosphonate (zoledronic acid) on healing and symptoms of stress fractures that do not respond to conservative/conventional treatment within 6 months, will be investigated.
- Trial name
- NCT03576599
- Testing
- Zoledronic Acid Injectable Product
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Neuromuscular Diseases, Children, Only
Mechanical Cough Augmentation in Children With NMD
The study investigates the prevalence and use of mechanical insufflation - exsufflation (MI-E) in children with Neuromuscular disorders (NMD) in Norway.
- Conditions
- Neuromuscular Diseases, Children, Only, Airway Clearance Impairment, Cough
- Trial name
- NCT03831568
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- Oslo University Hospital
Myocardial Infarction, Angina
Prospective Randomized Optical Coherence Tomography Oslo tRial
Coronary artery intervention with stents is a routine procedure with several clinical indications. A stentfailure, ie stentrestenosis and/or stentthrombosis will occur in some patients.
- Trial name
- PROCTOR (NCT02337348)
- Testing
- Optical coherence tomography, Coronary angiography
- Where
- Norway
- Volunteers
- 163 people
- Sponsor
- Oslo University Hospital
Atopic Dermatitis, Food Allergy in Children
Preventing Atopic Dermatitis and ALLergies in Children
The primary objective is of the PreventADALL study is to test if primary prevention of allergic diseases is possible by simple and low cost strategies, and secondary to asses the impact of xenobiotic exposure and microbiota in…
- Conditions
- Atopic Dermatitis, Food Allergy in Children, Asthma, Rhinitis, Allergic
- Trial name
- PreventADALL (NCT02449850)
- Testing
- Food intervention, Skin care
- Where
- Norway
- Volunteers
- 2,701 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Heart Failure, Systolic
Pharmacodynamic Effects of Sacubitril/Valsartan on Natriuretic Peptides, Angiotensin and Neprilysin
The study measure multiple neurohormones in patients with heart failure being treated with Sacubitril/Valsartan in increasing doses over an 8 week period.
- Trial name
- NCT03553303
- Testing
- Sacubitril / Valsartan Oral Tablet
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Renal Transplant Rejection
Dose Adjustment of Tacrolimus Based on Home Sampling in Renal Transplant Recipients
Repeated 12-hour pharmacokinetic (PK) investigations in renal transplant recipients for parallel sampling of standard venous bloods samples and finger prick micro samples (Mitra tips).
- Trial name
- TacDrop (NCT03512431)
- Testing
- Micro sampling
- Where
- Norway
- Volunteers
- 27 people
- Sponsor
- Oslo University Hospital
Hypertension
Treatment of Hypertension: an Interventional Approach to Improve Blood Pressure Control
The purpose of the study is to access the change in mean daytime systolic blood pressure in participants with essential hypertension not adequately controlled (defined as mean systolic daytime ambulatory blood pressure ≥ 135…
- Trial name
- DRIVE (NCT02362893)
- Testing
- Direct Observed Therapy
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Lifestyle, Diet Habit
Tailored Written Lifestyle Feedback in Colorectal Cancer Screening
This randomized controlled trial aims to investigate the effect of an individually tailored lifestyle feedback letter and a leaflet on lifestyle in the context of sigmoidoscopy screening.
- Conditions
- Lifestyle, Diet Habit, Smoking Cessation, Physical Activity
- Trial name
- NCT03396029
- Testing
- Individually tailored lifestyle feedback, Standard leaflet
- Volunteers
- 3,642 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Congenital Heart Disease
Fontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term Effects
Cross-sectional study of a national cohort of adolescents with univentricular congenital heart defects and Fontan type palliation.
- Trial name
- NCT02378857
- Where
- Norway
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Malnutrition
Development of a Decision Support System to Prevent and Treat Disease-related Malnutrition
The prevalence of disease-related malnutrition among hospitalized patients is 30-50%. There is a lack of tools to follow up the nutritional treatment of these patients.
- Trial name
- NCT03412695
- Testing
- MyFood
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Carotid Artery Stenoses
Pre- and Post-operative Brain MRI in Carotid Endarterectomy
Patients undergoing carotid endarterectomy in the Department of Vascular Surgery at Oslo University Hospital are consecutively included in this evaluation og pre- and postoperative brain MRI.
- Trial name
- NCT04029259
- Testing
- Brain MRI
- Volunteers
- 320 people
- Sponsor
- Oslo University Hospital
Colorectal Cancer
T Cell Receptor Based Therapy of Metastatic Colorectal Cancer
T Cell Receptor Based Therapy of Metastatic Colorectal Cancer With mRNA-engineered T Cells Targeting Transforming Growth Factor Beta Receptor Type II (TGFβII)
- Trial name
- TCR-CRC-001 (NCT03431311)
- Testing
- Adoptive Cell Therapy (ACT)
- Where
- Norway
- Volunteers
- 1 people
- Sponsor
- Oslo University Hospital
Maternal Behavior
Midwife-led Continuity and Satisfaction With Care - an Observational Case-Control Study in Palestine
This study investigate if a midwife-led continuity model of care in Palestine, had impact on rural women's satisfaction with care through the continuum of antenatal, intrapartum and postnatal period.
- Trial name
- NCT03863600
- Testing
- Midwife-led continuity of care
- Where
- Palestinian Territories
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Myeloma, Multiple, PET-CT
Fluciclovine PET/CT in Multiple Myeloma Patients
Comparison between image findings at aminoacid PET/CT and FDG PET/CT for myeloma patients
- Trial name
- FLUCIPET (NCT03966443)
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Heart Defects, Congenital
Livet Skal Leves (A Life to Live)
The overall objective of this project is to optimize the use of diagnostic methods and follow-up programs in infants with congenital heart defects (CHDs) in order to reduce death and complications
- Trial name
- NCT03957512
- Testing
- Heart surgery
- Where
- Norway
- Volunteers
- 3,000 people
- Sponsor
- Oslo University Hospital
Esophageal Neoplasm
Palliation Dysphagia Cancer Oesophagus Stent+Brachytherapy Versus Brachytherapy Only
We wish to improve the swallowing function of patients with advanced cancer of the oesophagus, by carrying out a randomised clinical study in which we compare primary stenting followed by brachytherapy in the stent, 8 G x 3 with…
- Trial name
- PACO (NCT00653107)
- Testing
- Stent insertion, Brachytherapy
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Oslo University Hospital
Attention Deficit Hyperactivity Disorder, Disruptive Mood Dysregulation Disorder
Children With ADHD and Emotional Dysregulation
Studies have shown that children with Attention Deficit Hyperactivity Disorder (ADHD) and emotional dysregulation are characterized by high severity of ADHD, comorbid behavior disorders and increased risk of chronic difficulties.
- Trial name
- MOODY (NCT03944083)
- Testing
- Treatment as usual for ADHD
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Pancreas Transplantation
The Norwegian Pancreas Transplantation (PTx) Study
Several studies have shown acceptable results after Pancreas Transplantation (PTx) by substituting ATG with basiliximab, which is considered to convey a considerably lower number of adverse events.
- Conditions
- Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec
- Trial name
- PTx (NCT01957696)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital