Clinical trials: sponsored by Oslo University Hospital
Intraocular Lens Dislocation
Late In-the-bag intraOcular Lens dislocatioN Surgery
Overall aim of the study is to compare the safety and efficacy of two different surgical methods to treat Late In-the-bag intraocular lens dislocation.
- Trial name
- LION (NCT03276104)
- Testing
- IOL repositioning, IOL exchange
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Postthrombotic Syndrome
Prevalence of Post-Thrombotic Syndrome in Deep-Vein Thrombosis (DVT) Patients Treated With Dabigatran
The primary objective in this cross-sectional study is to assess the prevalence of post-thrombotic syndrome (PTS) in the two treatment arms of the RE-COVER studies (warfarin versus dabigatran).
- Trial name
- DABI-PTS (NCT03050138)
- Where
- 3 sites in Canada, Norway and 1 more
- Volunteers
- 351 people
- Sponsor
- Oslo University Hospital
Pain, Postoperative, Pain Uterus
Effects of Tapentadol Versus Oxycodone After Hysterectomy.
Opioids remain the first-line drugs for the treatment of moderate to severe postoperative pain, but the use is limited by well-known side-effects, most of which are dose-dependent.
- Conditions
- Pain, Postoperative, Pain Uterus, Pain, Acute, Opioid Use
- Trial name
- NCT03314792
- Testing
- Tapentadol, Oxycodone
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital
Systolic Heart Failure
GutHeart: Targeting Gut Microbiota to Treat Heart Failure
The objective of this trial is to study the effect of targeting the gut microbiota in patients with heart failure (HF). First, the investigators will characterize gut microbiota composition in patients with various degree of…
- Trial name
- NCT02637167
- Testing
- Rifaximin, Saccharomyces boulardii
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
Induced; Birth, Delivery Complication
The Norwegian Induction Project: a Pilot for a Prospective National Audit
The worldwide rate of induction of labour has been steadily increasing over the last 15 years, a trend that is reflected in Norway.
- Conditions
- Induced; Birth, Delivery Complication, Indications for Care in Pregnancy; Labor; and Delivery
- Trial name
- NCT03730220
- Where
- Norway
- Volunteers
- 1,846 people
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Renal Insufficiency
Empagliflozin in Renal Transplant Recipients
This is a single-center, prospective, controlled, double-blind, randomized study. A total of 50 renal transplant recipients diagnosed with post-transplantation diabetes mellitus (PTDM) will be included more than 1 year after…
- Conditions
- Diabetes Mellitus, Renal Insufficiency, Safety Issues
- Trial name
- EMPA-RenalTx (NCT03157414)
- Testing
- Empagliflozin
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- Oslo University Hospital
Brain Tumor
Follow-up Survey of Patients Who Were Treated for Medulloblastoma or Primitive Neuroectodermal Tumors of the Central Nervous in Norway
Clinical follow-up survey of the Norwegian material of paediatric patients who received therapy for medulloblastoma and CNS-PNET from 1974 - 2013 with a focus on quality of life, education, work, family and children, delayed…
- Trial name
- NCT02851355
- Where
- Norway
- Volunteers
- 2 people
- Sponsor
- Oslo University Hospital
Non-ST Elevation Myocardial Infarction, Acute Coronary Syndrome
One-hour Troponin in a Low-prevalence Population of Acute Coronary Syndrome
This study aims to evaluate if the 1-hour rule-in/rule-out algorithm for a high-sensitivity cardiac troponin T (hs-cTnT) is safe and effective for use in the primary care where the patients have a lower pretest probability of an…
- Conditions
- Non-ST Elevation Myocardial Infarction, Acute Coronary Syndrome, Angina, Unstable, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- OUT-ACS (NCT02983123)
- Testing
- 1-hour hs-cTnT
- Where
- Norway
- Volunteers
- 1,750 people
- Sponsor
- Oslo University Hospital
Metastatic Cancer
N-of-1 Trial: Actionable Target Identification in Metastatic Cancer for Palliative Systemic Therapy
The metastatic lesions may be very different from the primary tumor because of intrinsic tumor heterogenity, clonal selection through metastatic process and following previous cytotoxic treatments.
- Trial name
- MetAction (NCT02142036)
- Testing
- EMA-approved ATI based targeted therapy
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Scleroderma, Systemic
Gut Microbiota Transplantation in Systemic Sclerosis
Systemic Sclerosis (SSc) is a progressive multi-organ disorder with high disease burden. Life expectancy in SSc is reduced by 25-40 years, mainly due to cardiopulmonary and gastro-intestinal (GI) disease involvement; and a very…
- Trial name
- ReSScue (NCT03444220)
- Testing
- Anaerobically Cultivated Human Intestinal Microbiota, Anaerobically Cultivated medium
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Cancer
Whole Brain Radiation With or Without Erlotinib for Brain Metastases From Non-Small Cell Lung Cancer
To determine if erlotinib given orally along with concurrent whole brain irradiation in lung cancer patients with brain metastases improves median overall survival and enhances local control compared to those treated with WBRT…
- Trial name
- RadEr (NCT01518621)
- Testing
- Radiation, Radiation plus erlotinib
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Oslo University Hospital
Prenatal Care
Validation of a Midwifery Model in Palestine 2
A midwife-led continuity model of care was implemented in governmental maternal facilities in Palestine. Midwives from the hospitals provided outreaching caseload ante- and postnatal care to women in rural villages clinics and…
- Trial name
- NCT03640663
- Testing
- Midwife led continuity model of care
- Where
- Palestinian Territories
- Volunteers
- 2,199 people
- Sponsor
- Oslo University Hospital
Tonsillar Hypertrophy, Tonsillitis
Comparison of Bizact With Electroscissor for Tonsillectomy
In a randomized, partly double-blind prospective setup we want to compare traditional adult electro-scissor tonsillectomy With ultrasound Technology, Bizact.
- Trial name
- NCT03854279
- Testing
- tonsillar dissection
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Urinary Incontinence, Urinary Stress Incontinence
Pregnancy After Tension-free Vaginal Tape and Other Mid-urethral Sling Procedures
The purpose of this study is to determine the interactions between pregnancy and urinary stress incontinence in women with a mid-urethral sling (MUS).
- Conditions
- Urinary Incontinence, Urinary Stress Incontinence, Pregnancy Complications
- Trial name
- PregnanT (NCT02999347)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Lung Cancer
Fitness, Activity and Lung Cancer Study
The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection.
- Trial name
- FALC (NCT01748981)
- Testing
- Physical training, As usual
- Where
- Norway
- Volunteers
- 71 people
- Sponsor
- Oslo University Hospital
Bariatric Surgery Candidate, Cholecystectomy
Expiratory and Plasma Propofol Concentration in Gastrological Surgery Patients
Determination of accuracy With Edmond (reg) expiratory propofol measurement Device, compared With concommitant plasma samples of propofol
- Trial name
- NCT03817541
- Testing
- Edmon (reg), BBraun
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo University Hospital
Chronic Pain, Impaired Pupillary Reflex
Pupil Response in Patients on Opioids.
Evaluation of pupillary reflex in patients on high-dose opioids. Clinical assessment of pain intensity, sedation score, and other side effects of opioids.
- Conditions
- Chronic Pain, Impaired Pupillary Reflex, Opioid-Related Disorders
- Trial name
- Pupillometry (NCT02247024)
- Where
- 2 sites in Norway
- Volunteers
- 63 people
- Sponsor
- Oslo University Hospital
Subacromial Pain Syndrome
Exercise for Subacromial Pain Syndrome
This study evaluates the effect of Heavy Slow Resistance exercise (HSR) exercise in comparison with traditional supervised exercise as treatment for patients with subacromial shoulder pain.
- Trial name
- NCT03317808
- Testing
- Different exercise
- Where
- Norway
- Volunteers
- 22 people
- Sponsor
- Oslo University Hospital
Post Traumatic Stress Symptoms, Post ICU Patient
Follow up After Intensive Care. The FUTstudy
To investigate the effect of nurse led follow up talks to prevent posttraumatic stress (PTS) symptoms and improve quality of life and sence of coherence after an intensive care unit (ICU) stay.
- Trial name
- FUT (NCT02077244)
- Testing
- Follow up talks
- Where
- Norway
- Volunteers
- 224 people
- Sponsor
- Oslo University Hospital
Nerve Block
Intelligent Needle Tip Tracking Using Ultrasound Imaging for Lumbar Plexus Blocks
In a randomized controlled crossover study design, ultrasound guided lumbar plexus blocks will be performed with and without the aid of a needle tip tracking (NTT) system.
- Trial name
- NCT03667898
- Testing
- Lumbar plexus block using NTT, Lumbar plexus block without NTT
- Where
- Norway
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital