Clinical trials: sponsored by Oslo University Hospital
Diabetes, Type I, Enterovirus Infections
Diabetes Virus Detection Project, Intervention With GAD-alum
The purposes of this study are to test whether GAD vaccination can stop the progression of newly diagnosed type 1 diabetes, to describe the related immunological processes (insulitis) in pancreas and small intestines evolving the…
- Conditions
- Diabetes, Type I, Enterovirus Infections, Autoimmunity
- Trial name
- DiViD (NCT01129232)
- Testing
- GAD-alum
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Oslo University Hospital
Schizophrenia, Bipolar Disorder
Using Motivational Techniques to Increase Levels of Physical Activity in Long Term Psychiatric Inpatient Wards
The current research project aims at investigating whether it is possible to obtain an increase in physical activity among inpatients with schizophrenia spectrum disorders by the use of motivational interviewing and environmental…
- Conditions
- Schizophrenia, Bipolar Disorder, Inpatient Facility Diagnoses, Cardiovascular Risk Factor
- Trial name
- FYSAKT (NCT03528278)
- Testing
- Motivational interviewing and environmental interventions
- Where
- 2 sites in Norway
- Volunteers
- 83 people
- Sponsor
- Oslo University Hospital
Flaccid Hemiplegia, Flaccid Paraplegia
European Paediatric AFM Associated With EV-D68 Follow-up Study.
The study is a follow-up study on children with acute flaccid paresis associated with enterovirus D68 infection. Only children living in Europe are eligible.
- Conditions
- Flaccid Hemiplegia, Flaccid Paraplegia, Flaccid Tetraplegia, Unspecified, Enterovirus D68
- Trial name
- NCT03499366
- Testing
- HFMS, MRC, ACTIVLIM, PedsQl-4.0
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Traumatic Brain Injury, Brain Concussion
Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury
The main aim of this study is to evaluate the effect of vestibular rehabilitation and balance training on patients with dizziness and balance problems after traumatic brain injury.
- Conditions
- Traumatic Brain Injury, Brain Concussion, Head Injury, Dizziness
- Trial name
- VRTBI2012 (NCT01695577)
- Testing
- Multidisciplinary evaluation and VR, Multidisciplinary evaluation
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Oslo University Hospital
Heart Defects, Congenital
Colloid Osmotic Pressure in Patients With Fontan Circulation
Children born with univentricular heart will go through step surgery and end up with a Fontan circulation. A circulation with cause problems with body fluid balance.This project will evaluate changes in interstitial colloid…
- Trial name
- NCT02443662
- Testing
- Catheterization
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
Changes in Cardiac Output
Non-invasive Evaluation of Volume Status Using Exhaled Carbon Dioxide and Pulse Contour Analysis
The investigators hypothesize that changes in blood circulation can be reflected by exhaled CO2 provided CO2-production in the tissues and ventilation from the lungs are stable.
- Trial name
- NCT02070861
- Testing
- Ventricular pacing and passive leg raise
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Oslo University Hospital
Heart Transplant Recipients
Autonomic Cardiovascular Control After Heart Transplantation
The purpose of this prospective study is to investigate denervation (ie. surgical cutting of autonomic nerves) and re-innervation (ie. growth of autonomic nerves) in heart transplant recipients. More specifically, we focus on: 1.
- Trial name
- AccHeart (NCT01759966)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Pneumonia Childhood, Lower Respiratory Tract Infection
The Norwegian Antibiotics for Pneumonia in Children Study
This study evaluates the effect of amoxicillin in the treatment of lower airway infections in preschool children. Half of the patients will receive amoxicillin, while the other half will receive placebo.
- Trial name
- NAPiC (NCT03446534)
- Testing
- Amoxicillin
- Where
- 9 sites in Norway
- Volunteers
- 884 people
- Sponsor
- Oslo University Hospital
Peripheral Artery Occlusion, Hemostasis
Comparison Study of Compression Devices Used in Transradial Coronary Angiography
The transradial route is used in 90% of the coronary angiograms performed at Oslo University Hospital (OUS), Ullevål. A compression device needs to be applied after the procedure to achieve hemostasis.
- Conditions
- Peripheral Artery Occlusion, Hemostasis, Injury of Radial Artery
- Trial name
- NCT02583854
- Testing
- RY-STOP hemostasis device, TR-Band, Terumo
- Where
- Norway
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Pelvic Girdle Pain
Symptoms and Function During and After Pregnancy
The purpose of this study is to: 1. describe degree of symptoms and disability during and after pregnancy 2. to examine if women with pelvic girdle pain are able to correctly mark their pain location on a pain drawing 3.
- Trial name
- NCT01787266
- Where
- Norway
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiovascular Disease, Dietary Modification
Effects of Reduction in Saturated Fat on Cholesterol and Lipoproteins in Lean and Obese Persons
A randomized controlled clinical trial comparing the effect of substitution of unsaturated fat from nuts and oils for saturated fat from meat and dairy foods on serum lipids in normal weight and obese subjects with elevated LDL…
- Conditions
- Cardiovascular Disease, Dietary Modification, Cardiovascular Risk Factors
- Trial name
- NCT02589769
- Testing
- unsaturated fat for saturated fat, saturated fat
- Where
- Norway
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Abdominal Pain
Chronic Abdominal Pain After Gastric Bypass
The study aims to explore patients perception of chronic abdominal pain after Roux en Y gastric bypass surgery for morbid obesity. The investigators aim to describe characteristics of symptoms of pain.
- Trial name
- NCT03455998
- Testing
- questionnaires
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Aortic Valve Disease
The Impact of 24/7-phone Support on Readmission After Aortic Valve Replacement, a Randomized Clinical Trial
Aortic Valve Replacement (AVR) surgery for aortic valve disease continues to increase in numbers. With better surgical techniques and equipment, also older patients can be operated on, resulting in an growth of the older…
- Trial name
- AVRre (NCT02522663)
- Testing
- 24/7-telephone support
- Where
- Norway
- Volunteers
- 288 people
- Sponsor
- Oslo University Hospital
Skin Cancer
Prospective, RCT of Split Thickness Skin Grafts on Lower Leg After Compression Therapy With Compression Bandage vs. NPWT
The single center, prospective, randomized trial includes in total 60 patients. We want to compare two different treatment methods for compression therapy for split thickness skin graft in lower leg.
- Trial name
- NCT03452852
- Testing
- PICO, Coban 2 lite
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hiv, Sexually Transmitted Diseases
Evaluation of Implementation of Pre-exposure Prophylaxis (PrEP) in Norway
Despite the significant preventive efforts to reduce HIV infections in the past decades, the incidence in MSM has plateaued at a higher level after the turn of the millennium.
- Conditions
- Hiv, Sexually Transmitted Diseases, Mental Health Wellness 1
- Trial name
- NCT03436407
- Where
- 9 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Drug Usage
Cooperation for Improved Pharmacotherapy in Home-dwelling Elderly People Receiving Polypharmacy - The COOP Study
Polypharmacy increases the risk of adverse drug effects, interactions and other drug-related problems, and several studies indicate that inappropriate drug use is a major reason for poor health and impaired function in the…
- Trial name
- COOP (NCT02379455)
- Testing
- Comprehensive drug review
- Where
- Norway
- Volunteers
- 192 people
- Sponsor
- Oslo University Hospital
Cancer, Gastrointestinal Cancer
Long-term Cancer Risk in the Randomised Oslo Diet and Antismoking Study
This study examines the effect of a five-year multifactorial lifestyle intervention in the Oslo diet and antismoking study on long-term cancer risk.
- Conditions
- Cancer, Gastrointestinal Cancer, Lung Cancer, Urinary Tract Cancer
- Trial name
- NCT03410641
- Testing
- Diet and antismoking advice
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Tibial Fractures
Reamed Nailing Versus Taylor Spatial Frame in Tibia Shaft Fractures
This is a randomised, bi-centre, prospective, clinical trial in patients with closed tibia shaft fractures. The fracture should be fresh/acute and seen within 3 weeks after the injury.
- Trial name
- NAFTI (NCT03388879)
- Testing
- Taylor Spatial Frame, Intramedullary nail
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Oslo University Hospital
Hypertension
Nesiritide in Hypertension
Hypertension remains a global burden in cardiovascular disease leading to stroke, myocardial infarction, and heart failure. Its myocardial complications result from increased mechanical load on the heart.
- Trial name
- TENSE1 (NCT02608996)
- Testing
- Nesiritide
- Where
- 3 sites in Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Amputation
Early Active Finger Exercises in Replanted Fingers
A controlled randomized trial, including patients undergoing finger replantation surgery. The Control Group will receive a standardized post operative rehabilitation regime, whilst the Intervention Group will receive a…
- Trial name
- NCT03383640
- Testing
- Active exercises
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital