Clinical trials: sponsored by Oslo University Hospital
Pollen; Allergy, Asthma
Does Medicinal Mushroom Agaricus Blazei Protect Against Allergy and Asthma?
Asthma and allergy is increasing in Norway and Western countries. Treatment is still mostly symptomatic. Extracts of the immunomodulatory and edible mushroom Agaricus blazei, such as Andosan™, have been shown to protect against…
- Trial name
- NCT03198455
- Testing
- Agaricus blazei Murill-based mushroom extract, Andosan™
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Soft Tissue Neoplasms, Gastrointestinal Tract
Treatment Response Evaluation in Gastrointestinal Stromal Tumor (GIST) Patients
The purpose of this study is to compare sensitivity, specificity and accuracy of PET, DW MRI and CT separately and combined for the evaluation of treatment response and progression-free survival in patients with GIST.
- Trial name
- NCT01276483
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Colorectal Cancer
The Northern-European Initiative on Colorectal Cancer
Colorectal cancer (CRC) is a major burden in western countries. The disease develops from precursor lesions during a long time-interval.
- Trial name
- NordICC (NCT00883792)
- Testing
- Colonoscopy
- Where
- 7 sites in United States, Iceland and 4 more
- Volunteers
- 95,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Obesity, Morbid
Pharmacokinetics of Propofol in Morbidly Obese Patients
The objectives of this study are To determine PK of propofol in bariatric patients To identify the physiological variables that induce propofol PK changes in bariatric patients, when compared to a normal-weight population.
- Trial name
- NCT01536002
- Testing
- Propofol
- Where
- Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Colorectal Neoplasms
Immunotoxin in Peritoneal Carcinomatosis- ImmunoPeCa Trial
The purpose of this study is through a phase I/II clinical trial to assess the safety and toxicity of intraperitoneally administered MOC31PE immunotoxin, given on the 1.postoperative day after cytoreductive surgery (CRS) and…
- Trial name
- ImmunoPeCa (NCT02219893)
- Testing
- MOC31PE Immunotoxin
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Transposition of Great Vessels, Surgery
MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries
This study involves adolescents operated with arterial switch procedure for transposition of the great arteries during the neonatal period.
- Trial name
- NCT01916499
- Testing
- 3 tesla magnetic resonance imaging findings; coronary artery status, 3 tesla magnetic resonance imaging findings; ventricular function and morphology
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Experiences With HDR-brachytherapy in Norway
There are 3 articles that will be written about the experience with HDR-brachytherapy (HDR-BT) in patients with high-risk prostate cancer in Norway as part of a doctorial thesis-project.
- Trial name
- NCT03162523
- Testing
- High-Dose Rate Brachytherapy
- Where
- Norway
- Volunteers
- 325 people
- Sponsor
- Oslo University Hospital
Maternal Health
Validation of a Midwifery Model in Palestine 1
To validate a model of Continuity of Midwifery Care implemented in the region of Nabuls and Jericho in Palestine in 2013, register data from the Palestinian Ministry of Health will be analyzed for the following indicators related…
- Trial name
- NCT03145571
- Testing
- Continuity of midwifery care
- Volunteers
- 5,760 people
- Sponsor
- Oslo University Hospital
Chronic Illness
Electronic Tool for Interaction Between Patients and Health Professionals
This project's overall objective is to contribute to knowledge and innovation needed to advance ICT-arenas for timely, secure and seamless collaboration between chronically ill patients and appropriate levels of care.
- Trial name
- NCT03109366
- Testing
- Online patient-provider communication service
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Heart Defects,Congenital, Heart Septal Defects, Atrial
Fluid Balance During Closure of Atrial Septal Defect
This project will evaluate fluid balance and oedema formation in children with the same congenital heart disease (Atrial Septal Defect) who will either go through heart surgery with the use of Cardio Pulmonary Bypass and…
- Trial name
- NCT01757743
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Oslo University Hospital
Heart Defects, Congenital, Hypoplastic Left Heart Syndrome
Fluid Balance in Children Undergoing Fontan Surgery
This project will evaluate fluid balance and edema formation in children with congenital heart disease in need of a surgical procedure, The Fontan procedure.
- Trial name
- NCT02306057
- Testing
- Pre BCPC, Pre TCPC, BCPC surgery
- Where
- Norway
- Volunteers
- 39 people
- Sponsor
- Oslo University Hospital
Cervical Cancer
SElf-SAMpling in Cervical Cancer Screening; SESAM Study
Study aims to support development of evidence based health care in Norway through evaluating recently proposed technological improvements in cervical cancer control before their routine use.
- Trial name
- SESAM (NCT02945891)
- Testing
- HPV testing of Evalyn®Brush, FloqSwab and Colli-Pee specimens
- Where
- 4 sites in Norway
- Volunteers
- 310 people
- Sponsor
- Oslo University Hospital
Renal Disease, Peripheral Arterial Disease
The Effects of INP on Peripheral Circulation in Dialysis Patients and Patients With PAD and Leg Ulcers
This experimental study will look at the effects of INP therapy for two patient groups: 1) patients with reduced peripheral circulation and chronic wounds in patients with renal disease (dialysis patients); 2) and peripheral…
- Conditions
- Renal Disease, Peripheral Arterial Disease, Arterial Leg Ulcers
- Trial name
- NCT02622308
- Testing
- FlowOx™
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- Oslo University Hospital
Cancer, Congenital Heart Disease
Supporting Patient Provider Communication in Paediatric Care
Children with Cancer or congenital heart disease (CHD) experience complex, physical, psychosocial and behavioural symptoms and problems due to the illness, treatment, and medical procedures.
- Trial name
- SiSom (NCT01280227)
- Testing
- SiSom
- Where
- Norway
- Volunteers
- 144 people
- Sponsor
- Oslo University Hospital
Adenomyosis
Norwegian Adenomyosis Study I
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED I (NCT02201719)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Gonarthritis
Patient-specific Positioning Guides (PSPG) Technique Versus Conventional Technique in Total Knee Arthroplasty
A Prospective, randomized, clinical controlled study comparing conventional knee arthroplasty and the Patient-specific positioning guides (PSPG) (Signature Patient Care, Materialise) using the Vanguard Total Knee System (Biomet)
- Trial name
- NCT01696552
- Testing
- TKR with Positioning Guides (PSPG), TKR with Conventional Technique
- Where
- 4 sites in Norway
- Volunteers
- 109 people
- Sponsor
- Oslo University Hospital
Lung Neoplasm
Preoperative Loading With Carbohydrates in Lung Cancer Surgery
Administration of preoperative oral carbohydrates are suggested to reduce insulin resistance due to surgical stress. The aim of this study is to investigate whether preoperative oral carbohydrate loading can contribute to lower…
- Trial name
- NCT03070626
- Testing
- PreOp®
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Oslo University Hospital
Hypovolemia
Cerebral Oximetry in Lower Body Negative Pressure
The study aims to describe hemodynamic effects of lower body negative pressure (LBNP). 1. If and how changes in cerebral oxygen saturation (StO2) measured by near infrared spectroscopy (NIRS) relate to changes in blood flow in…
- Trial name
- NCT03009305
- Testing
- Lower body negative pressure, Continuous positive airway pressure, Positive expiratory pressure
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Diabetes Type 1, Endothelial Dysfunction
Cardiovascular Risk Factors After Single Pancreas Transplantation
Patients accepted for the waiting list for single pancreas transplantation suffer from severe glucose instability with hyperglycemia due to diabetes type 1, but do not have significant diabetes-related complications.
- Trial name
- Diamant (NCT02066350)
- Testing
- Single pancreas transplantation
- Where
- Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
SAH
Rehabilitation of Patients After Subarachnoid Hemorrhage
The study's main objective will be to assess which effect early initiated rehabilitation has on the frequency of complications and the level of physical and cognitive functioning after aneurysmal subarachnoid hemorrhage (SAH).
- Trial name
- SAH (NCT01656317)
- Testing
- Early multidisciplinary rehabilitation
- Where
- Norway
- Volunteers
- 171 people
- Sponsor
- Oslo University Hospital