Clinical trials: sponsored by Oslo University Hospital
Aortic Valve Stenosis
Inflammatory Response to Aortic Valve Replacement
A controlled un-randomized trial where the inflammatory response in 18 patients admitted for TAVI procedure is compared to the inflammatory response in 18 patients admitted for conventional surgical valve replacement.
- Trial name
- NCT03074838
- Testing
- Transarterial aortic valve implantation - TAVI, Surgical aortic valve replacement - SAVR
- Volunteers
- 36 people
- Sponsor
- Oslo University Hospital
Testicular Neoplasms
Testicular Cancer and Aerobic and Strength Training
The present study examine the effects of an aerobic and strength training program on cardiorespiratory fitness in testicular cancer (TC) patients during chemotherapy.
- Trial name
- TAST (NCT02577172)
- Testing
- Exercise group, Control group
- Where
- Norway
- Volunteers
- 19 people
- Sponsor
- Oslo University Hospital
Metastatic Colo-rectal Cancer
LOTCOL Study: Local Treatment of Colo-rectal Liver Met
In this study the investigators will include colo-rectal cancer (CRC) patients starting last line of standard palliative chemotherapy.
- Trial name
- LOTCOL (NCT01867918)
- Testing
- Radiofrequency ablation, microwave, radiation therapy, Standard Chemotherapy
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Oslo University Hospital
Cerebral Palsy, Spastic, Diplegic
Stretching and Strength Training for Improved Gait Function in Children With Spastic Cerebral Palsy
The purpose of this randomized and controlled intervention study is to explore the effect of a physiotherapy intervention targeting contract and spastic hamstring muscles in children having bilateral spastic cerebral palsy (CP)…
- Trial name
- NCT02917330
- Testing
- Stretching and progressive strength training
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Inflammatory Bowel Disease, Crohn's Disease
Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease
Drug serum concentrations will be measured at several time-points for inflammatory disease patients treated with anti-TNF agents.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT02073526
- Testing
- Infliximab, adalimumab, certolizumab pegol
- Where
- Norway
- Volunteers
- 1,230 people
- Sponsor
- Oslo University Hospital
PCL
Rehabilitation of Patient With Acute Isolated PCL Rupture
The posterior cruciate ligament injuries (PCL) is rare and rehabilitation methods are varying. The purpose of the study is to explore if one rehabilitation option is preferable to one other for patients with acute PCL injury, by…
- Trial name
- NCT02974205
- Testing
- Jack brace, Rehabilitation, össur brace
- Where
- 2 sites in Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Parkinson's Disease
Effects of Deep Brain Stimulation in Parkinson's Disease
The purpose of this study is to identify factors predicting good results in patients treated with deep brain stimulation for Parkinson's disease.
- Trial name
- NCT00855621
- Testing
- Deep brain stimulation of the subthalamic nucleus
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Heart Transplantation
Imminently Effect of Interval Training With High Intensity (HIT) After Heart Transplantation
High intensity Interval training (HIT) has repeatedly been documented to have superior positive effects on oxygen uptake and general physical health compared to continuous moderate exercise in healthy individuals and patients…
- Trial name
- NCT02602834
- Testing
- interval training, moderate exercise
- Where
- Norway
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Peripheral Vascular Disease
Physical Activity, Function and Quality of Life in Patients After Endovascular Treatment
The purpose of this study is to investigate how systematic physical training after endovascular treatment influence the durability of the endovascular treatment and how it effects physical function, quality of life and future…
- Trial name
- NCT01109732
- Testing
- Systematic physical training with instructor
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Preeclampsia
Hemodynamic Measurements in Women With Serious Preeclampsia
This trial is examining hemodynamic measurements in women with serious preeclampsia.
- Trial name
- NCT00199810
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Oslo University Hospital
Preeclampsia
A Study of Cerebral-circulatory Response to Intravenous Antihypertensive Treatment in Women With Serious Preeclampsia
The purpose of this study is a systematical registration of hemodynamic measurements (cardiac output, blood pressure and systemic vascular resistance) in women with serious preeclampsia.
- Trial name
- NCT00403572
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Hypoxia, in Liveborn Infant, Neonatal Asphyxia
Infant Special Program for In Hospital Resuscitation Education in the Delivery Room
The overall objective is to determine whether a bundled In-hospital Newborn Resuscitation Edu-cation intervention (INSPIRE-D) improves process of care associated with improved newborn survival and neurologic outcomes.
- Conditions
- Hypoxia, in Liveborn Infant, Neonatal Asphyxia, Neonatal Bradycardia
- Trial name
- INSPIRE-D (NCT02347241)
- Testing
- Educational intervention
- Where
- Norway
- Volunteers
- 435 people
- Sponsor
- Oslo University Hospital
Rectal Cancer
Oxaliplatin and 5-FU Based Preoperative Chemoradiation
Oxaliplatin and 5FU based preoperative chemoradiation in rectal cancer.
- Trial name
- LARC-RRP (NCT00278694)
- Testing
- Oxaliplatin, Chemoradiation, 5-FU
- Where
- Norway
- Volunteers
- 109 people
- Sponsor
- Oslo University Hospital
Bronchial Asthma
Pathophysiologic Changes in the Respiratory System After Fire Smoke Inhalation
Fire smoke inhalation may contribute to intrabronchial inflammation, airway obstruction and impaired gas exchange. In this study the investigators will examine if the scope of inhalation injury can be assessed soon after hospital…
- Trial name
- NCT01240707
- Testing
- Fiberoptic bronchoscopy
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Angina Pectoris
Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance
Female patients presenting with persistent chest pain despite no obstructive coronary artery disease have impaired prognosis. Stress tests are often positive or inconclusive.
- Trial name
- NCT01582165
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 66 people
- Sponsor
- Oslo University Hospital
Low Back Pain
Non-Specific Chronic Back Pain; Insight From Spatial Aspects of Lumbar Spinal Muscle Activation
There is evidence for altered muscle activity patterns in individuals with non-specific chronic back pain (NSCBP). It is unknown why these alterations in activation pattern occur and how they may be linked to pain experience and…
- Trial name
- NCT01214213
- Where
- Norway
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Respiratory Failure
Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions
Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation.
- Trial name
- NCT01239433
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Oslo University Hospital
Myocardial Infarction
Postconditioning in ST-elevation Myocardial Infarction
Study objectives: To assess the effects of postconditioning on infarct size in patients with ST-elevation infarction referred to PCI. Study design: Prospective, randomized, open-label study with blinded endpoint evaluation.
- Trial name
- POSTEMI (NCT00922675)
- Testing
- Postconditioning, Control intervention
- Where
- Norway
- Volunteers
- 272 people
- Sponsor
- Oslo University Hospital
Keratoconus, Corneal Ectasia
Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL).
Compare different corneal parameters and visual outcome of corneal collagen cross-linking (CXL) with conventional versus accelerated ultraviolet-A irradiation using riboflavin with hydroxypropyl methylcellulose.
- Trial name
- CXL (NCT02883478)
- Testing
- UV-X 1000 (3 mW/cm²), UV-X 2000 (9 mW/cm²), riboflavin with hydroxypropyl methylcellulose
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Reference Values
Reference Values for Pulse Induced Continuous Cardiac Output (PiCCO) Variables in Children
Pulse induced continuous cardiac output (PiCCO) is an established technology for measurement of advanced hemodynamic variables in critically ill patients.
- Trial name
- NCT01283529
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital