Clinical trials: sponsored by Oslo University Hospital
Feeding and Eating Disorders
Comparing Enhanced Cognitive-behavior Therapy and Family-based Treatment for Adolescents With an Eating Disorder
The goal of this randomized controlled clinical trial is to compare the efficacy of outpatient family-based treatment versus enhanced cognitive behavior therapy for children and adolescents with eating disorders.
- Trial name
- CogFam (NCT06256380)
- Testing
- Enhanced Cognitive-behavior therapy for adolescents with an eating disorder, Family-based therapy for adolescents with an eating disorder
- Where
- 5 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Eating Disorders, Body Image
Virtual Body Project Groups Led by Peers Versus Clinicians
Eating disorders (EDs) are a group of illnesses associated with significant psychological and physiological consequences. Overall, only 20% of individuals with EDs receive treatment and treatment is effective for only about…
- Trial name
- v-BP (NCT05993728)
- Testing
- Body Project, Psychoeducational control
- Where
- Norway
- Volunteers
- 441 people
- Sponsor
- Oslo University Hospital
Psychosis;Schizophrenic
Seven-step Phenomenological Psychotherapy for Self-disorder - a Pilot Study
The goal of this clinical pilot study is to learn how adults with schizophrenia or other non-affective psychotic disorders or psychosis risk syndromes experience a novel psychotherapeutic treatment for self-disorders.
- Trial name
- SSPP-SD-p (NCT06597864)
- Testing
- Seven-step phenomenological psychotherapy for self-disorders
- Where
- 2 sites in Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Knee Osteoarthritis
Stability of Contemporary Knee Arthroplasty
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT02861794
- Testing
- Medacta International, GMK Sphere medially stabilized knee
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Oslo University Hospital
Ligament; Laxity, Knee, Knee Osteoarthritis
Ligament Balancing in Total Knee Arthroplasty
The goal of this interventional pilot study is to evaluate if performing ligament balancing on the medial collateral ligament (MCL) in a more systematical manner with a novel instrument can produce more objective and repeatable…
- Trial name
- BLIS-TKA (NCT06264076)
- Testing
- A novel instrument for ligament balancing in total knee arthroplasty, Novel Instrument for ligament balancing in knee arthroplasty
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Knee Osteoarthritis
Stability of Uncemented Medially Stabilized TKA
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT04017533
- Testing
- GMK Sphere TKR
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Aortic Stenosis, Trans-catheter Aortic Valve Implantation
Optimization of Commissural Alignment During Transcatheter Aortic Valve Implantation With Evolut FX+
Purpose of the Study The purpose of this study is to investigate how a transcatheter aortic valve (TAVI, biological valve prosthesis) can best be positioned in order to avoid blockage of the coronary arteries by the valve…
- Conditions
- Aortic Stenosis, Trans-catheter Aortic Valve Implantation, Commissural Alignment
- Trial name
- ALIGN-EFX (NCT07217691)
- Testing
- Implantation of Evolut FX pluss TAVI device from Medtronic in LAO 25, Implantation of Evolut FX pluss TAVI device from Medtronic in patient specific degree.
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Stroke, Acute
The Oslo Study of Visual Impairment After Stroke (StrokeVIS)
Longitudinal, prospective, single-center observational study of visual impairment after stroke. Population: Patients admitted with acute ischemic stroke at the Regional Stroke Unit at Oslo University Hospital who are assessed to…
- Trial name
- StrokeVIS (NCT05809973)
- Testing
- VISA tool
- Where
- Norway
- Volunteers
- 127 people
- Sponsor
- Oslo University Hospital
Central Retinal Artery Occlusion
TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS)
TENecteplase in Central Retinal Artery Occlusion (TenCRAOS): A Prospective, randomized-controlled, double-dummy, double-blind phase 3 multi-centre trial of TNK 0.25 mg/kg + placebo vs.
- Trial name
- TenCRAOS (NCT04526951)
- Where
- 18 sites in Belgium, Denmark and 4 more
- Volunteers
- 81 people
- Sponsor
- Oslo University Hospital
Graft-Versus-Host Disease
Prevention of GVHD in Patients Treated With Allogeneic SCT: Possible Role of Extracorporeal Photophoresis
The main aim is to test the preventive use of extracorporeal photophoresis (ECP) against development of graft-versus-host disease (GVHD) in patients undergoing allogeneic stem cell transplantation for hematological malignancy.
- Trial name
- GVHD (NCT03204721)
- Testing
- Extracorporeal photophoresis (ECP)
- Where
- Norway
- Volunteers
- 158 people
- Sponsor
- Oslo University Hospital
Pain, Chronic Widespread Pain
Pain Reprocessing Therapy for Chronic Widespread Pain: a SCED Study
Chronic Widespread Pain (CWP) is classified as a Chronic Primary Pain syndrome in the ICD-11 and is considered a major type of nociplastic pain with an estimated prevalence of up to 8-10% in the general population.
- Conditions
- Pain, Chronic Widespread Pain, Chronic Pain, Fibromyalgia
- Trial name
- FOKUS (NCT07050758)
- Testing
- Pain Reprocessing Therapy
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Colon Cancer
Adjuvant Chemotherapy In Elderly With Colon Cancer Stage III
This is a phase 2, randomized study where the aim of the study is to investigate the tolerance of adjuvant chemotherapy, measured by functional decline, after surgery for colon cancer stage III in elderly patients.
- Trial name
- ACE (NCT02978612)
- Testing
- Capecitabine
- Where
- Norway
- Volunteers
- 170 people
- Sponsor
- Oslo University Hospital
Anisomelia, Deformity of Limb
RSA Study on the Behaviour of the Growth Plate During and After Temporary Hemi-epiphysiodesis and Epiphysiodesis
By using radiostereometric analysis (RSA) we will be able to study growth during and after temporary epiphysiodesis and with great accuracy be able to detect asymmetric growth following this procedure.
- Trial name
- NCT04235517
- Testing
- Temporary hemi-epiphysiodesis or epiphysiodesis
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Cardiovascular Diseases
Cardiovascular Remodeling in Living Kidney Donors With Reduced Glomerular Filtration Rate
Chronic kidney disease (CKD) is highly frequent, and patients with advanced CKD are known to have a high risk of developing cardiovascular disease (CVD).
- Trial name
- CENS (NCT03729557)
- Testing
- Nephrectomy
- Where
- Norway
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cholangiocarcinoma Non-resectable, Cholangiocarcinoma Recurrent
En Bloc Resection of the Liver and Pancreas With a "Non-touch" Technique Followed by Liver Transplantation to Improve the Overall Survival in Patients With Non-resectable Hilar Cholangiocarcinoma Beyond the Mayo Clinic Transplant Criteria
Surgery for hilar cholangiocarcinoma (phCCA) remains a significant challenge. The minority of patients who are eligible for resection are exposed to high procedure-related morbidity and mortality, and despite apparent R0…
- Conditions
- Cholangiocarcinoma Non-resectable, Cholangiocarcinoma Recurrent, Liver Transplantation
- Trial name
- SURE-LT (NCT06850753)
- Testing
- Liver transplantation after en bloc resection of the liver and pancreas
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Cancer
Off-label Use of Anti-cancer Drugs in Norway -a Prospective Cohort Study
Off-label drug use, where a marketed drug is used outside its approved indication, may allow early access to new and promising treatments.
- Trial name
- NCT04457713
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Urinary Stone, Renal Colic
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up.
- Conditions
- Urinary Stone, Renal Colic, Obstruction Ureter, Urosepsis
- Trial name
- RISUS_AI (NCT06412900)
- Where
- Norway
- Volunteers
- 522 people
- Sponsor
- Oslo University Hospital
Myeloma
Intensified Treatment With Carfilzomib in Myeloma Patients Still PET-positive After First Line Treatment.
A PET-CT will be performed on patients with myeloma after a standard first-line treatment. The PET-positive patients will receive 4 cycles of Carfilzomb-Revlimid-Dexamethason (KRd), before a new PET-CT will be performed.
- Trial name
- CONPET (NCT03314636)
- Testing
- Carfilzomib, Lenalidomide, PET-CT
- Where
- 4 sites in Denmark, Norway and 1 more
- Volunteers
- 53 people
- Sponsor
- Oslo University Hospital
Breast Cancer, Breast Neoplasms
Establishment of Molecular Profiling for Individual Clinical Routine Treatment Decision in Early Breast Cancer
The present project focuses on how to reduce both over- and under-treatment with adjuvant chemotherapy to a large number of breast cancer patients in Norway.
- Conditions
- Breast Cancer, Breast Neoplasms, Hormone Receptor Positive Tumor
- Trial name
- EMIT (NCT03904173)
- Testing
- Multi-parameter tests
- Where
- 5 sites in Norway
- Volunteers
- 2,300 people
- Sponsor
- Oslo University Hospital
Bardet-Biedl Syndrome
Characterizing the Genotype and Phenotype in Adults With Bardet-Biedl Syndrome
Bardet-Biedl syndrome (BBS; OMIN #209900) is a rare genetic disorder characterized by six core features: rod-cone dystrophy (retinitis pigmentosa), polydactyly, obesity, genital anomalies, renal anomalies, and learning…
- Trial name
- NCT05400278
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo University Hospital