Clinical trials: sponsored by Peking Union Medical College Hospital
Heavy Metal Toxicity, Spontaneous Abortion
the Association Between Blood's and Urinary Heavy Metal Level in Pregnant Women and the Spontaneous Abortion
The aim of the study was to define the possible association between heavy iron level and the consequence of pregnancy especially spontaneous abortion and missed abortion.
- Trial name
- HMLandSA (NCT03332706)
- Testing
- observation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Gonadotropin-Releasing Hormone Agonist for the Preservation of Ovarian Function During Chemotherapy in Premenopausal Breast Cancer
The study is a prospective randomized control clinical trial which is sponsored by the researchers. The purpose of this study is to determine the effectiveness of Gonadotropin-Releasing hormone agonist on ovarian function for…
- Trial name
- POF (NCT02483767)
- Testing
- goserelin, standard chemotherapy
- Volunteers
- 98 people
- Sponsor
- Peking Union Medical College Hospital
Neuroendocrine Tumors
177Lu-DOTA-EB-TATE in Patients With Advanced Neuroendocrine Tumors
This is an open-label, non-controlled, non-randomized study to investigate the long-lasting radiolabeled somatostatin analogue based peptide receptor radionuclide therapy and evaluation safety and dosimetry of 177Lu-DOTA-EB-TATE…
- Trial name
- NCT03308682
- Testing
- 177Lu-DOTA-EB-TATE
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Primary IgA Nephropathy
Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis in the world.There is to date no curative therapy for patients with IgAN.It is considered that dendritic cells, Toll-like receptor (TLR) 9 and…
- Trial name
- HCQIgAN (NCT02765594)
- Testing
- Hydroxychloroquine Sulfate, Valsartan
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Peking Union Medical College Hospital
Renal Artery Stenosis, Renal Blood Perfusion
A Study of Using Parenchymal Blood Volume(PBV) for Endovascular Treatment of Renal Arterial Stenosis
This study will use PBV technique to quantitatively assess the improvement of renal perfusion before and after endovascular treatment (EVT) of renal artery stenosis.
- Trial name
- NCT03252639
- Testing
- EVT for RAS & PBV acquisition protocol for target kidneys
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Sepsis
The Role and Mechanism of Vimentin in Sepsis Patients
Sepsis is the most common cause of death in the clinical critically ill patients. We have successfully screened the sepsis biomarkers by clinical proteomics approach and found that Vimentin (VIM) played an important role in the…
- Trial name
- NCT03253146
- Testing
- VIM detection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Arterial Occlusive Diseases
A Prospective Study: the Value of Using iFlow and PBV in the Endovascular Treatment of Infrapopliteal Arterial Occlusive Diseases
Color coded blood flow and blood perfusion techniques are applied to the endovascular treatment of infrapopliteal arterial occlusion,to establish a method of quantitative evaluation of blood flow and tissue perfusion,to improve…
- Trial name
- NCT03248323
- Testing
- dyna-pbv
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes Mellitus
Identification of Gestational Diabetes Mellitus Related Urinary Biomarkers Along Pregnancy (From Early Pregnancy to Postpartum) by Using Proteomics and Metabolomics Analysis
Gestational diabetes mellitus (GDM) has many adverse effects on pregnant women and fetuses. At present, no prediction marker for GDM in early pregnancy is accepted. There is still a lack of recognized early predictors.
- Trial name
- NCT03246295
- Testing
- lifestyle intervention or insulin treatment
- Volunteers
- 140 people
- Sponsor
- Peking Union Medical College Hospital
HER2-positive Breast Cancer
A Randomized Controlled Trial of HER-2 Positive Breast Cancer Patients Treated With Lapatinib vs Herceptin
This is a randomized controlled trial of HER-2 positive breast cancer patients treated with lapatinib and paclitaxel vs herceptin and paclitaxel with sequential and synchronous anthracycline
- Trial name
- NCT03085368
- Testing
- lapatinib/herceptin
- Where
- China
- Volunteers
- 482 people
- Sponsor
- Peking Union Medical College Hospital
Pneumocystis Jiroveci Pneumonia, Intensive Care Unit
Prospective Registration of Severe Pneumocystis Jiroveci Pneumonia Requiring ICU Admission
the investigators aim to set up a multicenter registry study for severe PJP requiring ICU admission. The purpose of this study is 1.
- Trial name
- NCT03201497
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Takayasu Arteritis, Pulmonary Artery Hypertension
Pulmonary Artery Involvement in Takayasu's Arteritis
The purpose of this study is to analyze the clinical manifestations, imaging features, and prognosis-related factors of pulmonary artery (PA) involvement in Takayasu's arteritis (TA), and to explore the early clinical features of…
- Trial name
- NCT03189602
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Peking Union Medical College Hospital
Prostate Cancer
68Ga-NOTA-RM26 PET/CT in Prostate Cancer Patients
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-RM26 in prostate cancer patients.
- Trial name
- NCT03164837
- Testing
- 68Ga-NOTA-RM26
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes
Breast Milk Hormones and Early Infant Growth of Women With Gestational Diabetes Mellitus
Background: Breastfeeding has been associated with attenuated risk of obesity and type 2 diabetes in children born to women with diabetes.
- Trial name
- NCT03145649
- Testing
- Dietary therapy or insulin injection
- Volunteers
- 96 people
- Sponsor
- Peking Union Medical College Hospital
POEMS Syndrome
Study to Evaluate Lenalidomide Plus Dexamethasone in Patients With Newly Diagnosed POEMS Syndrome
The purpose of this prospective study is to determine the efficacy and safety of lenalidomide plus dexamethasone in patients with newly diagnosed POEMS syndrome.
- Trial name
- NCT01816620
- Testing
- Lenalidomide, Dexamethasone
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Peking Union Medical College Hospital
Multiple Myeloma, Comprehensive Geriatric Assessment
cGA in Newly-diagnosed Elderly MM Patients: a Multi-center, Prospective, Non-interventional Study.
This is a multi-center, prospective, non-interventional study. Eligible newly diagnosed elderly multiple myeloma (MM) patients will receive comprehensive geriatric assessment (cGA) including ECOG scale, questionaires of…
- Trial name
- NCT03122327
- Testing
- Questionaires
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Advanced Well-differentiated Pancreatic Neuroendocrine Tumor
Chemotherapy Plus Endostatin in Advanced Pancreatic Neuroendocrine Tumor
Temozolomide or dacarbazine-based chemotherapy combined with endostatin have efficacy in well-differentiated pancreatic neuroendocrine tumor
- Trial name
- NCT01845675
- Testing
- temozolomide or dacarbazine-based chemotherapy, endostatin
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Peking Union Medical College Hospital
IgG4-related Disease
A Prospective Cohort Study of IgG4RD in China
This is an cohort study to investigate the disease course and treatment response of patients with IgG4-related disease.
- Trial name
- NCT01670695
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Enterobacteriaceae Infections
18F-FDS PET/CT in Healthy Volunteers and Patients With Suspected Infection
This is an open-label dynamic whole-body PET/CT (positron emission tomography/computed tomography) study for investigation of radiation dosimetry, plasma pharmacokinetics, biodistribution, safety and diagnostic performance of…
- Trial name
- NCT02450942
- Testing
- 18F-FDS
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Rheumatoid Arthritis
68Ga-BNOTA-PRGD2 PET/CT in Patients With Rheumatoid Arthritis
This is an open-label positron emission tomography/computed tomography ( PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-BNOTA-PRGD2 in rheumatoid arthritis (RA) patients.
- Trial name
- GRGDRA (NCT01940926)
- Testing
- 68Ga-BNOTA-PRGD2
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Glioma
68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-Aca-BBN(7-14) in glioma patients.
- Trial name
- NCT02520882
- Testing
- 68Ga-NOTA-Aca-BBN, PET/CT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital