Clinical trials: sponsored by Peking University
Depression, Anxiety, Emotional Disorders
Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress
The goal of this clinical study is to learn how Mindfulness Intervention for Emotional Distress (MIED) helps people with emotional distress and how their symptoms and psychological patterns change over time.
- Trial name
- NCT07280481
- Testing
- Mindfulness Intervention for Emotional Distress (self-guided version)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University
Malignant Solid Brain Tumors, Glioblastoma (GBM)
NK Cell Therapy for Malignant Solid Brain Tumors
This is a multi-center, open-label investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, and feasibility of combined intracranial and intravenous administration of ex vivo expanded and activated…
- Conditions
- Malignant Solid Brain Tumors, Glioblastoma (GBM), Glioblastoma Multiforme (GBM), Brain Metastasis
- Trial name
- NCT07552233
- Testing
- Autologous NK cells
- Where
- 4 sites in China
- Volunteers
- 27 people
- Sponsor
- Peking University Third Hospital
Primary Angle-Closure Glaucoma
Predicting the Risk of Partial Ciliary Block After Cataract and Goniosynechialysis Surgery in Primary Angle-Closure Disease
Primary angle-closure disease (PACD) is a major cause of vision loss, often treated with a combined surgery that removes the eye's natural lens (cataract surgery) and physically opens the eye's drainage system…
- Trial name
- PCB-Risk (NCT07549438)
- Volunteers
- 1,150 people
- Sponsor
- Peking University People's Hospital
Atopic Dermatitis (AD)
Efficacy and Safety of Switching to Ivarmacitinib in Patients With Moderate-to-Severe Atopic Dermatitis With Inadequate Response to Interleukin-4 Receptor Alpha(IL-4Rα) Inhibitors: A Prospective, Multicenter, Real-World Study
Atopic dermatitis (AD) is a skin condition characterized by a rash and itching, resulting from skin inflammation. Ivarmacitinib is an approved medication for treating AD.
- Trial name
- NCT07550452
- Testing
- Ivarmacitinib Sulfate Tablets
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Upper Tract Urothelial Carcinoma Receiving Kidney-sparing Therapy, Upper Tract Urothelial Carcinoma
Multimodal Kidney-Sparing Strategy for High-Risk Upper Tract Urothelial Carcinoma
UTUC is a cancer that develops in the lining of the kidney or ureter. The standard treatment is radical nephroureterectomy, which removes the kidney and ureter.
- Trial name
- NCT07504939
- Testing
- SBRT
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Peking University First Hospital
Emotional Disorders, Depressive Disorder
The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders
The goal of this clinical trial is to evaluate the effectiveness and cost-effectiveness of a digital mindfulness-based intervention in adults (aged 18-65) diagnosed with emotional disorders like depression or anxiety.
- Conditions
- Emotional Disorders, Depressive Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT07458100
- Testing
- Mindfulness Intervention for Emotional Distress
- Where
- China
- Volunteers
- 464 people
- Sponsor
- Peking University
Gastric Cancer
ctDNA-MRD Monitoring After Resection in Gastric Cancer
Numerous studies have demonstrated that circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) detection has significant clinical value in postoperative recurrence monitoring, adjuvant treatment decision-making, and…
- Trial name
- MRD-GC (NCT06893133)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University
Atherosclerotic Cardiovascular Disease (ASCVD), Secondary Prevention
Aspirin 50 mg vs. 100 mg in Elderly Cardiovascular Disease Patients
Elderly patients with cardiovascular disease face a high risk of both thrombotic and bleeding events when receiving antithrombotic therapy.
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Secondary Prevention, Cardiovascular Diseases
- Trial name
- LAPIS (NCT07542860)
- Where
- China
- Volunteers
- 5,448 people
- Sponsor
- Peking University First Hospital
Radiation Therapy, Metastatic Renal Cancer
CAIX PET/ CT Guided Radiation Therapy in CcRCC.
This is a prospective, single-arm study in adults with recurrent or metastatic clear cell renal cell carcinoma (ccRCC). Participants will receive standard systemic therapy (targeted therapy plus anti-PD-1 immunotherapy) and…
- Conditions
- Radiation Therapy, Metastatic Renal Cancer, Recurrent Renal Cell Cancer
- Trial name
- COSTAR-002 (NCT07540260)
- Testing
- PETCT-guided radiation therapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University First Hospital
Breast Cancer
Optimization of Dynamic Neoadjuvant Therapy Strategies for HER2-Positive Breast Cancer Based on HER2-PET/CT Molecular Imaging
This study evaluates HER2-PET/CT-guided dynamic optimization of neoadjuvant therapy in patients with early-stage HER2-positive breast cancer.
- Trial name
- NCT07527806
- Testing
- Trastuzumab (Herceptin), Pertuzumab, Combination product: Trastuzumab + Pertuzumab
- Volunteers
- 156 people
- Sponsor
- Peking University Cancer Hospital & Institute
Acute Myeloid Leukemia (AML), MLL Rearrangement
Leukemia Stem Cell-based Assay to Predict Relapse and Survival in Patients With Acute Myeloid Leukemia
The goal of this observational study is to learn about the predict value of leukemia stem cell for acute myeloid leukemia patients with MLL-rearrangement.
- Trial name
- MLL-LSC (NCT07537738)
- Testing
- Detection of leukemia stem cell using multiparameter flow cytometry
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Peking University People's Hospital
Arthritis, Rheumatoid
Fucoidan in the Treatment of Active Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint destruction and autoantibody production. Scavenger receptor-A (SR-A), a pattern recognition receptor primarily expressed on myeloid-derived cells…
- Trial name
- NCT07045896
- Testing
- Fucoidan
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University People's Hospital
Diabetic Foot
Platelet Rich Plasma VS Platelet Fibrin Plasma in Treatment of Diabetes Related Wound：a Randomized Controlled Trial
The goal of this randomized control trial is to compare the efficacy and safety of Platelet Rich Plasma VS Platelet Fibrin Plasma in patients with diabetes foot ulcer.
- Trial name
- NCT05979584
- Testing
- Platelet Fibrin Plasma, Platelet Rich Plasma
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Peking University Third Hospital
Spinal Surgery, Pain Intensity
Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery
Spinal surgery is generally followed by severe postoperative pain, and poor pain control may cause adverse outcomes such as cardiovascular events, neurocognitive disorders, and chronic postsurgical pain (CPSP).
- Conditions
- Spinal Surgery, Pain Intensity, Dexmedetomidine, Esketamine
- Trial name
- NCT07525999
- Testing
- Combined dexmedetomidine-esketamine administration
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Peking University First Hospital
Gastrointestinal Stromal Tumor of Stomach, Submucosal Tumor of Stomach
MCB vs EUS-FNA for Preoperative Pathological Evaluation of Gastric SMT
Gastrointestinal stromal tumors (GISTs) are the most common submucosal tumors (SMTs) of the stomach. The 2022 European Society of Oncology ESMO Diagnosis and Treatment Guidelines recommend that GISTs undergo biopsy with a clear…
- Trial name
- NCT06748690
- Testing
- mucosal cutting biopsy, endoscopic ultrasound-guided-fine needle aspiration
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Multiple Myeloma
PET Imaging Study of 68Ga-NB381 in Multiple Myeloma
Multiple myeloma (MM) predominantly affects the elderly, often presenting insidiously and with a rising incidence rate. Current diagnostic methods primarily rely on invasive bone marrow biopsies, which can lead to false-negative…
- Trial name
- NCT06385652
- Testing
- 68Ga-NB381
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Pelvic Lipomatosis, Cystitis Glandularis
Efficacy of UMT in CG Patients With PL
To clinically validate the pathological role of Cer accumulation and evaluate a novel microbiota-targeted intervention, we conducted a comprehensive analysis of bladder mucosal specimens from a well-characterized patient cohort…
- Trial name
- NCT07530627
- Testing
- Urinary Microbiota Transplantation (UMT)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Anterior Cruciate Ligament Rupture
Effects of Preoperative Rehabilitation on Tendon Healing, Bone Mineral Density, and Cartilage After ACLR and Patellar Dislocation
To explore the effect of preoperative exercise rehabilitation on bone mineral density, tendon bone healing, change of cartilage, and gait feature in patients with anterior cruciate ligament rupture.
- Trial name
- NCT05924178
- Testing
- exercise rehablitation, routine treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Ovarian Cancer, Breast Cancer
A Bidirectional Cohort Study on Prophylactic Resection Surgery in Populations at Moderate-to-High Risk for Hereditary Ovarian Cancer
The goal of this multi-center observational study is to learn about the effectiveness and safety of different prophylactic (preventive) surgical options in women at moderate-to-high genetic risk for hereditary ovarian cancer…
- Trial name
- NCT07532434
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking University Third Hospital
Spinal Surgery, Pain Intensity
Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery
Spinal surgery is generally followed by severe postoperative pain, and poor pain control may cause adverse outcomes such as cardiovascular events, neurocognitive disorders, and chronic postsurgical pain (CPSP).
- Conditions
- Spinal Surgery, Pain Intensity, Dexmedetomidine, Esketamine
- Trial name
- NCT07523321
- Testing
- Combined dexmedetomidine-esketamine administration
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Peking University First Hospital
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