Clinical trials: sponsored by Peking University
Attention Deficit Hyperactivity Disorder
Concerta and Strattera on the Executive Function in Attention Deficit Hyperactivity Disorder (ADHD) Children
The objective of this study is to compare the effect of Concerta (Osmotic Release Oral System Extended Release Methylphenidate HCL, OROS MPH) and Strattera (Atomoxetine) on the laboratory and ecological executive function in…
- Trial name
- NCT01065259
- Testing
- OROS MPH, Atomoxetine
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Peking University
SCCHN
Safety and Efficacy Study of Target Therapy Combined With Radiotherapy to Treat Senile Locally Advanced SCCHN
Radiotherapy alone is generally the only treatment in old patients with SCCHN. No evidence indicates combination with EGFR Target therapy can bring benefit for the patients.
- Trial name
- NCT01393184
- Testing
- Nimotuzumab and Radiotherapy
- Volunteers
- 92 people
- Sponsor
- Peking University
Attention Deficit Hyperactivity Disorder
Associated Genes With Atomoxetine Response in Attention Deficit Hyperactivity Disorder (ADHD)
Attention deficit hyperactivity disorder (ADHD) is the most common behavior disorder, with the prevalence of 3% to 6% in children and adolescents. The patients' academic achievements, professions and social livings are impaired.
- Trial name
- NCT01339286
- Testing
- atomoxetine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Esophageal Squamous Cell Cancer
Nimotuzumab Plus Paclitaxel and Cisplatin as 1st Line Treatment for Esophageal Squamous Cell Cancer
Nimotuzumab, as one new agent used in advanced esophageal carcinoma, has been shown to be effective and safe in some studies with head-neck cancers.
- Trial name
- NCT01336049
- Testing
- Nimotuzumab
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University
Metastatic Melanoma
Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic Melanoma
This study is a single-armed, open-label, single-center phase II trial of signal transduction inhibitor number 571 (STI-571) systemic therapy in selective patients with metastatic melanoma, and aims to study the efficacy and…
- Trial name
- NCT00881049
- Testing
- Imatinib (Gleevec)
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Peking University
Multiple Myeloma
Technology Platform and System Construction of Clinical Evaluation Studies on New Drugs of Hematological Malignancy
Multiple Myeloma (MM) is the second diagnosed malignancy of hematological malignancies. The previous study pointed out that the dosage and course of Bortezomib including the dose of concomitant drugs used to treatment MM patients…
- Trial name
- NCT01250808
- Testing
- Bortezomib/Dexamethasone/Melphalan
- Where
- China
- Sponsor
- Peking University
Schizophrenia
Standard Comprehensive Intervention to Treat First-episode Schizophrenia
Schizophrenia is not a curable but a treatable disease by antipsychotics. Kinds of atypical antipsychotics are widely used since 1990s' in China.
- Trial name
- NCT01057849
- Testing
- risperidone, olanzapine, Aripiprazole
- Where
- 6 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University
Advanced Esophageal Squamous Carcinoma
Irinotecan Combined With Cisplatin as 1st Line Treatment for Esophageal Squamous Cell Cancer : a Single Center Prospective Clinical Trial
Irinotecan, as one new agent used in advanced esophageal carcinoma, has been shown to be effective and safe in western studies. Different with westerns, squamous carcinoma is the main pathological type in china patients.
- Trial name
- NCT01051765
- Testing
- irinotecan/cisplatin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University
Advanced Esophageal Carcinoma
mFOLFIRI as the Second Line Chemotherapy for Advanced Esophageal Carcinoma After Failure of 1st Line Treatment of Paclitaxel/DDP : a Phase II Single Center Prospective Clinical Trial
There are few studies about 2nd line treatment in advanced esophageal carcinoma(AEC), some showed that irinotecan may be effective.
- Trial name
- NCT01044420
- Testing
- mFOLFIRI
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University
Amyotrophic Lateral Sclerosis
Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response
This study will examine the effectiveness of Cistanche Total Glycosides(CTG) in treating patients with amyotrophic lateral sclerosis (ALS) - a fatal neurological degenerative disease that causes adult-onset, progressive motor…
- Trial name
- NCT00753571
- Testing
- Cistanche Total Glycosides
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University
Advanced Colorectal Cancer
Study of Nimotuzumab to Treat Colorectal Cancer
Nimotuzumab is an IgG1 humanized monoclonal antibody that recognized an epitope located in the extra cellular domain of the human epidermal growth factor receptor (EGFR).
- Trial name
- NCT00972465
- Testing
- Nimotuzumab and chemotherapy
- Where
- 3 sites in China
- Volunteers
- 48 people
- Sponsor
- Peking University
Stomach Neoplasms, Gastric Cancer
Study of Oxaliplatin, Calcium Folinate, and 5-Fluorouracil as Neoadjuvant Chemotherapy for Resectable Advanced Gastric Cancer
This is a randomized phase II multicenter controlled study of oxaliplatin, calcium folinate, and 5-fluorouracil (mFOLFOX7) as neoadjuvant chemotherapy for resectable advanced gastric cancer.
- Trial name
- NCT00591045
- Testing
- mFOLFOX
- Where
- China
- Volunteers
- 263 people
- Sponsor
- Peking University
Amyotrophic Lateral Sclerosis
G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response
This study will examine the effectiveness of G-CSF in treating patients with amyotrophic lateral sclerosis (ALS) - a fatal neurological degenerative disease that causes adult-onset, progressive motor neurons loss in the spinal…
- Trial name
- NCT00397423
- Testing
- Granulocyte Colony Stimulating Factor, NS
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University
Retinal Detachment
Pneumatic Retinopexy Versus Vitrectomy With Gas for Retinal Detachment Due to Myopic Macular Hole
To undertake a prospective randomized clinical study for treating retinal detachment due to myopic macular holes, utilizing pneumatic retinopexy versus pars plana vitrectomy with gas tamponade.To determine the efficiency of…
- Trial name
- RDMH (NCT00485199)
- Testing
- Pneumatic Retinopexy, Vitrectomy with Gas
- Where
- 14 sites in China
- Volunteers
- 231 people
- Sponsor
- Peking University
Invasive Fungal Infection, Aspergillosis
Evaluate Three Methods for Diagnosis of Invasive Fungal Infection in Chinese Patients After HSCT
The purpose of this study is to assess the cut-off value of GM/G test in Chinese patients after hematopoietic stem cell transplantation, and evaluate GM/G test and real-time PCR for diagnosis of IFI in Chinese patients.
- Conditions
- Invasive Fungal Infection, Aspergillosis, Fungemia, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT00460330
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Glomerulonephritis, IGA
ACEi/ARB Alone Versus ACEi/ARB Plus Steroids in the Treatment of Primary IgA Nephropathy, a RCT
IgA nephropathy( IgAN) is the most common primary glomerulonephritis worldwide. Since the etiology of the disease is not clearly understood, no specific therapeutic strategies was defined for IgAN.
- Trial name
- NCT00378443
- Testing
- prednisone + Inhibace/Cozaar, Inhibace/Cozaar
- Sponsor
- Peking University
Idiopathic Membranous Nephropathy, Nephrotic Syndrome
Tacrolimus Combined With Prednisone Treatment of Idiopathic Membranous Nephropathy and Nephrotic Syndrome
Idiopathic membranous nephropathy (IMN) is one of the most common forms of nephrotic syndrome (NS) in adults and is usually treated by corticosteroids in combination with cytotoxic drugs especially cyclophosphamide or…
- Trial name
- NCT00362531
- Testing
- tacrolimus combined with prednisone
- Sponsor
- Peking University
Nephritis, Lupus
Induction Treatment of Proliferative Lupus Nephritis With Leflunomide Combined With Prednisone
lupus nephritis accounts for the most morbidity and mortality in patients with SLE. Glucocorticoids combined with cyclophosphamide (CYC) are effective for the treatment of patients with proliferative lupus nephritis and have been…
- Trial name
- NCT00268567
- Testing
- leflunomide combined with prednisone
- Where
- 8 sites in China
- Sponsor
- Peking University