Clinical trials: sponsored by Peking University
Esophageal Squamous Cell Cancer
Toripalimab with Paclitaxel and Cisplatin As Neoadjuvant Treatment for Esophageal Squamous Cell Carcinoma
Neoadjuvant chemoradiotherapy or chemotherapy followed by surgery is the standard treatment for local advanced esophageal cancer (EC).
- Trial name
- NCT04804696
- Testing
- Toripalimab, Paclitaxel, Cisplatin
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking University
Olfactory Dysfunction, Chronic Rhinosinusitis
The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can treat postoperative olfactory dysfunction in…
- Trial name
- NCT06837051
- Testing
- Conventional olfactory training device, Modified olfactory training device, Budesonide irrigation
- Where
- China
- Volunteers
- 213 people
- Sponsor
- Peking University Third Hospital
Alzheimer's Disease
Rivastigmine Mini-Tablet for Alzheimer's Disease
The objective of this study is to evaluate the efficacy and safety of rivastigmine mini-tablets in individuals diagnosed with mild to moderate Alzheimer's disease (AD).
- Trial name
- NCT06828289
- Testing
- Rivastigmine Mini-Tablet, Donepezil Hydrochloride
- Volunteers
- 1,000 people
- Sponsor
- Peking University First Hospital
Chronic Rhinosinusitis (CRS)
Impact of Structural and Microenvironmental Abnormalities in Olfactory Cleft on Olfaction in CRS
The purpose of this research is to investigate the impact of structural abnormalities and microenvironmental changes in the olfactory cleft on olfactory function in patients with chronic rhinosinusitis (CRS).
- Trial name
- NCT06834477
- Testing
- Computed Tomography
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Intensive Care Unit, Acute Kidney Injury
The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU
The goal of this study is to quantitatively assess renal microcirculation changes by contrast-enhanced ultrasound and to obtain systemic hemodynamic information by ultrasound Doppler at the same time, to analyze the relationship…
- Conditions
- Intensive Care Unit, Acute Kidney Injury, Ultrasound
- Trial name
- NCT06341062
- Testing
- Renal microcirculation quantitatively assessed by Contrast-enhanced ultrasound
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Peking University Third Hospital
Olfactory Dysfunction, Post Viral Olfactory Dysfunction (PVOD)
The Efficacy of Modified Olfactory Training Method for Patients With Post-viral Olfactory Dysfunction
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is the modified olfactory training device effective in treating patients with…
- Trial name
- NCT06829706
- Testing
- Conventional olfactory training device, Modified olfactory training device
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University Third Hospital
Neoplasms, Gynaecological Oncology
Impact of Pharmacy Services on Gynaecology Chemotherapy Safety
What was studied? We wanted to see whether having pharmacists closely involved in cancer care improves medication safety and reduces severe side effects for patients with gynecologic cancers (like ovarian or uterine cancer)…
- Trial name
- NCT06826950
- Testing
- comprehensive pharmaceutical care, Routine pharmaceutical services
- Where
- China
- Volunteers
- 629 people
- Sponsor
- Peking University First Hospital
Dry Eye
The Effect of 0.05% CsA Eye Drops on Diabetic Patients with Dry Eye Disease
The objective of this study is to observe the effects of 0.05% cyclosporine eye drops combined with artificial tears on patients with diabetes-associated dry eye, and to monitor changes in ocular surface characteristics and…
- Trial name
- NCT06824844
- Testing
- artificial tear eyedrops, 0.05% cyclosporine eyedrops
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Advanced Solid Tumors, Ovarian Cancers
Allogeneic B7H3 CAR-γδT Cell Therapy for Advanced Solid Tumors
γδT cells can directly recognize non-peptide tumor antigens, such as IPP phosphorylated metabolites, without relying on specific major histocompatibility complexes (MHCs).
- Conditions
- Advanced Solid Tumors, Ovarian Cancers, Peritoneal (metastatic) Cancer
- Trial name
- NCT06825455
- Testing
- Fludarabine, Cyclophosphamide, B7H3 CAR-γδT cells
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Peking University
Subjective Cognitive Decline (SCD), Olfactory Dysfunction
The Efficacy of Modified Olfactory Training for MCI High-Risk Individuals
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can delay the progression of MCI in older…
- Conditions
- Subjective Cognitive Decline (SCD), Olfactory Dysfunction, Mild Cognitive Impairment (MCI), ELDERLY PEOPLE
- Trial name
- NCT06821828
- Testing
- Modified olfactory training device, Conventional olfactory training device
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Effect of Preoperative Exercise Habits on Knee Function and Recurrence Rate After Anterior Cruciate Ligament Reconstruction
The aim of this study is to compare the knee function between patients with and without preoperative exercise habits at 1, 2 and 5 years after ACL surgery, and further analyze the effect of maintaining exercise habits on knee…
- Trial name
- NCT06608394
- Testing
- no intervention
- Where
- China
- Volunteers
- 361 people
- Sponsor
- Peking University Third Hospital
Knee Osteoarthritis
Evaluation of the Effect of SURGICEL® Powder in TKA
The study subjects are patients in our hospital's orthopedics department undergoing unilateral primary total knee arthroplasty (TKA) due to primary osteoarthritis.
- Trial name
- NCT06608992
- Testing
- SURGICEL® Powder
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Peking University Third Hospital
Amyotrophic Lateral Sclerosis (ALS)
Individualized Functional Imaging-Guided Repetitive Transcranial Magnetic Stimulation (rTMS) for Treating Postural Gait Disorders in Patients with Amyotrophic Lateral Sclerosis (ALS): a Randomized, Crossover, Controlled, Double-Blind Clinical Study
This study is a randomized, crossover, controlled, double-blind clinical trial. Patients (n=45) were randomly divided into Group A and Group B.
- Trial name
- iFIRST-ALS (NCT06819358)
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 45 people
- Sponsor
- Peking University Third Hospital
Gastric Cancer, Peritoneal Metastases
Laparoscopic Staging for Locally Advanced Gastric Cancer in Chinese Patients
RATIONALE: Laparoscopic staging may help doctors plan more effective treatment for gastric cancer, yet the efficiency have not been fully investigated in Chinese people.
- Trial name
- NCT02172690
- Testing
- Laparoscopic Staging
- Where
- China
- Volunteers
- 452 people
- Sponsor
- Peking University
Acute Myeloid Leukemia
Interferon-alpha As Maintenance Therapy for Favorable-risk Acute Myeloid Leukemia
This research focuses on a prospective, randomized, controlled trial of "Interferon-alpha as maintenance therapy for favorable-risk acute myeloid leukemia." By fully utilizing prospective, randomized, controlled clinical trial…
- Trial name
- NCT06802718
- Testing
- Interferon
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Aging
Targeting Aging and Promoting Longevity with Exogenous Nucleotides (TALENTs)
To investigate the effects of dietary nucleotides (NTs) as an anti-aging supplement, a clinical trial is carried as a randomized, double-blind, parallel design, placebo-controlled.
- Trial name
- NCT05243108
- Testing
- dietary nucleotides
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Peking University
Upper Tract Urothelial Carcinoma
HEFTME System for Adjuvant Therapeutic Selection of Locally Advanced UTUC Postoperatively：A Perspective Cohort Study
This multicenter, real-world study introduces a novel Hematoxylin-eosin staining(H\&E)-based four tumor microenvironment (TME) system (HEFTME system) assisting in prognostic prediction and precise adjuvant treatment selection for…
- Trial name
- NCT06798246
- Testing
- Chemotherapy, Immunotherapy, ADC
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
PMMR/MSS Adenocarcinoma of the Colon or Rectum, Neoadjuvant Chemoradiotherapy
Study on the Applicability of CCR Criteria in Rectal Cancer
This study aims to explore how well the usual ways of checking if rectal cancer patients are free of disease signs after treatment work for a new treatment method.
- Conditions
- PMMR/MSS Adenocarcinoma of the Colon or Rectum, Neoadjuvant Chemoradiotherapy, Immunotherapy, Complete Response
- Trial name
- NCT06794099
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Peking University Cancer Hospital & Institute
Malignant Spinal Cord Compression
The Clinical Efficacy of CT-Guided All-in-One Adaptive Emergency Radiotherapy for Spinal Cord Compression Caused by Spinal Metastases
The aim of this study is to implement a new protocol for concurrent and sequential dose-escalation radiotherapy based on CT-guided all-in-one adaptive emergency radiotherapy for spinal cord compression due to spinal metastases…
- Trial name
- NCT06608108
- Testing
- Non-intervention
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Esophageal Cancer, Gastric Cancer
Effectiveness of Risk-based Sequential Screening for Esophageal and Gastric Cancer
To evaluate the feasibility, applicability, effectiveness, and health-economic value of the risk-based sequential screening modality for esophageal and gastric cancers, the investigators aim to initiate a community-based…
- Conditions
- Esophageal Cancer, Gastric Cancer, Precision Screening, Sequential Screening
- Trial name
- ERSS-EGC (NCT06306755)
- Testing
- Risk Assessment and Individualized Surveillance, Universal screening
- Where
- China
- Volunteers
- 21,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
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