Clinical trials: sponsored by Peking University
Solid Tumor
CD147 Targeting Peptide Probe for PET Imaging in Solid Tumors
The objective of the study is to construct a noninvasive approach using 68Ga-DOTA-AP9 PET/CT to detect the CD147 expression of tumor lesions in patients with solid tumors and to identify patients benefiting from CD147 targeting…
- Trial name
- NCT06720298
- Testing
- 18F-FDG
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Invasive Aspergillosis, Antifungal Therapy
Treatment Duration of IPA
The goal of this observational study is to identify the duration of posaconazole-initiated antifungal treatment for IPA in patients with hematological malignancies and to explore the value of monitoring immune factors and cells…
- Trial name
- NCT06583512
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Peking University People's Hospital
Advanced Esophageal Carcinoma
A Prospective, Randomized, Open, Phase II Clinical Study of Chidamide in Combination with Camrelizumab and Apatinib for Advanced Esophageal Cancer
This study aims to evaluate the efficacy and safety of a combination treatment of chidamide, camrelizumab, and apatinib in patients with advanced esophageal cancer.
- Trial name
- NCT06745193
- Testing
- chidamide+Camrelizumab+Apatinib, Irinotecan or Docetaxel or Paclitaxel
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Peking University
Thrombopenia, Cervical Cancer
Herombopag for the Prevention of Radio-chemotherapy Induced Thrombocytopenia in Cervical Cancer
Exploring and evaluating the efficacy of herombopag in preventing thrombocytopenia due to radiotherapy for cervical cancer
- Conditions
- Thrombopenia, Cervical Cancer, Radiotherapy Side Effect, Chemotherapeutic Toxicity
- Trial name
- NCT06745219
- Testing
- herombopag
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
T Lymphoblastic Lymphoma
Allo-HSCT vs ASCT in Adult T-LBL
Autologous hematopoietic stem cell transplantation (ASCT) is the important consolidation for adult T-LBL. Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is also the important consolidation for adult T-LBL.
- Trial name
- TROPHY-NHL01 (NCT06741813)
- Testing
- ASCT, Allo-HSCT
- Volunteers
- 230 people
- Sponsor
- Peking University People's Hospital
Neoplasms
PET Imaging of 68Ga-Her2-affibody in Tumors with High Her2 Expression
This project uses HER2 protein as the target group of radiodrugs to explore the diagnostic efficacy, safety and metabolic characteristics of 68Ga-Her2-affibody in the expression status of HER2, aiming to provide a new imaging…
- Trial name
- NCT06289517
- Testing
- 68Ga-Her2-affibody
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
SCLC,Extensive Stage
Molecular Subtyping of Extensive Stage Small Cell Lung Cancer and Relevent Clinical Significance
To validate the predictive value of transcriptome-based molecular subtyping of extensive stage small cell lung cancer (SCLC) for the efficacy of programmed death-1(PD-1)/programmed death-ligand1(PD-L1) inhibitor in the first line…
- Trial name
- MOSAIC (NCT05933863)
- Testing
- PD-(L)1 antibody immunotherapy
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Peking University Cancer Hospital & Institute
Colorectal Neoplasms, Colorectal Surgery
Attitudes and Technical Maneuvers Regarding Enterostomy Management and Stoma Creation Among Surgeons
This study was aiming to investigate Chinese surgeons' attitudes toward and technical preferences for stoma creation.
- Trial name
- NCT06735729
- Where
- China
- Volunteers
- 401 people
- Sponsor
- Peking University Cancer Hospital & Institute
Breast Cancer
Study of Preservation of Ovarian Reserve During Chemotherapy for Young Breast Cancer Patients
The purpose of this study is to assess efficacy of gonadotropin-releasing hormone agonist (goserelin) on the preservation of ovarian reserve function in young breast cancer patients treated with (neo)adjuvant chemotherapy by…
- Trial name
- NCT02430103
- Testing
- Goserelin 3.6 MG
- Where
- China
- Volunteers
- 349 people
- Sponsor
- Peking University People's Hospital
Long COVID, COVID-19 Pandemic
Long COVID and Its Associations With Health Outcomes in Older Adults
The Peking University Health Cohort in Anning, Yunnan (PKUHC-AN) is a prospective cohort study carried out in Anning, Yunnan. The primary aim of this study is to investigate the impact of COVID-19 on older adults' health, and to…
- Conditions
- Long COVID, COVID-19 Pandemic, Elderly Infection, Vaccine Reaction
- Trial name
- NCT05825651
- Testing
- no interventions
- Where
- China
- Volunteers
- 11,527 people, healthy volunteers welcome
- Sponsor
- Peking University
Depression - Major Depressive Disorder, Schizophrenia Disorders
Development and Application of Precision Treatment Strategies for Common Mental Disorders
Schizophrenia (SCH), major depressive disorder (MDD), and bipolar disorder (BPD) are prevalent, disabling psychiatric conditions that not only cause significant suffering for affected individuals and their families but also…
- Conditions
- Depression - Major Depressive Disorder, Schizophrenia Disorders, Bipolar Disorder (BD)
- Trial name
- NCT06729541
- Testing
- Multigenetic Pharmacogenomics-Guided Treatment (MPGT)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Immune Thrombocytopenia, Thrombotic Thrombocytopenic Purpura
Longitudinal Cohort of Thrombosis and Hemostasis Diseases
This is a multicenter, prospective, longitudinal, observational cohort study to investigate thrombosis and hemostasis diseases in Chinese patients.
- Conditions
- Immune Thrombocytopenia, Thrombotic Thrombocytopenic Purpura, Hemophilia A, Acquired, Disseminated Intravascular Coagulation
- Trial name
- NCT06727669
- Where
- 5 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Diabetic Retinopathy
Prospective Cohort Study on Predicting the Progression of Diabetic Microangiopathy Using Multimodal Eye Imaging
To develop an artificial intelligence (AI) model to predict DR progression based on a prospective cohort database.With use of an innovative AI model and a validated machine learning algorithm, based on multimodal vascular and…
- Trial name
- NCT06727955
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Peking University Third Hospital
Advanced Malignant Solid Tumors
A Clinical Research About CD70-targeted CAR-NKT Cells Therapy in Subjects with Advanced Malignant Solid Tumors
This is a phase I, open-label, single-arm study conducted to evaluate the efficacy, safety and PK of CGC738 in the treatment of advanced malignant solid tumors.
- Trial name
- NCT06728189
- Testing
- CAR-NKT Cells treatment
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Cancer Hospital & Institute
Breast Cancer, Collagen Protein
Impact of Recombinant Humanized Type III Collagen on the Immediate and Long-term Effects of Breast Tumor Surgery
Breast tumors, particularly breast cancer, are increasingly prevalent in China, with a noticeable trend towards younger ages. Preliminary research indicates that Type III Collagen (COL3) plays a crucial role in tissue and organ…
- Trial name
- ColBreast (NCT06725082)
- Testing
- Recombinant Humanized Type III Collagen Injection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Emotional Distress
Mechanisms of Mindfulness Intervention：Rumination Behavioral Experiments
This study hopes to explore whether the changes in rumination exhibited in behavioral experiments mediates the effects of mindfulness intervention on alleviating emotional distress
- Trial name
- NCT06722573
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)-normal version
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Peking University
Prenatal Depression, Ketamine
Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth
Postpartum depression refers to the depression after childbirth, which is a common mental disorder in women. The pathogenesis of postpartum depression is not fully understood, and may be related to a variety of factors.
- Conditions
- Prenatal Depression, Ketamine, Postpartum Depression
- Trial name
- NCT05698394
- Testing
- Esketamine
- Where
- 4 sites in China
- Volunteers
- 364 people
- Sponsor
- Peking University First Hospital
Cancer
68Ga-HSA PET/CT Imaging for Protein-losing Enteropathy
In this project, based on the DTPA-HAS kit, investigators plan to develop a positron nuclide 68Ga labeled DTPA-HSA molecular probe in order to obtain high sensitivity, signal-to-noise ratio and high-resolution PET/CT imaging…
- Trial name
- PLE-PET (NCT06716788)
- Testing
- 68Ga-HSA
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Cancer Hospital & Institute
Cancer
68Ga-grazytracer PET/CT of Tumor Responses to Immunotherapy
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the safety and clinical predictive value of 68Ga-grazytracer in subjects with solid tumor or lymphoma receiving immunotherapy.
- Trial name
- NCT05000372
- Testing
- 68Ga-grazytracer
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Peking University Cancer Hospital & Institute
HepatoCellular Carcinoma, Portal Vein Thrombosis
Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC with Major Portal Vein Tumor Thrombosis
According to the Barcelona clinic liver cancer (BCLC) staging treatment guideline, sorafenib is recommended for Hepatocellular Carcinoma (HCC) with Portal Vein Tumor Thrombosis (PVTT), but HCC with major PVTT (in the main trunk…
- Trial name
- NCT03009461
- Testing
- HAIC, Sorafenib
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University
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