Clinical trials: sponsored by Peking University
Sjögren's Syndrome
Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome
The purpose of this paper is to analysis of therapeutic effect and immunological mechanism of low-dose IL-2 combined with rapamycin in the treatment of Sjogren's syndrome
- Trial name
- NCT05605665
- Testing
- low-dose interleukin-2, rapamycin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Acute Myocardial Infarction, Coronary Artery Disease
Survival and cArdiovascular eVents in Patients With Acute Myocardial Infarction
This prospective and prospective cohort study aims to establish a long-term follow-up cohort of patients with acute myocardial infarction, and combine multi-omics studies, wearable devices, artificial intelligence technology…
- Trial name
- SAVING (NCT06489080)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Peking University First Hospital
Chronic Atrophic Gastritis
Objective Study on Tongue Diagnosis of Chronic Atrophic Gastritis
Chronic atrophic gastritis with intestinal metaplasia or dysplasia is called precancerous lesions of gastric cancer ( PLGC ). It is an important stage in the transformation of normal mucosa to gastric cancer and is significantly…
- Trial name
- NCT06489132
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
CLL
The Real World Study of Zanubrutinib in the Treatment of Chronic Lymphocytic Leukemia in China
This is a Multicenter, Retrospective Real-world Study of Zanubrutinib in the Treatment of Chronic Lymphocytic Leukemia in China
- Trial name
- NCT06489184
- Testing
- Zanubrutinib
- Where
- China
- Volunteers
- 490 people
- Sponsor
- Peking University People's Hospital
Heart Failure With Preserved Ejection Fraction
Application of Multimodal Large Language Model in HFpEF
This study will validate the effectiveness of a multimodal large language model to screen for heart failure with preserved ejection fraction (HFpEF), comparing it with the traditional clinical standardized assessment process.
- Trial name
- MeG-HFpEF (NCT06486649)
- Testing
- Multimodal Large Language Model Diagnosis, Routine diagnostic and therapeutic procedure
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Diabetic Foot Ulcer Treatment
Multi-center Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot Ulcer
Yunnan Baiyao has been treating all kinds of wounds for 120 years, but the evidence of Evidence-based medicine that is truly convincing is insufficient, making its best application method unclear.
- Trial name
- NCT06197412
- Testing
- Yunnan Baiyao
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Low Anterior Resection Syndrome, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation in the Treatment of Major LARS
Randomized trial to assess FMT efficacy in improving bowel function for major LARS patients. 40 subjects, blinded, randomized to FMT or probiotics.
- Trial name
- FMT-LARS (NCT06475430)
- Testing
- fecal microbiota transplantation, Formulated probiotic supplements
- Volunteers
- 40 people
- Sponsor
- Peking University People's Hospital
Renal Cell Carcinoma
A Study of AK112 Monotherapy in Advanced/Metastatic Renal Cell Carcinoma
This is an open-label, single arm , Ib/II phase trial to evaluate the efficacy and safety of AK112（ivonescimab）monotherapy as first-line treatment for favourable risk advanced/metastatic renal cell carcinoma (a/m RCC).
- Trial name
- NCT06472895
- Testing
- AK112 monotherapy
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Diabetic Foot, Therapeutics
Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot
Yunnan Baiyao has been treating all kinds of wounds for 120 years, but the evidence of Evidence-based medicine that is truly convincing is insufficient, making its best application method unclear.
- Trial name
- NCT06062576
- Testing
- Yunnan Baiyao
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Urothelial Carcinoma of the Renal Pelvis and Ureter
Neoadjuvant Radiotherapy for High-risk UTUC
The investigators propose to conduct an open-label, single-arm, prospective cohort study to collect and observe high-risk UTUC patients (with clear pathology of urothelial carcinoma and at least one of the following (muscle…
- Trial name
- LUXUS07 (NCT06472752)
- Testing
- Neoadjuvant radiotherapy, Neoadjuvant drug therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University First Hospital
Human Papilloma Virus Infection
Effects of Chinese Medicine and Lactobacillus in Persistent HPV Infection
High risk human papillomavirus (hr-HPV) persistent infection is a high risk factor for cervical cancer. 85% to 90% of hr-HPV infections have the ability to clear on their own, while 10% to 15% of HPV persists further will lead to…
- Trial name
- ELIMVLHPV (NCT06467942)
- Testing
- Chinese medicine and Lactobacillus, Chinese medicine, Lactobacillus
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University People's Hospital
Accuracy of Coplanar Template Assisted Seed Implantation for Abdominal and Pelvic Cancer
Accuracy of Coplanar Template Assisted Seed Implantation for Abdominal and Pelvic Cancer
In recent years, template guidance has been applied and developed in the field of puncture related operations, such as template-assisted radioactive seed implantation.
- Trial name
- NCT05483452
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Peking University Third Hospital
Pudendal Neuralgia, Pulsed Radiofrequency
Combined PRF of the Pudendal Nerve With Ganglion Impar Block Effectively Alleviates Pudendal Neuralgia
Patients with pudendal neuralgia suffer from long-term pain, which severely affects their quality of life. Due to unclear etiology, there is a lack of specific treatment methods.
- Trial name
- PRF (NCT06461312)
- Testing
- Combined pulsed radiofrequency of the pudendal nerve with ganglion impar block
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University People's Hospital
Microbial Colonization, Infected Wound
Compare Wound Sampling Methods Efficacy in Microbiology Culture
Slough was a visible indicator of biofilm, which was the most available specimen from acute and chronic wounds. However, studies believed that slough were poorly accurate, and that the Levine swab was more recommended for…
- Conditions
- Microbial Colonization, Infected Wound, Slough
- Trial name
- NCT06460025
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Peking University Third Hospital
Lung Cancer
Observation on the Frailty Status of Lung Cancer Patients
Using the Integrated Conceptual Model of Frailty (ICMF) and Frailty Framework among Vulnerable Population (FFVP) as theoretical basis, the frailty status of lung cancer patients is described, and the physiological, psychological…
- Trial name
- NCT06448455
- Testing
- Observation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting
Although randomized trials have demonstrated there is no benefit of renal-artery stenting in addition to medical therapy for patients with atherosclerosis renal artery stenosis, many patients indeed gained benefit in daily…
- Trial name
- FAIR-Pilot (NCT05732077)
- Testing
- Dopamine, Fractional Flow Reserve, Renal, Renal artery stenting
- Where
- 13 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Rectal Cancer
Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer
The goal of this clinical trial is to learn if neoadjuvant Fruquintinib and Tislelizumab combined with mCapeOX works to treat mid-high pMMR/MSS locally advanced rectal cancer patients compared with CapeOX.
- Trial name
- PKUCH-R09 (NCT06443671)
- Testing
- CapeOX, Fruquintinib and Tislelizumab combined with mCapeOX
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Peking University Cancer Hospital & Institute
Post Surgical Pain
Patient-reported Outcomes of Postsurgical Pain and Health Related Quality of Life
This study will investigate the impact of post-surgical pain (PSP) on health related quality of life (HRQoL) within the first six months following surgery using patient-reported outcome (PRO) measures, and to investigate medical…
- Trial name
- HRQoL (NCT03926858)
- Where
- 23 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Peking University People's Hospital
Colorectal Cancer, Solid Tumor
Real-world Study to Evaluate the Efficacy and Safety of Liposome Irinotecan
This study is a prospective, multicenter, real-world study. There are four cohorts. Cohorts 1-3 include second-line, posterior-line, and neoadjuvant colorectal cancer patients, respectively.
- Trial name
- NCT06443307
- Testing
- Irinotecan Liposome
- Where
- China
- Volunteers
- 933 people
- Sponsor
- Peking University
Cancer
The Preventive Effect of Chemotherapy-induced Hand-foot Syndrome
this study will use traditional Chinese medicine bath with no obvious side effects combined with case tracking management mode to form nursing measures to prevent hand foot syndrome.
- Trial name
- NCT06441513
- Testing
- Chinese traditional medicine nursing combined with case tracking management, Health Education
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University Third Hospital
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