Clinical trials: sponsored by Peking University
Lung Contusion
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion, particularly the impact on pulmonary ventilation blood flow…
- Trial name
- NCT06386120
- Testing
- PEEP setting strategy
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Gastric Cancer
Financial Incentives and Motivational Intervention to Improve Gastric Cancer Screening in China
Gastric cancer, also known as stomach cancer, is a serious disease that affects the stomach. It's one of the most common types of cancer, and sadly, many people die from it each year.
- Trial name
- NCT06384300
- Testing
- Financial Incentives, Motivational Intervention, Mixed Intervention
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Placenta Accreta Spectrum
Risk Factors, Prognosis and Prediction Models for Placenta Accreta Without Prior Cesarean Section
1. Identify the risk factors for Placenta accreta spectrum (PAS) disorders in women without prior caesarean section (CS). 2. Clarify the prognostic factors of the disease and explore individualized treatment options to improve…
- Trial name
- NCT06383923
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Autism Spectrum Disorders
Effectiveness and Mechanism of Online Peer Companion Intervention on Children With Autism Spectrum Disorders
The goal of this interventional study was to examine the effectiveness and mechanism of online peer companion intervention (OPCI) on the social abilities and mental health of ASD children.
- Trial name
- NCT06147141
- Testing
- Online Peer Companion Intervention, Wait-List
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Mental Health Wellness, Cognitive Function
Children to Adults Mental and Psychosomatic Health Study (CAMPS)
This study titled the Children to Adults Mental and Psychosomatic Health Study (CAMPS), aims to explore the interplay between mental health, psychosomatic factors, and adverse childhood experiences (ACE) across a broad age range…
- Conditions
- Mental Health Wellness, Cognitive Function, Physical Symptoms
- Trial name
- NCT05621278
- Where
- China
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Deep Learning, Ultrasound
Deep-learning For Ultrasound Classification of Anterior Talofibular Ligament Injury
Ultrasound (US) is a more cost-effective, accessible, and available imaging technique to assess anterior talofibular ligament (ATFL) injuries compared with magnetic resonance imaging (MRI).
- Conditions
- Deep Learning, Ultrasound, Anterior Talofibular Ligament
- Trial name
- NCT06372873
- Testing
- re-evaluate by two senior radiologists in our medical center
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Peking University People's Hospital
Maternal Hypertension
The Effect of CPAP on Maternal and Infant Outcomes in Pregnant Women With OSAS
The goal of this clinical trial is to learn about the impact of CPAP on the maternal and infant outcomes of women with obstructive sleep apnea syndrome.
- Trial name
- NCT06344702
- Testing
- CPAP
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Unresectable Hepatocellular Carcinoma
Anti-PD-1/PD-L1 Combined With Anti-angiogenic Agents as First-line Treatment for Unresectable HCC
This is a multicenter, randomized, open-label clinical study to evaluate the efficacy and safety of Adebrelimab plus Apatinib (cohort 1), or Adebrelimab plus Bevacizumab (cohort 2), or Camrelizumab plus Apatinib (cohort 3) as…
- Trial name
- NCT06360042
- Testing
- Adebrelimab plus Apatinib, Adebrelimab plus Bevacizumab, Camrelizumab plus Apatinib
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Peking University Cancer Hospital & Institute
Ultrasound, Anterior Talofibular Ligament
Deep-learning Enabled Ultrasound Diagnosis of Anterior Talofibular Ligament Injury
Ultrasound (US) is a more cost-effective, accessible, and available imaging technique to assess anterior talofibular ligament (ATFL) injuries compared with magnetic resonance imaging (MRI).
- Conditions
- Ultrasound, Anterior Talofibular Ligament, Deep Learning
- Trial name
- NCT06373029
- Testing
- Ultrasound examination
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University People's Hospital
Relapsed/Refractory Multiple Myeloma
A Real World Study of Equecabtagene Autoleucel in Subjects With Relapsed and Refractory Multiple Myeloma.
This study is a multicenter, observational, single-arm real world study. The purpose of this study is to describe demographic and disease characteristics, treatment patterns, and clinical outcomes in the real-world setting among…
- Trial name
- NCT06369935
- Testing
- Equecabtagene Autoleucel
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Peking University People's Hospital
Kidney Cancer
Optimization of Management for Sporadic Bilateral Renal Cell Carcinoma
Sporadic bilateral renal cell carcinoma (BRCC) is a rare situation of RCC. The treatment for BRCC is controversial and there is a lack of authoritative guidelines about the management of BRCC.
- Trial name
- NCT06369519
- Testing
- Surgery treatment or local tumor destruction.
- Where
- China
- Volunteers
- 3,677 people
- Sponsor
- Peking University First Hospital
Intrahepatic Cholestasis of Pregnancy
Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy
This study hopes identify the main pruritogens of ICP pruritus and provide new insights for the diagnosis, prediction, and treatment of ICP.
- Trial name
- NCT06366659
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University
Cholestasis, Intrahepatic Cholestasis of Pregnancy
Investigation of the Pruritogens of Liver-related Diseases
This study hopes investigate the itch-inducing ability of different potential pruritogen candidates of cholestasis pruritus, especially the intrahepatic cholestasis of pregnancy (ICP).
- Trial name
- NCT06364969
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Respiratory Distress Syndrome of Newborn
A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+)
This study plans to conduct a DEX dose halving study and a normal dose study in 34+0-35+6 GW women with preterm preterm labour. In addition, this study plans to conduct a DEX dose halving study and a normal dose study in 34-38+6…
- Trial name
- NCT06350565
- Testing
- Dexamethasone
- Volunteers
- 48 people
- Sponsor
- Peking University Third Hospital
Dorsal Scapular Nerve Entrapment
Dorsal Scapular Nerve Injection Combined With Muscle Needle Release
Ultrasound-guided perineural injection (PIT) of 5% dextrose (D5W) hydrodissection has been widely used in the treatment of peripheral entrapment neuropathies.
- Trial name
- NCT06329960
- Testing
- Ultrasound-guided injection combined with needle release
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Adenomyosis
Adenomyosis Patients With Infertility and Immunological Factors
Infertile patients with adenomyosis who met the inclusion and exclusion criteria, after signing the informed consent form, the researchers recorded the clinical information of the patients and initiated the in vitro…
- Trial name
- NCT06123975
- Testing
- Venous blood collection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Health
Effect of Oral D-mannose Tablets on Pharmacokinetics of Dabigatranate in Healthy Adults
The aim of this study is to investigate the effects of oral D-mannose tablets for 2 consecutive weeks on the pharmacokinetics of dabigatrun etexilate, a P-glycoprotein probe substrate drug, in healthy adults
- Trial name
- NCT06360055
- Testing
- Dabigatran Etexilate, D-mannose
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Thyroid Eye Disease
Exploring the Value of 18F-AlF-FAPI PET/CT in Assessing the Activity of Thyroid Eye Disease
FAPI PET has been developed as a promising approach for the evaluation of fibroinflammatory, such as in inflammatory bowel disease.
- Trial name
- NCT06359795
- Testing
- 18F-AlF-FAPI PET/CT, 99mTc-DTPA SPECT/CT
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility, Male, Azoospermia, Nonobstructive
Machine Learning Based-Personalized Prediction of Sperm Retrieval Success Rate
Non-obstructive azoospermia (NOA) stands as the most severe form of male infertility. However, due to the diverse nature of testis focal spermatogenesis in NOA patients, accurately assessing the sperm retrieval rate (SRR) becomes…
- Trial name
- NCT06358794
- Testing
- Machine learning-based predictive model
- Where
- China
- Volunteers
- 2,612 people
- Sponsor
- Peking University Third Hospital
HER2 Positive Solid Tumor
KN026 Combined With KN046 in Subjects With HER2 Positive Solid Tumor
This is a phase Ib, open-label, dose-escalation and expansion study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of KN026 combined with KN046 in subjects with advanced HER2 positive solid tumors.
- Trial name
- NCT04040699
- Testing
- KN026 combined with KN046
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Peking University
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