Clinical trials: sponsored by Peking University First Hospital
Acute Mountain Sickness
EleVation carE: a Randomized Controlled Trial on the Prevention of Acute Mountain Sickness With Suxiao Jiuxin Pill
The aim of this randomized, controlled trial is to evaluate the safety and efficacy of Suxiao Jiuxin Pills for prevention of acute mountain sickness (AMS) after high altitude exposure in healthy volunteers, and its influences on…
- Trial name
- EVEREST (NCT06531161)
- Testing
- Suxiao Jiuxin Pill
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Prostate Cancer
The Role of Levator Ani Muscle Reconstruction Technology in Urinary Incontinence Recovery
This study is a single center, single blind, prospective randomized controlled trial. Patients undergoing robot assisted laparoscopic radical prostatectomy for prostate cancer were randomly divided into 1:1:1 groups, using…
- Trial name
- NCT06543420
- Testing
- lateral reconstruction, posterior reconstruction
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Peking University First Hospital
Prostate Cancer
Study of [177Lu]Lu-PSMA-137 In Metastatic Castrate Resistant Prostate Cancer（mCRPC）
This study is a prospective, single-center, single-arm clinical trial consisting of two parts. In Part A, 3 participants were enrolled to receive sequential administrations of low doses of [177Lu]Lu-PSMA-137 and…
- Trial name
- NCT06546527
- Testing
- [177Lu]Lu-PSMA-137
- Volunteers
- 12 people
- Sponsor
- Peking University First Hospital
Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency
Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce…
- Trial name
- VD-PD (NCT05860270)
- Testing
- Cholecalciferol
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Peking University First Hospital
Kidney Cancer
Risk-based Screen and Prognostic Analysis for Second Primary Malignancies in Kidney Cancer Patients
Second primary malignancy (SPM) significantly impacts the survival and prognosis of patients. This study endeavors to identify risk and prognostic factors associated with SPM after first primary kidney cancer and construct…
- Trial name
- NCT06531629
- Testing
- Surgery, radiation therapy and chemotherapy
- Where
- China
- Volunteers
- 72,408 people
- Sponsor
- Peking University First Hospital
Percutaneous Coronary Intervention, Hemostasis
Effect of Patent Hemostatic Device (PHD) With Quantitative Pressure on Radial Artery Hemostasis After CAG/PCI
The objective of this clinical trial is to compare the hemostatic effect of 2 hemostatic devices with or without quantitative pressure on radial arteries after coronary angiography (CAG) or percutaneous coronary intervention…
- Trial name
- PCI (NCT05790603)
- Testing
- Intervention group with PHD-Band, Control group with TR-Band
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Chronic Atrophic Gastritis
Objective Study on Tongue Diagnosis of Chronic Atrophic Gastritis
Chronic atrophic gastritis with intestinal metaplasia or dysplasia is called precancerous lesions of gastric cancer ( PLGC ). It is an important stage in the transformation of normal mucosa to gastric cancer and is significantly…
- Trial name
- NCT06489132
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Acute Myocardial Infarction, Coronary Artery Disease
Survival and cArdiovascular eVents in Patients With Acute Myocardial Infarction
This prospective and prospective cohort study aims to establish a long-term follow-up cohort of patients with acute myocardial infarction, and combine multi-omics studies, wearable devices, artificial intelligence technology…
- Trial name
- SAVING (NCT06489080)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Peking University First Hospital
Urothelial Carcinoma of the Renal Pelvis and Ureter
Neoadjuvant Radiotherapy for High-risk UTUC
The investigators propose to conduct an open-label, single-arm, prospective cohort study to collect and observe high-risk UTUC patients (with clear pathology of urothelial carcinoma and at least one of the following (muscle…
- Trial name
- LUXUS07 (NCT06472752)
- Testing
- Neoadjuvant radiotherapy, Neoadjuvant drug therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University First Hospital
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting
Although randomized trials have demonstrated there is no benefit of renal-artery stenting in addition to medical therapy for patients with atherosclerosis renal artery stenosis, many patients indeed gained benefit in daily…
- Trial name
- FAIR-Pilot (NCT05732077)
- Testing
- Dopamine, Fractional Flow Reserve, Renal, Renal artery stenting
- Where
- 13 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Pregnancy, Obstructive Sleep Apnea
The Effect of OSA on Pregnancy and Fetal Outcomes
This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) on pregnancy and fetal outcomes.
- Trial name
- NCT06391138
- Testing
- Continuous Positive Airway Pressure
- Volunteers
- 500 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea, Chronic Kidney Diseases
The Effect of OSA on Severity and Prognosis of Patients With CKD
This study aims to investigate the influence of obstructive sleep apnea hypopnea syndrome (OSA) on the severity and prognosis of patients with chronic kidney disease (CKD), and to evaluate the therapeutic effect of continuous…
- Trial name
- NCT06393023
- Testing
- Continuous Positive Airway Pressure
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea, IgA Nephropathy
The Effect of OSA on Severity and Prognosis of Patients With IgAN
This study aims to investigate the influence of obstructive sleep apnea hypopnea syndrome (OSA) on the severity and prognosis of patients with IgA nephropathy (IgAN), and to evaluate the therapeutic effect of continuous positive…
- Trial name
- NCT06393036
- Testing
- Continuous Positive Airway Pressure
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea, Chronic Tonsillitis
Effect of OSA Resulting From Chronic Tonsillitis on Pregnancy Outcomes
This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) resulting from chronic tonsillitis on pregnancy outcomes.
- Conditions
- Obstructive Sleep Apnea, Chronic Tonsillitis, Pregnancy
- Trial name
- NCT06391151
- Testing
- exposure: OSA resulting from chronic tonsillitis
- Volunteers
- 500 people
- Sponsor
- Peking University First Hospital
Cutaneous T-Cell Lymphoma/Mycosis Fungoides, Cutaneous T Cell Lymphoma
A Study of Molecular Subtyping-based Therapeutic Strategies for Cutaneous T-cell Lymphoma
Cutaneous T-cell lymphoma (CTCL) is a group of diseases resulting from clonal hyperplasia of memory T cells in the skin. The increasing incidence and high treatment costs have posed significant challenges to public health and the…
- Trial name
- AMITY (NCT06436677)
- Testing
- molecular subtype based treatment
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Type 2 Diabetes
Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients
This study evaluated the efficacy and safety of initial combined treatment of Henggliptin, Retagliptin and Metformin by including new type 2 diabetes patients.
- Trial name
- NCT06417489
- Testing
- Combination therapy, Sequential treatment group
- Volunteers
- 160 people
- Sponsor
- Peking University First Hospital
VHL Syndrome, Renal Cell Carcinoma
Establishment of a Multidimensional Prediction Model for the Natural Course of VHL Disease-related Renal Cell Carcinoma
VHL syndrome is a rare hereditary tumor syndrome caused by mutation of tumor suppressor gene VHL. One of the most important clinical manifestations and main cause of death is VHL-related renal cell carcinoma (RCC).
- Trial name
- NCT06391879
- Testing
- Single cell sequencing, whole genome and metabolomic sequencing
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Prostate Adenocarcinoma
Exploration of the Value of PSMA PET/CT in Dynamic Monitoring of the Efficacy of Novel Endocrine Therapy in Patients With Metastatic Hormone Sensitive Prostate Cancer
1. Based on the treatment response and prognosis of mHSPC patients with novel endocrine therapy, a PSMA PET whole-body tumor burden classification was constructed to guide treatment and evaluate prognosis. 2.
- Trial name
- NCT06387238
- Testing
- PSMA PET/CT
- Volunteers
- 150 people
- Sponsor
- Peking University First Hospital
Kidney Cancer
Optimization of Management for Sporadic Bilateral Renal Cell Carcinoma
Sporadic bilateral renal cell carcinoma (BRCC) is a rare situation of RCC. The treatment for BRCC is controversial and there is a lack of authoritative guidelines about the management of BRCC.
- Trial name
- NCT06369519
- Testing
- Surgery treatment or local tumor destruction.
- Where
- China
- Volunteers
- 3,677 people
- Sponsor
- Peking University First Hospital
COPD
A Multicenter, Prospective Cohort Study of Preserved Ratio Impaired Spirometry(PRISm) in a Population
Chronic obstructive pulmonary disease (COPD) is the most common chronic tract disease and the third leading cause of death worldwide.
- Trial name
- NCT06340295
- Where
- 6 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Peking University First Hospital