Clinical trials: sponsored by Peking University First Hospital
ST-Elevation Myocardial Infarction
China STEMI Care Project
The China ST-elevation myocardial infarction (STEMI) Care Project (CSCAP) aims to improve the reperfusion treatment rate and shorten the total duration of myocardial ischemia by establishing a regional STEMI treatment network…
- Trial name
- NCT03821012
- Testing
- in-hospital process optimization, PPCI hospital-based regional STEMI transfer network construction, the whole-city STEMI care network construction
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Peking University First Hospital
Neuropathy of Diabetes
Phase I Single-dose Escalation Clinical Trial of Salvianolic Acid A Tablets
Salvianolic acid A has a variety of pharmacological effects, such as: anti-oxidation, scavenging oxygen free radicals, anti-fibrosis, anti-myocardial ischemia, anti-coagulation, anti-thrombosis, anti-tumor, etc.
- Trial name
- NCT03791125
- Testing
- Salvianolic Acid A
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Healthy
Effect of Food on Pharmacokinetics of Salvianolic Acid A in Healthy Subjects
This study is an open-label, randomized, cross-over design with two single-dose treatment periods and a washout of at least 3~5 days in between each treatment visit.
- Trial name
- NCT03791463
- Testing
- salvianolic acid A
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Proton Therapy, Immunotherapy
Combination of Proton Therapy With Immunotherapy in Multiple Metastases Cancer
The purpose of this research study is to compare the effects (good and bad) on subjects and their cancer using proton radiation therapy in combination with immunotherapy(ie.
- Conditions
- Proton Therapy, Immunotherapy, Neoplasm Metastasis
- Trial name
- PI-MMC (NCT03765190)
- Testing
- Radiation: Proton Therapy+PD-1 Ab
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Proton Therapy, Immunotherapy
Combination of Hypofractionated Proton Therapy With Immunotherapy
The purpose of this research study is to compare the effects (good and bad) on subjects and their cancer using hypofractionated proton radiation therapy in combination with immunotherapy(ie.
- Trial name
- I-HypoPT (NCT03764787)
- Testing
- Radiation+PD-1 Ab
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Hepatitis B, Liver Fibrosis
A Study in Reversing Hepatic Fibrosis or Cirrhosis Related to Hepatitis B Virus and Finding Biomarkers
The aim of our study is to validate the non-invasive model which was constructed by our previous study for evaluating liver fibrosis or cirrhosis caused by hepatitis B virus in mainland China and to find a therapeutic regimen to…
- Trial name
- NCT03568578
- Testing
- Entecavir 0.5 mg, Anluohuaxian Pill 12g
- Where
- 18 sites in China
- Volunteers
- 450 people
- Sponsor
- Peking University First Hospital
Adult Patients, Total Knee Arthroplasty
Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty
Single femoral nerve blockade combined with patient-controlled intravenous analgesia are used for postoperative analgesia for patients after TKA in the hospital of the investigators.
- Conditions
- Adult Patients, Total Knee Arthroplasty, Epidural Analgesia, Femoral Nerve Block
- Trial name
- NCT03203967
- Testing
- Epidural morphine, Single femoral nerve block, Intravenous morphine analgesia
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University First Hospital
Neoplasms
Tumor Response in Hypofractionated Radiotherapy
This study will follow-up different immune cell populations in the blood before, during and after high dose radiation therapy which should give new information of the efficacy of Local Hypofractionated Radiotherapy and a…
- Trial name
- TRHR (NCT02854449)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Delirium, C.Surgical Procedure; Cardiac
Dexmedetomidine and Delirium in Patients After Cardiac Surgery
Postoperative delirium (POD) is a frequently occurring complication after cardiac surgery. Its occurrence is associated with worse outcomes of patients, including increased morbidity, prolonged hospital stay, increased medical…
- Conditions
- Delirium, C.Surgical Procedure; Cardiac, Postoperative Complications
- Trial name
- NCT02267538
- Testing
- dexmedetomidine hydrochloride for injection, 0.9% sodium chloride for injection
- Where
- China
- Volunteers
- 285 people
- Sponsor
- Peking University First Hospital
IgA Patients, Hydroxychloroquine
A Study of Hydroxychloroquine Sulfate for Reduction of Proteinuria in Patients With IgA Nephropathy
The investigators study will recruit IgA nephropathy patients with proteinuria range from 0.75 to 3.5g/d even after three-month treatment by sufficient ACEi/ARB.
- Trial name
- NCT02942381
- Testing
- Hydroxychloroquine Sulfate
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Lipid Metabolism Disorders, Postoperative Complications
Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event
Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular…
- Trial name
- NCT03344224
- Testing
- laboratory test
- Volunteers
- 50,000 people
- Sponsor
- Peking University First Hospital
Acute Kidney Injury
Circulatory Management and Acute Kidney Injury in Patients Undergoing Partial Nephrectomy
The purpose of this study is to investigate whether circulatory management based on LiDCOrapid hemodynamic monitoring can reduce the incidence of acute kidney injury in patients undergoing partial nephrectomy when compared with…
- Trial name
- NCT02803372
- Testing
- Goal-directed circulatory management, Routine circulatory management
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University First Hospital
Osteoporosis
Percutaneous Vertebroplasty Versus Conservative Treatment in GIOPVCF
Based on the case reports and other literature, the investigators hypothesize that using PVP for treating GIOPVCF is associated with increased risk of vertebral refractures and does not provide further benefits compared to…
- Trial name
- NCT03330340
- Testing
- Percutaneous Vertebroplasty
- Volunteers
- 106 people
- Sponsor
- Peking University First Hospital
Upper Tract Urothelial Carcinoma, Bladder Recurrence
Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Diagnostic Ureteroscopy for Primary Upper Tract Urothelial Carcinoma Patients
This clinical trial is designed to evaluate the efficacy of single immediate intravesical chemotherapy instillation in the prevention of bladder recurrence after diagnostic ureteroscopy for upper tract urothelial carcinoma (UTUC)…
- Trial name
- NCT02740426
- Testing
- Pirarubicin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Recurrence, Metastasis
Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma)
This clinical trial is designed to evaluate the role of lymph node dissection in the prevention of recurrence and metastasis after radical nephroureterectomy for high-risk primary upper tract urothelial carcinoma (UTUC) patients.
- Conditions
- Recurrence, Metastasis, Upper Tract Urothelial Carcinoma, Lymph Node Dissection
- Trial name
- UTUC (NCT03230201)
- Testing
- Lymph node dissection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Chronic Obstructive Pulmonary Disease
Exhaled Breathing Condensate (EBC) Features and Lung Function Decline in Chinese Adults
Chronic obstructive lung disease (COPD) is a worldwide leading and still increasing cause of chronic morbidity and mortality. The important issue of COPD is its delayed diagnosis.
- Trial name
- NCT02037828
- Where
- China
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Labor Pain, Analgesia, Obstetrical
Individualized Timing of Analgesia and Effectiveness of Labor Analgesia
Neuraxial analgesia is the gold standard to relieve labor pain. A recent "Practice guidelines for obstetric anesthesia" suggests that neuraxial analgesia should be provided in the early stage of labor (cervical dilation < 5 cm)…
- Conditions
- Labor Pain, Analgesia, Obstetrical, Early Medical Intervention
- Trial name
- NCT02920489
- Testing
- Individualized epidural analgesia, Routine epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Coronary Heart Disease
Efficacy of Dun Ye Guan Xin Ning Tablet in Patients With Stable Angina Pectoris
This registry is designed to investigate factors affecting the efficacy of Dun Ye Guan Xin Ning tablet on patients with stable angina.
- Trial name
- NCT03198091
- Testing
- Dun Ye Guan Xin Ning
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University First Hospital
Aged, Surgical Procedures, Operative
Dexmedetomidine and Long-term Outcome in Elderly Patients After Surgery
Delirium is a frequent postoperative complication. Its occurrence is associated with worse long-term outcomes. In a previous randomized controlled trial, prophylactic low-dose dexmedetomidine infusion during the early…
- Conditions
- Aged, Surgical Procedures, Operative, Delirium, Dexmedetomidine
- Trial name
- NCT02809937
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Peking University First Hospital
Gestational Diabetes, Diabetes
The DNA Methylation of ARHGEF11 in Macrosomia
Background Macrosomia at birth is associated with subsequent susceptibility to obesity, abnormal glucose metabolism, hypertension and dyslipidaemia.
- Conditions
- Gestational Diabetes, Diabetes, Macrosomia, Fetal
- Trial name
- NCT03165643
- Testing
- OGTT
- Volunteers
- 239 people
- Sponsor
- Peking University First Hospital