Clinical trials: sponsored by Penn State University
Liver Transplantation
Correlation Between Release of Cytokines From Liver Graft and Hemodynamic Instability
The primary goal of this project is to identify the source of cytokines that are released into circulation during graft reperfusion. Seventeen patients scheduled to have adult cadaveric liver transplantation at the Milton S.
- Trial name
- NCT01120743
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Penn State University
Physical Activity
Physical Activity and Daily Experiences Study
Lack of physical activity is associated with negative health outcomes, including obesity, diabetes, and cardiovascular disease. There are calls from NIH and medical organizations to integrate the use mobile devices, such as…
- Trial name
- NCT02005042
- Testing
- Feedback on smartphone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Penn State University
Umbilical Cord, Infection
Triple Dye Plus Alcohol Versus Triple Dye Alone for Newborn Umbilical Cord Care
In the United States (U.S.) there currently is no standard method of umbilical cord care, resulting in varying practices within and across institutions.
- Trial name
- NCT00127699
- Testing
- Alcohol swab of umbilical cord
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cystic Fibrosis, Abdominal Pain
An Investigation of the Association Between Helicobacter Pylori Infection and Abdominal Pain in Cystic Fibrosis Patients
Cystic fibrosis (CF) is the most common lethal autosomal recessive disease among Caucasians. While the pulmonary disease in CF receives most of the attention, gastrointestinal diseases occur in >95% of CF individuals and can…
- Conditions
- Cystic Fibrosis, Abdominal Pain, Helicobacter Pylori Infection
- Trial name
- NCT00765401
- Where
- United States
- Sponsor
- Penn State University
Irritable Bowel Syndrome
Effect of Acupuncture on Symptoms of Diarrhea and Pain in IBS
Acupuncture has been used for centuries in China in the treatment of diarrhea. Our hypothesis is that acupuncture is effective in the treatment of abdominal pain and diarrhea in patients with diarrhea-predominant IBS
- Trial name
- NCT00219505
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Penn State University
Venous Thromboembolism, Deep Venous Thrombosis
Prevalence and Risk Factors of Venous Thromboembolism in Hospitalized Pediatric Patients
The issue to be studied is the prevalence of venous thromboembolism (VTE) in hospitalized pediatric patients, and to identify if there are subgroups of patients who may be at higher risk.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pediatrics
- Trial name
- pediatric DVT (NCT01140386)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity
Healthy Sleeping and Feeding During Infancy
Childhood obesity has reached epidemic proportions and its prevalence continues to rise, even among very young children. A recent report from the National Health and Nutrition Examination Survey (NHANES) revealed that from 1999…
- Trial name
- NCT00125580
- Testing
- Infant sleep instruction
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pain, Hyperalgesia
Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers
Tis study was designed to test the hypothesis that pretreatment with valdecoxib, prior to injury could reduce or prevent the development of secondary hyperalgesia around the area of primary injury.
- Trial name
- NCT00260325
- Testing
- valdecoxib
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
Hidradenitis Suppurativa
Treatment of Hidradenitis Suppurativa Using Etanercept
Therapy with etanercept, a TNF inhibitor will reverse the inflammation, symptoms and quality of life and allow healing of HS.
- Trial name
- NCT00949546
- Testing
- etanercept
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Penn State University
Respiratory Tract Diseases
Effect of Effect of a Medicated Topical Therapy , Petrolatum, and No Treatment on Nocturnal Cough
This study seeks to subjectively evaluate whether a single application of Vicks® VapoRub® (VVR) ointment or a control ointment (petrolatum) will be superior to no treatment for control of nocturnal cough and congestion due to…
- Trial name
- NCT00743990
- Testing
- Ointment containing camphor, eucalyptus oil, and menthol, Petroleum jelly
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Penn State University
Seizures
Dilantin Levels With Continuous Delivery of Enteral Feedings - A Pilot Study
It is unclear how enteral nutrition via a feeding tube should be given when a patient is receiving enteral Dilantin. Some caregivers hold the feedings for one hour before and one hour after the Dilantin dose to insure adequate…
- Trial name
- NCT00219479
- Testing
- Phenytoin (Dilantin) levels during change in enteral feeding
- Volunteers
- 3 people
- Sponsor
- Penn State University
Cough, Respiratory Tract Infections
Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep
Cough is the most common reason for an acute care doctor's visit in the United States. Cough can affect sleep for both coughing children and their parents.
- Trial name
- NCT00127686
- Testing
- Dextromethorphan, Buckwheat Honey
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Penn State University
Carpal Tunnel Syndrome
Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release
Although some surgeons prefer one technique rather than the other, both endoscopic and open carpal tunnel release procedures are accepted as standard of care surgeries to relieve carpal tunnel syndrome.
- Trial name
- NCT00880295
- Testing
- endoscopic carpal tunnel release, open carpal tunnel release
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Penn State University
Intraoperative Floppy Iris Syndrome
Retrobulbar Injection of Anesthesia Versus Healon 5 in the Management of Intraoperative Floppy Iris Syndrome
In this study, the investigators plan to compare the incidence and complications of intraoperative floppy iris syndrome (IFIS) during cataract surgery in patients taking tamsulosin (Flomax) and treated with retrobulbar injection…
- Trial name
- NCT00627913
- Testing
- Healon 5 injection, Retrobulbar anesthetic injection
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Penn State University
Eating Behavior, Dietary Habits
Early Dieting in Girls: a Longitudinal Cohort Study
This longitudinal observational cohort followed the growth and development of non-Hispanic white girls from age 5 to 15 years, with a focus on the development of the controls of food intake.
- Conditions
- Eating Behavior, Dietary Habits, Weight, Body
- Trial name
- NCT03342430
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Penn State University
Delirium Superimposed on Dementia
Early Nurse Detection and Management of Delirium
Delirium (acute confusion) is common and costly in persons with dementia, resulting in longer hospital stays, more complications, and greater functional decline.
- Trial name
- END-DSD (NCT01505257)
- Testing
- END-DSD
- Where
- 2 sites in United States
- Volunteers
- 391 people
- Sponsor
- Penn State University
Generalized Anxiety Disorder
Desensitization and Cognitive Therapy in General Anxiety.
This study will test the feasibility and safety of adding interpersonal and emotional processing techniques to standard cognitive behavioral therapy for generalized anxiety disorder.
- Trial name
- NCT00951340
- Testing
- Cognitive behavioral therapy (CBT), Emotional processing and interpersonal therapy, Listening therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Penn State University
Nutrient Pharmacokinetics
Vitamin Gum Pharmacokinetics
The present study will investigate the oral release and systemic pharmacokinetics of a panel water- and fat-soluble vitamins from two commercially-produced chewing gum formulations. Vitaball, Inc. (Ft.
- Trial name
- NCT03230396
- Testing
- Vitamingum Sport, Vitamingum Immunity
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Penn State University
Menstrual Irregularity
Increased Calorie Intake to Reverse Energy Deficiency in Exercising Women: Impact on Bone and Menstrual Cyclicity
The purpose of this study is to examine the effects of increased food intake on the menstrual cycle and bone health in physically active women who have irregular or absent menstrual cycles.
- Trial name
- NCT00392873
- Testing
- EAMD+Calories
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Penn State University
Substance Use
Adaptation Processes in School-Based Substance Abuse Programs
The goals of this study are to develop a middle school substance use prevention curriculum for underserved rural youth and evaluate its efficacy compared to the existing, multicultural curriculum.
- Trial name
- NCT01755533
- Testing
- Rural curriculum, Classic curriculum
- Where
- United States
- Volunteers
- 2,827 people, healthy volunteers welcome
- Sponsor
- Penn State University