Clinical trials: sponsored by Poitiers University Hospital
Oncology, Autoimmunity
Rheumatologic Adverse Events and Cancer Immunotherapy
In this study, every patient with cancer who is going to be treated by immunotherapy will fill in a form. In this form, we try to determine if he presents rheumatologic complications of his immunotherapy.
- Conditions
- Oncology, Autoimmunity, Arthritis, Adverse Drug Event
- Trial name
- NCT04791150
- Testing
- Fill in a form
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Poitiers University Hospital
Chorioretinopathy, Obstructive Sleep Apnea
Association Between CRSA and OSA
This goal of this study is to know the association between the central serous chorioretinopathy and the obstructive sleep apnea.
- Trial name
- CRSA (NCT04634786)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Poitiers University Hospital
Chronic Total Occlusion of Coronary Artery, Optical Coherence Tomography
Post-stenting Assessment of Reendothelialization With OFDI After CTO Procedure (PERFECTO)
The objective of PERFECTO is to assess the reendothelialization at 3 months after successfully CTO percutaneous intervention (PCI) with new generation drug eluting stent (DES) by OFDI analysis.
- Conditions
- Chronic Total Occlusion of Coronary Artery, Optical Coherence Tomography, Ischemic Cardiomyopathy, Neointimal Hyperplasia
- Trial name
- PERFECTO (NCT03209843)
- Testing
- Percutaneous recanalization of chronic total occlusion
- Where
- 7 sites in France
- Volunteers
- 122 people
- Sponsor
- Poitiers University Hospital
Obstetric Anal Sphincter Injury
Reproducibility of External Anal Sphincter Elastic Properties Assessment Using Elastography During Pregnancy
The risk prediction of obstetric anal sphincter injury couyl be optimized by considering pregnant women's anal sphincter intrinsic viscoelastic properties.
- Trial name
- SEA ELASTO 1 (NCT04350632)
- Testing
- Shear wave elastography assessment of the external anal sphincter
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Kidney Transplantation
Urinary Tract Infections in Kidney Transplant Recipients
The purpose of this study is to better estimate the prevalence of urinary tract infections (UTI) in kidney transplant (KIT) recipients, and especially multidrug resistant (MDR) bacteria.
- Trial name
- URIKIT (NCT03211026)
- Testing
- No intervention
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Poitiers University Hospital
Pharmacokinetic Study
Toxicokinetic Study of Dichlorobisphenol A After an Oral or Dermal Single Dose in Healthy Volunteer.
The objective of this study is to determine toxicokinetic parameters of deuterated d12-Cl2BPA after the administration of a single low dose (50 µg/kg) to healthy volunteers via oral or dermal routes.
- Trial name
- PRECEPT (NCT04788810)
- Testing
- Administration of d12-Cl2BPA
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Pancreatic Adenocarcinoma
Portal Vein Thrombosis Associated With Unresectable Pancreatic Cancers : a Prospective Multicentric Cohort Study
Little is known concerning the management of portal vein thrombosis (PVT) in digestive cancers other than hepato-cellular carcinoma (HCC).
- Trial name
- THROMPAN (NCT04814251)
- Testing
- Observationnal cohort
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Colorectal Cancer
A Program for Improved Family Screening for Colorectal Cancer
A first- degree family history of colorectal cancer (CRC) or adenoma before age 65 is associated with a high risk of CRC. For these high-risk subjects, the French 2013 recommendations advise colonoscopy screening, but…
- Trial name
- COLOR3 (NCT03620877)
- Testing
- Personalized intervention
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Early Ventilation Acquired Pneumonia in Brain Injured Patients
PROPHY-VAP: Prevention of Early Ventilation Acquired Pneumonia (VAP) in Brain Injured Patients by a Single Dose of Ceftriaxone
Ventilation-associated pneumonia (VAP) is the main site of healthcare-associated infections in the brain injured patients, with an incidence rate of 22% to 58%.
- Trial name
- PROPHY-VAP (NCT02265406)
- Testing
- Anti-Infective Agents
- Where
- 8 sites in France
- Volunteers
- 354 people
- Sponsor
- Poitiers University Hospital
Bariatric Surgery Candidate, Weight Loss
Long Term Effect of Bariatric Surgery on Pelvic Floor Disorders
Bariatric surgery is increasingly practiced, as it is the most efficient treatment for morbid obesity. More than eighty percent of the operated patients are women.
- Trial name
- ICONES (NCT04575987)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 709 people
- Sponsor
- Poitiers University Hospital
Pregnancy, Endocrine System
Effect of an Environmental Health Education Program on Pregnant Women in Order to Reduce Endocrine Disruptor Exposition
Endocrine disruptors are known as a cancer cause. On pregnant women, it can induce major foetal pathology and impact growth. Among those molecules, bisphenol-A (BPA) is a plasticizer that can be found on cans and water.
- Conditions
- Pregnancy, Endocrine System, Prevention Program
- Trial name
- NCT03233984
- Testing
- sensibilisation program "Ma maison, mon environnement santé"
- Where
- France
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Chronic Kidney Disease
Study Evaluating the Benefit of Two Immunosuppressive Strategies on Renal Function
Prospective, multicenter, randomized and open label study evaluating the benefit on renal function at 12 months post-transplantation, with an immunosuppression without calcineurin inhibitor at 3 months and combining mycophenolate…
- Trial name
- NCT02334488
- Testing
- Everolimus, Tacrolimus, Mycophenolate sodium
- Where
- 14 sites in France
- Volunteers
- 329 people
- Sponsor
- Poitiers University Hospital
Recurrent Paralysis of Vocal Cords
Efficacy of Oral Corticosteroid Therapy in Recurrent Paralyzes After Thyroidectomy
Thyroidectomy is a common surgical procedure in France. Recurrent paralysis is one of the main complications. Oral corticosteroid therapy are frequently used at a dosage of 1mg/kg for seven days, in case of recurrent paralysis to…
- Trial name
- NCT03553342
- Testing
- Corticoids
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Poitiers University Hospital
Postnatal Depression
Impact of Giving Birth During the Covid 19 Pandemia on Postnatal Women's Depression
Postnatal depression is an important problematic in French population with approximatively 10 -20% of women who suffer from postnatal depression. This pathology may have strong negative impact on both women and neonate's health.
- Trial name
- DEPRECOVID (NCT04368208)
- Testing
- Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Poitiers University Hospital
Skin Disinfection Before Peripheral Venous Catheter Insertion
Estimation of the Incidence of Colonization of Peripheral Venous Catheters After Skin Disinfection With 0.5% Sodium Hypochlorite, Preceded or Not by an Application of 70% Ethanol
The peripheral venous catheter is the most commonly used medical device in the hospital setting. Infectious complications are infrequent, bacterial or fungal, and local or systemic (catheter-related bacteremia).
- Trial name
- DACLEAN (NCT04391660)
- Testing
- 0.5% sodium hypochlorite solution, 0.5% sodium hypochlorite solution and 70% ethanol
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Poitiers University Hospital
Obstructive Sleep Apnea-hypopnea, Oropharyngeal Cancer
Prevalence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Following Squamous Cell Carcinomas of the Oropharynx Treatment by Combined Chemoradiotherapy
The study's aim is to determinate the prevalence of obstructive sleep apnea hypopnea syndrome after treatment by combined chemoradiotherapy in a locally advanced stages treated population of oropharyngeal cancer.
- Trial name
- COROSAS (NCT04440618)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Obstetric Trauma
Optimizing the Obstetrician's Movement During a Simulated Forceps Operative Vaginal Delivery (PERFORMAC)
Operative vaginal delivery is the main risk factor for pelvic floor trauma occurrence and especially for obstetric anal sphincter injuries.
- Trial name
- PERFORMAC (NCT04670380)
- Testing
- Posture and movement analysis during a simulated forceps vaginal operative delivery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
COVID-19
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19
The SARS-CoV-2 coronavirus pandemic is responsible for more than 180,000 deaths worldwide and 20,000 deaths in France. To date, no treatment or vaccine has been successful.
- Trial name
- KILLER (NCT04371965)
- Testing
- Povidone-Iodine
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Poitiers University Hospital
Insulin Treated Type 2 Diabetes With High Risk of Hypoglycemia
Efficacy of Flash Glucose-Sensing Technology on the Occurrence of Cardiac Arrhythmias Associated With Hypoglycemia
Hypoglycemia, frequently asymptomatic, may lead to cardiac arrythmias and induce an increased risk of cardiovascular morbidity and mortality in patients with type 2 diabetes (T2D).
- Trial name
- NCT03570138
- Testing
- FREESTYLE LIBRE device, a Flash Continuous Glucose Monitoring System, Usual self monitoring Blood Glucose device
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Pancreatic Cancer, Circulating Tumor DNA
CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer
With an incidence of more than 11,600 new cases per year in France and an annual number of deaths close to the incidence rate, adenocarcinoma of the pancreas is a public health problem.
- Conditions
- Pancreatic Cancer, Circulating Tumor DNA, KRAS Mutation-Related Tumors
- Trial name
- NCT04560270
- Testing
- Blood samples
- Volunteers
- 69 people
- Sponsor
- Poitiers University Hospital