Clinical trials: sponsored by Poitiers University Hospital
Psoriasis Vulgaris
Psoriatic Inflammation Markers Predictive of Response to Adalimumab
The objective is to compare the initial skin inflammatory transcriptomic profile of psoriatic patient responder to Adalimumab therapy (defined as the achievement of a Psoriasis Area and Severity Index 75 response at 16 weeks)…
- Trial name
- IMPRA (NCT03389984)
- Testing
- cutaneous
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Poitiers University Hospital
Helicobacter Pylori
Performances of a H. Pylori Stool PCR Test
Performance of a non-invasive test for the detection of Helicobacter pylori and its resistance to clarithromycin in stool by Real-Time PCR Amplidiag H. pylori + ClariR (Mobidiag).
- Trial name
- HEPYSTOOL (NCT03566004)
- Testing
- Stool specimen collection
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Poitiers University Hospital
Colorectal Cancer
The Life and Care of Colorectal Cancer Patients After 65 Years and Their Family
Given a context where patients autonomy respect is important, it is necessary to pay a sustained attention to the patients care and life experiences, as well as the families and relatives of patients with colorectal cancer or…
- Trial name
- MACHROAPIK65 (NCT04458740)
- Testing
- biographical interviews
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Poitiers University Hospital
Arrhythmia Atrial
Fluid Responsiveness Evaluation in Patients With Acute Circulatory Failure and Arrhythmia With Atrial Fibrillation: Indice Delta ITV / Delta RR
Fluid therapy is often used as first line treatment of acute circulatory failure, aiming an increase in cardiac output (by improving preload) and in tissue perfusion.
- Trial name
- NCT03461094
- Testing
- Preload assessment and volume expansion
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Poitiers University Hospital
Allergic Bronchopulmonary Aspergillosis
Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded).
Compare the incidence of severe clinical exacerbations in the treatment of ABPA, between a strategy with a maintenance treatment and a conventional strategy without antifungal maintenance therapy.
- Trial name
- NEBULAMB (NCT02273661)
- Testing
- Liposomal amphotericin B (Ambisome®)
- Where
- France
- Volunteers
- 174 people
- Sponsor
- Poitiers University Hospital
Ventilator Associated Pneumonia
Microbial Etiology of Ventilator-associated Pneumonia in COVID-19 Infected Patients
National multicentric observational retrospective case-control study comparing the relative frequency of the various microorganisms responsible for VAP in patients infected or not by SARS-CoV-2 and their resistance to antibiotics.
- Trial name
- NCT04344509
- Testing
- Bacterial species isolated
- Volunteers
- 10,000 people
- Sponsor
- Poitiers University Hospital
Endobronchial Transbronchial Needle Aspiration Lung Cancer Procore
Interest of Procore Needle® for Diagnosis of Lung Cancer
The ProCore ultrasound biopsy needle, used primarily to obtain intra-abdominal tissue core biopsies, has not been widely used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).
- Trial name
- NCT02931461
- Testing
- Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
- Volunteers
- 49 people
- Sponsor
- Poitiers University Hospital
AMD, Age-related Macular Degeneration
Resveratrol for Exudative Age-Related Macular Degeneration
This is an interventional, prospective, randomized, comparative monocentric study aiming to evaluate the safety and efficacy of Resveratrol to reduce the progression of exudative Age-Related Macular Degeneration.
- Conditions
- AMD, Age-related Macular Degeneration, Choroidal Neovascularisation
- Trial name
- AGED (NCT02625376)
- Testing
- Resvega, Trans-Resveratrol
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Poitiers University Hospital
Obstructive Sleep Apnea, Sudden Hearing Loss
OSA and Sudden Sensorineural Hearing Loss
This study studies the prevalence between obstructive sleep apnea syndrome and sensorineural hearing loss. We recruit patients who have been treated for sudden sensorineural hearing loss in Poitiers' University Hospital between…
- Trial name
- SAS-SB (NCT03747874)
- Testing
- ventilatory polygraphy
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Poitiers University Hospital
Sleep Quality, Extubation Failure
Sleep Quality in Intensive Care Unit Patients at High Risk of Extubation Failure
The aim of the study is to evaluate the impact of sleep quality on extubation failure rate in intensive care unit patients at high risk.
- Trial name
- WEAN SLEEP 2 (NCT02911506)
- Testing
- Polysomnography
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Poitiers University Hospital
Preterm Infants, Parent-Child Relations
Impact of Videoconference Updates in Neonatal Intensive Care Unit on Parental Stress of Preterm Infants (VISIO-NEONAT)
The aim of the study is to test the effect of daily videoconference updates between parents of preterm newborns and health care providers which also offer them the possibility of seeing their child on the parental stress in a…
- Conditions
- Preterm Infants, Parent-Child Relations, Parental Stress, Post Partum Depression
- Trial name
- NCT03438071
- Testing
- Videoconferencing
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Poitiers University Hospital
Coronavirus Disease 2019
1,3,7-Trimethylxanthine as a Treatment of COVID-19: Results of a Controlled Study
This is observational study to assess the prognosis of patients hospitalized with COVID-19 confirmed by RT-PCR and exposed to trimethylxanthine (TMX). Trimethylxanthine is the active molecule present in coffee.
- Trial name
- TMX COVID (NCT04395742)
- Testing
- Data collection
- Volunteers
- 93 people
- Sponsor
- Poitiers University Hospital
The Gold Standard for Current SARS CoV2 Detection is RT-PCR
Multicentric Retrospective Observational Study of Thoracic Scanner Performance in COVID Screening.
All patients included in this search will be on anonymized file: Symptomatic patients consulting for suspicion of COVID 19 with indication to a screening (RT-PCR, Scanner) according to the criteria of the Ministry of Health.
- Trial name
- NCT04339686
- Testing
- Thoracic CT Scan
- Where
- France
- Volunteers
- 56,000 people
- Sponsor
- Poitiers University Hospital
Sleep Deprivation, Healthy Volunteers
Effects of Sleep Privation on Sensorimotor Integration of the Upper Limb During a Manual Endurance Test in Healthy Volunteers-Physiological Study
The investigator showed that a night of sleep deprivation halved the duration of an inspiratory endurance test and that this loss of endurance could be secondary to a lack of activation of the pre-motor cortex.
- Conditions
- Sleep Deprivation, Healthy Volunteers, Skeletal Muscle
- Trial name
- NCT03404427
- Testing
- Normal sleep night, Sleepless night
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Systemic Sclerosis
Analysis of Cytokine Expression Pattern in Systemic Sclerosis
By contrast to other proinflammatory cytokines which are found up-regulated in the skin of patients with psoriasis, atopic dermatitis or systemic sclerosis, IL-34 is the only cytokine that undergoes down-regulation.
- Trial name
- SCLEROKINE (NCT03537105)
- Testing
- Skin biopsies
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Poitiers University Hospital
Scheduled General Anaesthesia With Airway Control
Effects of Drinking at PACU Discharge After General Anaesthesia With Airway Control on Aspiration, Vomiting and Patients Comfort
National guidelines about post-operative fasting after general anesthesia are missing. Current clinical practices are highly variable and no study has ever evaluated on a large scale the real risk of an early drinks recovery in…
- Trial name
- I-DRINC (NCT02193737)
- Testing
- Early oral fluid recovery., Delayed oral fluid recovery.
- Where
- France
- Volunteers
- 1,555 people
- Sponsor
- Poitiers University Hospital
Quality of Life
Study of Impact of Art Therapy Sessions Given to Family Caregivers of Children With Type 1 Diabetes
Diagnostic of diabetes in childhood brought modification of family way of life, particularly in child and caregivers lifes. The education patient programs are in France centered on curative competencies of care.
- Trial name
- EDUCARTPED (NCT02797730)
- Testing
- art-therapy sessions
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Acute Pancreatitis
The Use of Perfusion CT Derived Parameters as Early Acute Pancreatitis Severity Biomarker Compared to Clinico Biological Score
The investigators to establish whether early microvascular permeability parameter evaluated by perfusion-CT could be good biomarkers for severity in acute pancreatitis.
- Trial name
- K-PA (NCT03456557)
- Testing
- Perfusion computed tomography.
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Poitiers University Hospital
Major Abdominal Surgery
Observational Study of the Value of Using Obstructive Sleep Apnea-hypopnea Syndrome (CPAP) Ventilation on the Occurrence of Respiratory and Cardiovascular Complications in Patients at High Risk of Obstructive Apnea Syndrome During Postoperative Sleep Surgery of a Major Abdominal Surgery.
The presence of an obstructive sleep apnea-hypopnea syndrome (OSAHS) is a perfectly identified cardiovascular and metabolic risk factor responsible for excess mortality in patients with severe OSAHS, while life expectancy, when…
- Trial name
- APNOSIS-BIS (NCT04345354)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Poitiers University Hospital
Mesenteric Ischemia, Permeability CT Technics
Dynamic Contrast Enhancement Computed Tomography Based Technic to Assess Gastro Intestinal Wall Perfusion : Feasibility Study
This feasibility study has therefore several aims: 1. construct a dedicated CT perfusion protocol for GIT wall perfusion; 2. used a two-compartment pharmacokinetic model which is more adapted that a unique compartment model; 3.
- Trial name
- PERFE-CT (NCT03367065)
- Testing
- Dynamic contrast enhanced computerised tomography
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Poitiers University Hospital