Clinical trials: sponsored by Poitiers University Hospital
Alternative Method of Apnea Test
Comparison of Two Strategies to Realize Apnea Test for the Diagnostic of Brain in Potentiel Organ Donors.
Clinical diagnostic of brain death requires a non-reactive coma, absence of brain stem reflex, and absence of spontaneous breathing.
- Trial name
- APNEE REA (NCT01911286)
- Testing
- Apnea test - Standard, Apnea test - CPAP
- Where
- 17 sites in France
- Volunteers
- 208 people
- Sponsor
- Poitiers University Hospital
Obstructive Sleep Apnea Syndromes
Interest of Treatment of Obstructive Sleep Apnea Syndrome by Constant CPAP and Auto CPAP
The investigators propose a multicentric controlled randomized trial whose goal is to evaluate the possibility of a prediction of the efficiency of APAP (automatic continuous positive airway pressure) and constant CPAP (constant…
- Trial name
- PREDIVARIUS (NCT02749812)
- Testing
- Constant Continuous Positive Airway Pressure, Automatic continuous Positive Airway Pressure
- Volunteers
- 800 people
- Sponsor
- Poitiers University Hospital
Leiomyoma
A Study on the Efficacy of 10 mg Oral Mifepristone for the Treatment of Symptomatic Uterine Leiomyomas
The first indication of hysterectomies in France are uterine leiomyomas. When they are symptomatic leiomyomas are particularly responsables of an increase of menstruations duration and volume.
- Trial name
- NCT00219778
- Testing
- mifepristone
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Poitiers University Hospital
Diabetic Macular Edema
Intravitreal Injections of Ranibizumab With Deferred Laser Grid Laser Photocoagulation for Treatment of Diabetic Macular Edema With Visual Impairment
In the prospective monocentric open label trial patients with diabetic macular edema will be treated with intravitreal injections of ranibizumab given for 3 months then with laser grid at month 4.
- Trial name
- NCT01823965
- Testing
- ranibizumab
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Poitiers University Hospital
Failed Back Surgery Syndrome
Effectiveness and Cost Management of Multicolumn Spinal Cord Stimulation in Neuropathic Pain Patients With Failed Back Surgery Syndrome
Failed back surgery syndrome (FBSS) constitutes a frequent pathology, generates a severe handicap for patients and represents a considerable expense for healthcare system.
- Trial name
- ESTIMET (NCT01628237)
- Testing
- comparison of spinal cord stimulation
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Poitiers University Hospital
Healthy
Comparison of Ertapenem Distribution in the Muscle of Six Healthy Volunteers and Six Critically Ill Patients by Microdialysis
Ertapenem is an antibiotic that is highly bound to plasma protein (> 95%). The effects of this high protein binding on tissue distribution of antibiotics have been few evaluated yet.
- Trial name
- NCT01061047
- Testing
- Ertapeneme
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Chronic Myeloid Leukemia
Safety and Efficacy of Imatinib in Chronic Myelogenous Patients in Relapse After Stem Cell Transplantation
The aim of this phase II trial is asses the tolerability and the effectiveness of imatinib in patients with chronic myelogenous leukemia in chronic phase who are in relapse after stem cell transplantation.
- Trial name
- NCT00219726
- Testing
- Imatinib mesylate
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Prostate Cancer
Comparison of 20-core Versus 12-core Prostate Biopsy Diagnostic Performance in the Detection of Prostate Cancer
The optimal number of prostate cores extracted during a prostate biopsy performed because of a suspected prostate cancer is still debated. The present consensus is to sample 12 cores.
- Trial name
- NCT00992615
- Testing
- prostate biopsy
- Where
- France
- Sponsor
- Poitiers University Hospital
ICU Patients Requiring a Central Venous Access
Chlorhexidine vs Povidone Iodine in Alcoholic Solutions for Prevention of Central Venous Catheter Infection
The best antiseptic solution for cateheter care remains unknown.High concentration in aquous solution or low concentration in alcoholic solution of chlorhexidine actbetter than povidone iodine in aquous solutions.
- Trial name
- NCT00259350
- Testing
- Skin disinfection
- Where
- France
- Volunteers
- 520 people
- Sponsor
- Poitiers University Hospital
Men Who Must Undergo a Prostate Biopsy Related to Prostate Cancer Suspicion.
Short or Long Schemes of Antibiotic Prophylaxis for Prostate Biopsy
The purpose of this study is to determine whether long antibiotic prophylactic is more effective than a short traitement in infective complications for prostate biopsy
- Trial name
- NCT00294749
- Testing
- Ciprofloxacine
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Poitiers University Hospital
Kidney Transplantation
Maintenance Neoral Monotherapy Compared to Bitherapy in Renal Transplantation
We have previously defined factors that predict the long term success of maintenance CsA monotherapy (CsAm) after kidney transplantation : donor age < 40 years, serum creatinine level at the initiation of CsAm £ 125 µmol/L, no…
- Trial name
- NCT00461825
- Testing
- Cyclosporin A: C0: 75-125ng/ml-dose adapted in the 3 groups, Group A: CsA + Azathioprine(1 to 2 mg/kg/day), Group B: CsA + CellCept(500 mg x 2/day)
- Where
- 5 sites in France
- Volunteers
- 207 people
- Sponsor
- Poitiers University Hospital
Chronic Myeloid Leukemia
Safety and Efficacy of Imatinib in Chronic Myelogenous Patients Older Than 70 Years
The aim of this phase II trial is asses the tolerability and the effectiveness of imatinib in patients with chronic myelogenous leukemia in chronic phase with age more than 70, diagnosis of cml is being performed within 1 year.
- Trial name
- NCT00219752
- Testing
- Imatinib mesylate 400 mg
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Chronic Myeloid Leukemia
Safety and Efficacy of Imatinib in Combination With High Dose Chemotherapy for Acute Phase Chronic Myelogenous Patients
The aim of this phase I/II trial is to determine the dose of daunorubicine to be associated with cytarabine and Imatinib for induction therapy in patients with chronic myelogenous leukemia in myeloid acute phase.
- Trial name
- NCT00219765
- Testing
- Imatinib mesylate 600 mg, Cytarabine, Daunorubicine
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Poitiers University Hospital
Pain
Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.
Bone marrow biopsy is a painful medical procedure often performed with local anesthetic. Therefore a double-blind, randomized, controlled trial was carried out in 330 adult patients who where referred for bone marrow biopsy and…
- Trial name
- NCT00219713
- Testing
- nitrous oxide and oxygen
- Where
- France
- Volunteers
- 280 people
- Sponsor
- Poitiers University Hospital